Zobrazeno 1 - 10 of 12 pro vyhledávání: '"Karen Rapp Py-Daniel"'
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Photodynamic Therapy treatment of onychomycosis with Aluminium-Phthalocyanine Chloride nanoemulsions: A proof of concept clinical trial
Autor: Rodrigo Barbosa Nunes, Pedro Alencar Gomes Pereira, Cheng-Shi Jiang, Ana Regina Franchi Trávolo, Jinsong Gu, João Paulo Figueiró Longo, Luciano Ferreira Morgado, Karen Rapp Py-Daniel, Paulo Souza Narcizo, Luis Alexandre Muehlmann, Ricardo Bentes Azevedo
Publikováno v: Journal of Photochemistry and Photobiology B: Biology. 173:266-270
The conventional treatment of onychomycosis, a common fungal infection, consists in the use of local and systemic drugs for 4-6 months. This long protocol is often ineffective due to patient compliance, and usually promotes important collateral effec
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3bb2077e86a42993ca68c46d54cc2761
https://doi.org/10.1016/j.jphotobiol.2017.06.010
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5
Tectona grandis leaf extract, free and associated with nanoemulsions, as a possible photosensitizer of mouse melanoma B16 cell
Autor: Igor A Degterev, Karen Rapp Py-Daniel, Fernando Sergio Escocio Drumond Viana de Faria, Ricardo Bentes Azevedo, Jaqueline Rodriguez da Silva, Anselmo Fortunato Ruiz Rodriguez, Ana Lygia dos Santos Camara, Cydia de Menezes Furtado, Everton de Holanda Oliveira
Publikováno v: Journal of Photochemistry and Photobiology B: Biology. 167:242-248
Over the past six years we have been studying extracts from tropical, specially Amazon, plants, to search for new sensitizers for photodynamic therapy of cancer and infectious diseases. Tectona grandis is a genus of tropical hardwood trees in the min
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c08c20e372daf4745187870f0abf1a5
https://doi.org/10.1016/j.jphotobiol.2017.01.004
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7
Self-nanoemulsifying drug-delivery systems improve oral absorption and antischistosomal activity of epiisopiloturine
Autor: Yvonne Primerano Mascarenhas, Maria Adelaide Guimarães, Ana Carolina Mafud, José Roberto S. A. Leite, Karen Rapp Py-Daniel, João Paulo Figueiró Longo, Ricardo Bentes Azevedo, Luiza Ianny de Lima, Cheng-Shi Jiang, Josué de Moraes, Luis Alexandre Muehlmann
Publikováno v: Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Aim: To develop a self-nanoemulsifying drug-delivery system (SNEDDS) able to improve oral absorption of epiisopiloturine (EPI), and test the antischistosomal activity in a mice model. Results: SNEDDS had a nanoscopic size and was able to enhance EPI
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1784fcecdb2e13cf56b60e639792fddf
https://pubmed.ncbi.nlm.nih.gov/29564947
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8
In vivo evaluation of the efficacy, toxicity and biodistribution of PLGA-DMSA nanoparticles loaded with itraconazole for treatment of paracoccidioidomycosis
Autor: Osmindo Rodrigues Pires Júnior, Maria Sueli Soares Felipe, Carolina Madeira Lucci, Antonio Claudio Tedesco, Elaine P. Cunha-Azevedo, Ricardo Bentes Azevedo, Anamélia Lorenzetti Bocca, Marigilson P. Siqueira-Moura, Karen Rapp Py-Daniel
Publikováno v: Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Itraconazole(ITZ) – an antifungal agent of the azole class – is clinically used to treat a variety of fungal infections. Among them, paracoccidioidomycosis (PCM), a fungal infection caused by Paracoccidioides brasiliensis, is the most prevalent s
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::89ed18874535aa46626021f4b723b53f
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9
UHPLC-MS and MALDI-MS study of aluminum phthalocyanine chloride and development of a bioanalytical method for its quantification in nanoemulsions and biological matrices
Autor: Javier Calvo, Ricardo Bentes Azevedo, Karen Rapp Py-Daniel, Sergio Moya, M C Carlos Infante, Osmindo Rodrigues Pires Júnior
Publikováno v: Talanta. 179
Metal phthalocyanines are promising components in photodynamic therapy. Aluminum phthalocyanine chloride (AlClPc) has been used to treat oral cancer in mice, human carious tissue, lung cancer cells and other conditions. To overcome the high hydrophob
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f0e87051cf4c3fd93e4c9e6b4a80c1e
https://pubmed.ncbi.nlm.nih.gov/29310217
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10
Highly efficient photodynamic therapy colloidal system based on chloroaluminum phthalocyanine/pluronic micelles
Autor: Laise Rodrigues de Andrade, Maria A. G. Soler, Ricardo Bentes Azevedo, Paulo Eduardo Narcizo de Souza, Karen Rapp Py-Daniel, Leonardo G. Paterno, Joy S. Namban
Publikováno v: European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V. 103
Phthalocyanine derivatives comprise the second generation of photosensitizer molecules employed in photodynamic therapy (PDT) and have attracted much attention due to their outstanding photosensitizing performance. Most phthalocyanines are hydrophobi
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f33723e730bf9d26d44df6944c0e706b
https://pubmed.ncbi.nlm.nih.gov/27018329
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