Zobrazeno 1 - 10
of 63
pro vyhledávání: '"Karen Rowland-Yeo"'
Publikováno v:
CPT: Pharmacometrics & Systems Pharmacology, Vol 13, Iss 11, Pp 1841-1855 (2024)
Abstract In breastfeeding mothers, managing medical conditions presents unique challenges, particularly concerning medication use and breastfeeding practices. The transfer of drugs into breast milk and subsequent exposure to nursing infants raises im
Externí odkaz:
https://doaj.org/article/7a7a850c8fed4fd893be827d3384c2a5
Autor:
Nolan D Wood, Danelle Smith, Sally A Kinrade, Mark T Sullivan, Craig R Rayner, David Wesche, Kashyap Patel, Karen Rowland-Yeo
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 18, Iss 8, p e0012351 (2024)
Moxidectin is approved by the US Food and Drug Administration (US FDA) for the treatment of onchocerciasis (river-blindness) due to Onchocerca volvulus in patients aged 12 years and older. In onchocerciasis-endemic areas, mass drug administration (MD
Externí odkaz:
https://doaj.org/article/9212bc1a647c428a840979071a3a8867
Autor:
Jing Liu, Karen Rowland‐Yeo, Almut Winterstein, Simon Dagenais, Qi Liu, Jeffrey S. Barrett, Rui Zhu, Cyrus Ghobadi, Amita Datta‐Mannan, Joy Hsu, Sujatha Menon, Mariam Ahmed, Pooja Manchandani, Paulien Ravenstijn
Publikováno v:
Clinical and Translational Science, Vol 17, Iss 4, Pp n/a-n/a (2024)
Abstract Real‐world data (RWD) and real‐world evidence (RWE) are now being routinely used in epidemiology, clinical practice, and post‐approval regulatory decisions. Despite the increasing utility of the methodology and new regulatory guideline
Externí odkaz:
https://doaj.org/article/ef7db2fce839459fb90fcc8fc8bede48
Autor:
Nada Abla, Eleanor Howgate, Karen Rowland‐Yeo, Maurice Dickins, Mackenzie C. Bergagnini‐Kolev, Kuan‐Fu Chen, Savannah McFeely, Jennifer J. Bonner, Laura G. A. Santos, Nathalie Gobeau, Howard Burt, Zoe Barter, Hannah M. Jones, David Wesche, Susan A. Charman, Jörg J. Möhrle, Jeremy N. Burrows, Lisa M. Almond
Publikováno v:
CPT: Pharmacometrics & Systems Pharmacology, Vol 12, Iss 9, Pp 1335-1346 (2023)
Abstract As part of a collaboration between Medicines for Malaria Venture (MMV), Certara UK and Monash University, physiologically‐based pharmacokinetic (PBPK) models were developed for 20 antimalarials, using data obtained from standardized in vit
Externí odkaz:
https://doaj.org/article/9ba16da913cf47668851fe83f723f4b5
Autor:
Peter J. Kilford, Kuan‐Fu Chen, Kim Crewe, Iain Gardner, Oliver Hatley, Alice Ban Ke, Sibylle Neuhoff, Mian Zhang, Karen Rowland Yeo
Publikováno v:
CPT: Pharmacometrics & Systems Pharmacology, Vol 11, Iss 7, Pp 822-832 (2022)
Abstract Physiologically‐based pharmacokinetic (PBPK) modeling is being increasingly used in drug development to avoid unnecessary clinical drug–drug interaction (DDI) studies and inform drug labels. Thus, regulatory agencies are recommending, or
Externí odkaz:
https://doaj.org/article/5516ed2a72b542b39b08ffd22bd4d60c
Autor:
Xian Pan, Karen Rowland Yeo
Publikováno v:
CPT: Pharmacometrics & Systems Pharmacology, Vol 11, Iss 5, Pp 535-539 (2022)
Externí odkaz:
https://doaj.org/article/8ce425637c544a9d8358a2086f0ffa88
Publikováno v:
CPT: Pharmacometrics & Systems Pharmacology, Vol 11, Iss 3, Pp 373-383 (2022)
Abstract There has been a significant increase in the use of physiologically based pharmacokinetic (PBPK) models during the past 20 years, especially for pediatrics. The aim of this study was to give a detailed overview of the growth and areas of app
Externí odkaz:
https://doaj.org/article/6883167fb0144d8eb00309beb24c18c2
Publikováno v:
CPT: Pharmacometrics & Systems Pharmacology, Vol 10, Iss 9, Pp 1071-1080 (2021)
Abstract A combination of olanzapine and samidorphan (OLZ/SAM) was recently approved by the US Food and Drug Administration for treatment of patients with schizophrenia or bipolar I disorder. The effects of moderate hepatic impairment on the pharmaco
Externí odkaz:
https://doaj.org/article/85dd3efed4b34c3e9defccc5818900c8
Publikováno v:
CPT: Pharmacometrics & Systems Pharmacology, Vol 10, Iss 9, Pp 967-972 (2021)
Pediatric physiologically‐based pharmacokinetic (PBPK) models have broad application in the drug development process and are being used not only to project doses for clinical trials but increasingly to replace clinical studies. However, the approac
Externí odkaz:
https://doaj.org/article/fcef0e0080e344e9b7c8472297020456
Autor:
Karen Rowland Yeo, Stefanie Hennig, Sriram Krishnaswami, Natasha Strydom, Vivaswath S. Ayyar, Jonathan French, Vikram Sinha, Eric Sobie, Ping Zhao, Lena E. Friberg, France Mentré
Publikováno v:
CPT: Pharmacometrics & Systems Pharmacology, Vol 10, Iss 7, Pp 649-657 (2021)
Externí odkaz:
https://doaj.org/article/0d5d260e746c4c74bf74dee95a357133