Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Karen R. Reeves"'
Autor:
Douglas E. Jorenby, John E. Pappas, Raymond Niaura, J. Taylor Hays, Frank T. Leone, Clare B. Billing, Karen R. Reeves, Kathryn E. Williams
Publikováno v:
Current Medical Research and Opinion. 24:1931-1941
To determine whether self-regulated flexible dosing with varenicline tartrate is safe and effective for smoking cessation.320 healthy, motivated-to-quit smokers (or =10 cigarettes/day) aged 18-65 years, entered a multicenter, randomized, double-blind
Autor:
Yoko Fujimoto, Taro Ishibashi, Akira Oshima, Masakazu Nakamura, Nami Maruyama, Karen R. Reeves
Publikováno v:
Clinical Therapeutics. 29:1040-1056
Varenicline, a selective alpha4beta2 nicotinic acetylcholine receptor partial agonist, has been developed specifically for smoking cessation. In Japan, 39.3% of men smoke and this is a major public health concern.The primary objective of this study w
Publikováno v:
Current Medical Research and Opinion. 23:793-801
We assessed the safety of long-term varenicline administration for smoking cessation.In this randomized, double-blind, multicenter trial, eligible adult smokers (18-75 years) who smoked an average ofor =10 cigarettes/day were randomized to either var
Autor:
J.J. Miceli, Karen R. Reeves, Watsky Eric Jacob, Neal R. Cutler, T. John Sramek, Michelle Middle, R.J. Anziano, Edmund P. Harrigan, Thomas Shiovitz
Publikováno v:
Journal of Clinical Psychopharmacology. 24:62-69
Many drugs have been associated with QTc prolongation and, in some cases, this is augmented by concomitant administration with metabolic inhibitors. The effects of 6 antipsychotics on the QTc interval at and around the time of estimated peak plasma/s
Publikováno v:
Psychopharmacology. 155:128-134
Rationale: Intramuscular (IM) conventional antipsychotics and/or benzodiazepines are effective in the short-term treatment of acutely agitated psychotic patients but may be associated with adverse effects. A short-acting IM formulation of the novel a
Publikováno v:
Journal of Clinical Psychopharmacology. 21:27-35
This study assessed the efficacy of ziprasidone for the treatment of schizoaffective disorder. Data were taken from subsets of patients with schizoaffective disorder, derived from two separate double-blind, placebo-controlled, parallel-group, multice
Autor:
David G. Daniel, Steven G. Potkin, Mani Lakshminarayanan, Karen R. Reeves, Edmund P. Harrigan, Dan L. Zimbroff
Publikováno v:
Neuropsychopharmacology. 20:491-505
In this double-blind study, patients with an acute exacerbation of schizophrenia or schizoaffective disorder were randomized to receive either ziprasidone 80 mg/day (n = 106) or 160 mg/day (n = 104) or placebo (n = 92), for 6 weeks. Both doses of zip
Autor:
Clare B. Billing, Jason Gong, John G. Spangler, Karen R. Reeves, A M Pennington, Kathryn E. Williams
Publikováno v:
Current Medical Research and Opinion. 24:577-579
Autor:
Karen R. Reeves, William H. Anderson
Publikováno v:
Administration and Policy in Mental Health. 18:205-208
Autor:
Clare B. Billing, Watsky Eric Jacob, Cheryl Oncken, Mitchell A. Nides, R.J. Anziano, Stephen I. Rennard, David Gonzales, Karen R. Reeves
Publikováno v:
Archives of internal medicine. 166(15)
The selective nicotinic acetylcholine receptor partial agonist, varenicline tartrate, represents a novel type of therapy for smoking cessation. This study evaluated the efficacy, safety, and tolerability of 4 varenicline dose regimens, 2 with progres