Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Karen Plant"'
Autor:
Ryan O. Snodgrass, Karan Govindpani, Karen Plant, Elisabeth C. Kugler, Changmin Doh, Thomas Dawson, Luis E. McCormack, Helen M. Arthur, Timothy J. A. Chico
Publikováno v:
Disease Models & Mechanisms, Vol 16, Iss 4 (2023)
Externí odkaz:
https://doaj.org/article/ee242943edf346f0a36a4522901556da
Autor:
Elisabeth Kugler, Ryan Snodgrass, George Bowley, Karen Plant, Jovana Serbanovic-Canic, Noémie Hamilton, Paul C Evans, Timothy Chico, Paul Armitage
Publikováno v:
Vascular Biology, Vol 3, Iss 1, Pp 1-16 (2021)
The role of blood flow in vascular development is complex and context-dependent. In this study, we quantify the effect of the lack of blood flow on embryonic vascular development on two vascular beds, namely the cerebral and trunk vasculature in zebr
Externí odkaz:
https://doaj.org/article/5accb5ba9bbe4e05ba735c616f0f73e1
Autor:
Alice Neal, Svanhild Nornes, Sophie Payne, Marsha D. Wallace, Martin Fritzsche, Pakavarin Louphrasitthiphol, Robert N. Wilkinson, Kira M. Chouliaras, Ke Liu, Karen Plant, Radhika Sholapurkar, Indrika Ratnayaka, Wiebke Herzog, Gareth Bond, Tim Chico, George Bou-Gharios, Sarah De Val
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-18 (2019)
The establishment of functional vasculatures requires the specification of newly formed vessels into veins and arteries. Here, Neal et al. use a combination of genetic approaches in mice and zebrafish to show that BMP signalling, via ALK3 and SMAD1/5
Externí odkaz:
https://doaj.org/article/10b6663419654c3aa3496b47db2a99e8
Autor:
Karishma Chhabria, Avgoustinos Vouros, Caroline Gray, Ryan B. MacDonald, Zhen Jiang, Robert Neil Wilkinson, Karen Plant, Eleni Vasilaki, Clare Howarth, Timothy J. A. Chico
Publikováno v:
Disease Models & Mechanisms, Vol 12, Iss 9 (2019)
Diabetes is associated with dysfunction of the neurovascular unit, although the mechanisms of this are incompletely understood and currently no treatment exists to prevent these negative effects. We previously found that the nitric oxide (NO) donor s
Externí odkaz:
https://doaj.org/article/eb6ba7eb9fea4bbeada40664c7fd4c91
Publikováno v:
Journal of Imaging, Vol 5, Iss 1, p 14 (2019)
Zebrafish have become an established in vivo vertebrate model to study cardiovascular development and disease. However, most published studies of the zebrafish vascular architecture rely on subjective visual assessment, rather than objective quantifi
Externí odkaz:
https://doaj.org/article/5ccc8f0ef00c45c59cb46703b2c77e91
Autor:
Peter Novodvorsky, Oliver Watson, Caroline Gray, Robert N Wilkinson, Scott Reeve, Carl Smythe, Richard Beniston, Karen Plant, Richard Maguire, Alexander M K Rothman, Stone Elworthy, Fredericus J M van Eeden, Timothy J A Chico
Publikováno v:
PLoS ONE, Vol 10, Iss 10, p e0141611 (2015)
Introduction and objectivesThe zinc-finger transcription factor Krϋppel-like factor 2 (KLF2) transduces blood flow into molecular signals responsible for a wide range of responses within the vasculature. KLF2 maintains a healthy, quiescent endotheli
Externí odkaz:
https://doaj.org/article/0b6fd4fb77374d14937538265e652a52
Publikováno v:
PLoS ONE, Vol 9, Iss 3, p e91855 (2014)
We have previously shown that the respiratory syncytial virus [RSV] can productively infect monocyte derived dendritic cells [MoDC] and remain dormant within the same cells for prolonged periods. It is therefore possible that infected dendritic cells
Externí odkaz:
https://doaj.org/article/2db8956e07494943a59584dad6a64dc8
Autor:
V. Peter Collins, Panayiota Poirazi, Tom C. Freeman, Lisa Happerfield, Karen Plant, Lu Liu, Matthew T. Wayland, Magnus Backlund, Anastasis Oulas, Lawrence P. Petalidis
Supplementary Information from Improved grading and survival prediction of human astrocytic brain tumors by artificial neural network analysis of gene expression microarray data
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0de832d1a251e2f8c8341cdba70999b7
https://doi.org/10.1158/1535-7163.22485644
https://doi.org/10.1158/1535-7163.22485644
Autor:
V. Peter Collins, Panayiota Poirazi, Tom C. Freeman, Lisa Happerfield, Karen Plant, Lu Liu, Matthew T. Wayland, Magnus Backlund, Anastasis Oulas, Lawrence P. Petalidis
Supplementary Table G from Improved grading and survival prediction of human astrocytic brain tumors by artificial neural network analysis of gene expression microarray data
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2216a9cb7c66ab20882cbf282b0804eb
https://doi.org/10.1158/1535-7163.22485635
https://doi.org/10.1158/1535-7163.22485635
Autor:
V. Peter Collins, Panayiota Poirazi, Tom C. Freeman, Lisa Happerfield, Karen Plant, Lu Liu, Matthew T. Wayland, Magnus Backlund, Anastasis Oulas, Lawrence P. Petalidis
Histopathologic grading of astrocytic tumors based on current WHO criteria offers a valuable but simplified representation of oncologic reality and is often insufficient to predict clinical outcome. In this study, we report a new astrocytic tumor mic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::817d2af3d321324c9974c20966ce6496
https://doi.org/10.1158/1535-7163.c.6532037
https://doi.org/10.1158/1535-7163.c.6532037