Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Karen Patricia Hartmann"'
Autor:
Florian Kast, Martin Schwill, Jakob C. Stüber, Svende Pfundstein, Gabriela Nagy-Davidescu, Josep M. Monné Rodríguez, Frauke Seehusen, Christian P. Richter, Annemarie Honegger, Karen Patricia Hartmann, Thomas G. Weber, Felix Kroener, Patrick Ernst, Jacob Piehler, Andreas Plückthun
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-18 (2021)
HER2 acts an oncogenic driver in numerous cancers. Here, the authors design an anti-HER2 biparatopic and tetravalent IgG fusion with inhibitory effects in a xenograft model.
Externí odkaz:
https://doaj.org/article/bbc4cba63fcc425a86335df0941f73d7
Autor:
Irene C. Schneider, Alexander Muik, Anke Muth, Christian J. Buchholz, Robert C. Münch, Karen Patricia Hartmann, Johanna Reul, Thorsten Friedel
Publikováno v:
Biomaterials. 144:84-94
We have established a novel approach for the covalent coupling of large polypeptides to the surface of fully assembled adeno-associated viral gene transfer vector (AAV) particles via split-intein mediated protein-trans-splicing (PTS). This way, we ac