Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Karen R. Thickman"'
Autor:
William Bauer, Wenhua Wang, Clara L. Kielkopf, Scott D. Kennedy, Michael R. Green, Ankit Gupta, Joseph E. Wedekind, Karen R. Thickman, Alexandre Maucuer, Valérie Manceau
Publikováno v:
Structure. 21:197-208
SummaryThe essential splicing factors U2AF65 and SF1 cooperatively bind consensus sequences at the 3′ end of introns. Phosphorylation of SF1 on a highly conserved “SPSP” motif enhances its interaction with U2AF65 and the pre-mRNA. Here, we reve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29c74de470ab0632b22a041c21833d60
https://doi.org/10.1016/j.str.2012.10.020
https://doi.org/10.1016/j.str.2012.10.020
Autor:
Karen R. Thickman, Sanford H. Leuba, Grant D. Schauer, Saleem A. Khan, Matt V. Fagerburg, Syam P. Anand, Piero R. Bianco
Publikováno v:
Nucleic Acids Research
The essential DNA helicase, PcrA, regulates recombination by displacing the recombinase RecA from the DNA. The nucleotide-bound state of RecA determines the stability of its nucleoprotein filaments. Using single-molecule fluorescence approaches, we d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::170e134fc2bb9d63ae8d457ec44984be
https://doi.org/10.1093/nar/gks641
https://doi.org/10.1093/nar/gks641
Autor:
Matthew C. Swenson, Zygmunt Gryczynski, Clara L. Kielkopf, Karen R. Thickman, Joseph M. Kabogo
Publikováno v:
Journal of Molecular Biology. 356:664-683
Essential, protein-protein complexes between the large subunit of the U2 small nuclear RNA Auxiliary Factor (U2AF65) with the Splicing Factor 1 (SF1) or the spliceosomal component SF3b155 are exchanged during a critical, ATP-dependent step of pre-mRN
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4cc8b900003b94546715409a7e574255
https://doi.org/10.1016/j.jmb.2005.11.067
https://doi.org/10.1016/j.jmb.2005.11.067
Autor:
Dean E. Wilcox, Christopher J. Markworth, Fredrick J. Kull, Benjamin D. Malkin, Karen R. Thickman
Publikováno v:
Journal of Enzyme Inhibition. 16:135-145
The activity of potato polyphenol oxidase (tyrosinase) toward DL-3,4-dihydroxyphenylalanine (K(M) 5.39 mM) was studied using a variety of carboxylate buffers at a common pH and ionic strength. Enzyme activity, greatest in citrate and least in oxalate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4adbb3765a2e3d43219ee5ab45a204bf
https://doi.org/10.1080/14756360109162363
https://doi.org/10.1080/14756360109162363
Publikováno v:
Inorganic chemistry. 43(25)
The metal binding properties of peptides corresponding to metal-binding sites spanning regions that normally function as linkers in tandem arrays of metal-binding domain-containing proteins were examined. For a peptide with two His residues from one
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::796bad875714a41dbc06ffad23b193ab
https://pubmed.ncbi.nlm.nih.gov/15578823
https://pubmed.ncbi.nlm.nih.gov/15578823
Autor:
Wan-Pin Chang, Shinichi Takayama, Charles V. Clevenger, Winnie Ngo, Karen R. Thickman, John C. Reed
Publikováno v:
Molecular endocrinology (Baltimore, Md.). 11(5)
The expression and function of the newly identified Bcl-2- and Raf-1- binding protein, Bag-1, during the cytokine-regulated growth of B and T cell lines was examined. Immunoblot analysis of lysates from the interleukin-3 (IL-3)-dependent B cell line
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b2008b9426a32a2be0457478279c829d
https://pubmed.ncbi.nlm.nih.gov/9139804
https://pubmed.ncbi.nlm.nih.gov/9139804
Autor:
Matthew V. Fagerburg, Syam P. Anand, Grant D. Schauer, Saleem A. Khan, Karen R. Thickman, Sanford H. Leuba
Publikováno v:
Biophysical Journal. (3):591a
Using several experimental approaches, we are investigating the dynamics of individual PcrA DNA helicase interactions on DNA templates. Bulk biophysical and biochemical measurements are done in parallel to ascertain the viability and integrity of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6978ae231432bc9d6d63360d8f736e8
Publikováno v:
Biophysical Journal. (3):73a
Helicases are molecular motors that play critical roles in nucleic acid transactions, including replication, repair, recombination, and transcription. As observed in a number of diseases resulting from mutations in helicase genes, helicases are impor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3fbdf851f03ffa4ddb0a6e8795154db9