Zobrazeno 1 - 10
of 65
pro vyhledávání: '"Karen P. McKinnon"'
Autor:
Wolfgang Beckabir, Mi Zhou, Jin Seok Lee, Steven P. Vensko, Mark G. Woodcock, Hsing-Hui Wang, Sara E. Wobker, Gatphan Atassi, Alec D. Wilkinson, Kenneth Fowler, Leah M. Flick, Jeffrey S. Damrauer, Michael R. Harrison, Karen P. McKinnon, Tracy L. Rose, Matthew I. Milowsky, Jonathan S. Serody, William Y. Kim, Benjamin G. Vincent
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract Neoadjuvant cisplatin-based chemotherapy is standard of care for muscle-invasive bladder cancer (MIBC). Immune checkpoint inhibition (ICI) alone, and ICI in combination with chemotherapy, have demonstrated promising pathologic response (
Externí odkaz:
https://doaj.org/article/20a284baf2454780aedd68c631ea83b7
Autor:
Isla R. Simpson, David M. Lawrence, Sean C. Swenson, Cecile Hannay, Karen A. McKinnon, John E. Truesdale
Publikováno v:
Journal of Advances in Modeling Earth Systems, Vol 14, Iss 4, Pp n/a-n/a (2022)
Abstract The Community Earth System Model (CESM) is widely used for the prediction and understanding of climate variability and change. Accurate simulation of the behavior of near surface air temperature (T2m) is critical in such a model for addressi
Externí odkaz:
https://doaj.org/article/abbfb1f3867d426f828cb63739b58e3c
Publikováno v:
Earth's Future, Vol 8, Iss 10, Pp n/a-n/a (2020)
Abstract The origins of uncertainty in climate projections have major consequences for the scientific and policy decisions made in response to climate change. Internal climate variability, for example, is an inherent uncertainty in the climate system
Externí odkaz:
https://doaj.org/article/c7c1077c368b4286bd5adc14e5cb6509
Autor:
Benjamin G. Vincent, Danielle M. File, Karen P. McKinnon, Dominic T. Moore, Jeffrey A. Frelinger, Edward J. Collins, Joseph G. Ibrahim, Lisa Bixby, Shannon Reisdorf, Sonia J. Laurie, Yara A. Park, Carey K. Anders, Frances A. Collichio, Hyman B. Muss, Lisa A. Carey, Hendrik W. van Deventer, E. Claire Dees, Jonathan S. Serody
Publikováno v:
J Immunol
Previous work from our group and others has shown that patients with breast cancer can generate a T cell response against specific human epidermal growth factor 2 (HER2) epitopes. In addition, preclinical work has shown that this T cell response can
Autor:
Benjamin G. Vincent, Bhishamjit S. Chera, Jessica R. Bauman, Mark Christian Weissler, Hsing-Hui Wang, Karen P. McKinnon, Ranee Mehra, Christopher Hilliard, D. Neil Hayes, Colette J. Shen, Adam M. Zanation, Shetal Patel, Thomas J. Galloway, Jeffrey M. Blumberg, Trevor G. Hackman, Samip Patel, Juneko E. Grilley Olson, Allision M. Deal, Siddharth Sheth, Jared Weiss
Cytokines and Chemokines
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6394fb18038ddc6fe4937b620e829f09
https://doi.org/10.1158/1078-0432.22637393.v1
https://doi.org/10.1158/1078-0432.22637393.v1
Autor:
Ivana Gojo, Jonathan S. Serody, Leo Luznik, Nathan D. Montgomery, Mark J. Levis, B. Douglas Smith, Amy E. DeZern, Gabrielle T. Prince, Jonathan A. Webster, Hendrik Van Deventer, Katarzyna Jamieson, Catherine C. Coombs, Matthew C. Foster, Hanna A. Knaus, Francesco Mazziotta, Rupkatha Mukhopadhyay, Alec D. Wilkinson, Karen P. McKinnon, Dominic Moore, Anastasia Ivanova, Benjamin G. Vincent, Joshua F. Zeidner
Supplemental Methods
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::574ae48df49e97c2a4bc9c7170265627
