Zobrazeno 1 - 10
of 49
pro vyhledávání: '"Karen Newell Rogers"'
Autor:
Jaclyn Iannucci, Reagan Dominy, Shreya Bandopadhyay, E. