Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Karen Roessner"'
Publikováno v:
The Journal of Immunology. 170:2702-2710
γδ T cells accumulate at epithelial barriers and at sites of inflammation in various infectious and autoimmune diseases, yet little is understood about the function of tissue-infiltrating γδ T cells. We observe that γδ T cells of the Vδ1 subse
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0bcb97fbbe8c6efe5c0fe1cce023adb1
https://doi.org/10.4049/jimmunol.170.5.2702
https://doi.org/10.4049/jimmunol.170.5.2702
Autor:
Michael S. Vincent, Karen Roessner, Timothy Sellati, Christopher D. Huston, Leonard H. Sigal, Samuel M. Behar, Justin D. Radolf, Ralph C. Budd
Publikováno v:
The Journal of Immunology. 161:5762-5771
Lyme arthritis synovial fluid contains a large proportion of γδ T cells that proliferates upon stimulation with the causative spirochete, Borrelia burgdorferi. A panel of Borrelia-reactive γδ T cell clones was derived from synovial fluid of two p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d6cab8e3d40a16d2f3b9aab7aa59c0af
https://doi.org/10.4049/jimmunol.161.10.5762
https://doi.org/10.4049/jimmunol.161.10.5762
Autor:
Leonard H. Sigal, Sheldon M. Cooper, Harsh Trivedi, Karen Roessner, Lakshmi K. Gaur, Diantha B. Howard, John M. Aversa, Ralph C. Budd
Publikováno v:
Infection and Immunity. 66:1092-1099
A common concern with many autoimmune diseases of unknown etiology is the extent to which tissue T-lymphocyte infiltrates, versus a nonspecific infiltrate, reflect a response to the causative agent. Lyme arthritis can histologically resemble rheumato
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8dd8fe70b6b1295fe3369cb24eb5be70
https://doi.org/10.1128/iai.66.3.1092-1099.1998
https://doi.org/10.1128/iai.66.3.1092-1099.1998
Autor:
Karen Roessner, Michael S. Vincent, Jürg Tschopp, Ralph C. Budd, David A. Lynch, David L. Wilson, Leonard H. Sigal, Sheldon M. Cooper
Publikováno v:
The Journal of Experimental Medicine
Journal of Experimental Medicine, vol. 184, no. 6, pp. 2109-17
Journal of Experimental Medicine, vol. 184, no. 6, pp. 2109-17
The function of the minor subset of T lymphocytes bearing the gamma delta T cell antigen receptor is uncertain. Although some gamma delta T cells react to microbial products, responsiveness has only rarely been demonstrated toward a bacterial antigen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a3cbd1792c1586c5185d0a27c593b8f
https://doi.org/10.1084/jem.184.6.2109
https://doi.org/10.1084/jem.184.6.2109
Autor:
Ralph C. Budd, Mikako Naito-Hoopes, Lakshmi K. Gaur, Janice A. Nicklas, Sheldon M. Cooper, Connie Dobbs, Diantha B. Howard, Karen Roessner
Publikováno v:
Annals of the New York Academy of Sciences. 756:186-189
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a32d4f4942519a42cc3cc8d1401ca52
https://doi.org/10.1111/j.1749-6632.1995.tb44506.x
https://doi.org/10.1111/j.1749-6632.1995.tb44506.x
Autor:
Ralph C. Budd, Karen Roessner, Sheldon M. Cooper, Mikako Naito-Hoopes, Lakshmi K. Gaur, Diantha B. Howard
Publikováno v:
Arthritis & Rheumatism. 37:1627-1636
OBJECTIVE To determine if the T cell antigen receptor V beta usage of unstimulated rheumatoid arthritis (RA) synovial fluid (SF) T cells is biased compared with those in peripheral blood (PB). METHODS Freshly isolated, matched synovial fluid and peri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f0687db6badd12a9906490f91bc33374
https://doi.org/10.1002/art.1780371112
https://doi.org/10.1002/art.1780371112
Autor:
Jennifer Q. Russell, Erol Fikrig, Ralph C. Budd, Richard A. Flavell, Sheldon M. Cooper, Karen Roessner
Publikováno v:
European Journal of Immunology. 24:320-324
The proliferative response of peripheral blood T cells to the spirochete, Borrelia burgdorferi, can be as pronounced in unexposed normal individuals as it is in Lyme disease patients. This finding was observed using three geographically distinct isol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::199ededcc7910347307778f504509d10
https://doi.org/10.1002/eji.1830240207
https://doi.org/10.1002/eji.1830240207
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 175(9)
γδ T cells participate in the innate immune response to a variety of infectious microorganisms. They also link to the adaptive immune response through their induction of maturation of dendritic cells (DC) during the early phase of an immune respons
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2811aca6f9fd762164d2a63478d410fa
https://pubmed.ncbi.nlm.nih.gov/16237055
https://pubmed.ncbi.nlm.nih.gov/16237055
Publikováno v:
Arthritis and rheumatism. 34(5)
The synovitis of rheumatoid arthritis (RA) is characterized by infiltrates of CD4+ T lymphocytes. To determine the clonal diversity of these cells, we cloned T cells with interleukin-2 (IL-2), alone or with phytohemagglutinin (PHA), directly from act
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3422fbc8c48f5690df08144dfa8b70eb
https://pubmed.ncbi.nlm.nih.gov/2025307
https://pubmed.ncbi.nlm.nih.gov/2025307
Publikováno v:
Arthritis & Rheumatism. 30:1089-1096
Patients with very active rheumatoid arthritis that was being treated only with nonsteroidal antiinflammatory drugs had increased numbers of peripheral blood OKM1+ lymphocytes. In 3 patients, 90 degrees light scatter analysis revealed a double lympho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05ee271e66b2e3476c1fd24bb7496a69
https://doi.org/10.1002/art.1780301002
https://doi.org/10.1002/art.1780301002