https://doi.org/10.1158/2643-3230.22543396.v1
https://doi.org/10.1158/2643-3230.22543396.v1
Autor:
Ivana Gojo, Jonathan S. Serody, Leo Luznik, Nathan D. Montgomery, Mark J. Levis, B. Douglas Smith, Amy E. DeZern, Gabrielle T. Prince, Jonathan A. Webster, Hendrik Van Deventer, Katarzyna Jamieson, Catherine C. Coombs, Matthew C. Foster, Hanna A. Knaus, Francesco Mazziotta, Rupkatha Mukhopadhyay, Alec D. Wilkinson, Karen P. McKinnon, Dominic Moore, Anastasia Ivanova, Benjamin G. Vincent, Joshua F. Zeidner
Immune suppression, exhaustion, and senescence are frequently seen throughout disease progression in acute myeloid leukemia (AML). We conducted a phase II study of high-dose cytarabine followed by pembrolizumab 200 mg i.v. on day 14 to examine whethe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6004747874b06d9a5b1ad6a2d8771e7d
https://doi.org/10.1158/2643-3230.c.6550243
https://doi.org/10.1158/2643-3230.c.6550243
Autor:
Paul M. Armistead, Gary L. Glish, Jeffrey A. Frelinger, Adam S. Buntzman, Gregory Lizée, Tania Rodriguez-Cruz, Gheath Alatrash, Jonathan S. Serody, Thomas C. Shea, Stefanie Sarantopoulos, Don A. Gabriel, William A. Wood, James M. Coghill, Patricia A. Ropp, Lisa M. Bixby, Karen P. McKinnon, Jennifer P. Waugh, Atim A. Enyenihi, Benjamin G. Vincent, Colleen S. McGary, Sally A. Hunsucker
Testing of T cell–based cancer therapeutics often involves measuring cancer antigen–specific T-cell populations with the assumption that they arise from in vivo clonal expansion. This analysis, using peptide/MHC tetramers, is often ambiguous. Fro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3eec4adfdb57bd346edb8738aeab5e77
https://doi.org/10.1158/2326-6066.c.6548852
https://doi.org/10.1158/2326-6066.c.6548852
Autor:
Paul M. Armistead, Gary L. Glish, Jeffrey A. Frelinger, Adam S. Buntzman, Gregory Lizée, Tania Rodriguez-Cruz, Gheath Alatrash, Jonathan S. Serody, Thomas C. Shea, Stefanie Sarantopoulos, Don A. Gabriel, William A. Wood, James M. Coghill, Patricia A. Ropp, Lisa M. Bixby, Karen P. McKinnon, Jennifer P. Waugh, Atim A. Enyenihi, Benjamin G. Vincent, Colleen S. McGary, Sally A. Hunsucker
The document contains 4 supplemental tables: 1. RT-PCR Primers for TCRbeta sequencing 2. HPLC-MS identified peptide sequences 3. The amino acid sequences of recurrent TCRbeta clonotypes 4. The distribution of the CDR3 amino acid length in the analyze
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::648b7e1f8ff382184c18cd326a952589
https://doi.org/10.1158/2326-6066.22538669.v1
https://doi.org/10.1158/2326-6066.22538669.v1
Autor:
Benjamin G. Vincent, Bhishamjit S. Chera, Jessica R. Bauman, Mark Christian Weissler, Hsing-Hui Wang, Karen P. McKinnon, Ranee Mehra, Christopher Hilliard, D. Neil Hayes, Colette J. Shen, Adam M. Zanation, Shetal Patel, Thomas J. Galloway, Jeffrey M. Blumberg, Trevor G. Hackman, Samip Patel, Juneko E. Grilley Olson, Allison M. Deal, Siddharth Sheth, Jared Weiss
Purpose:Although cisplatin plus radiotherapy is a standard treatment of locally advanced head and neck squamous cell carcinoma (LA-HNSCC), cisplatin contraindication is common. Radiation elicits and promotes tumor-directed immune stimulation, which m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79c80da7f51cb6f8611a8b2d244eab44
https://doi.org/10.1158/1078-0432.c.6529367.v1
https://doi.org/10.1158/1078-0432.c.6529367.v1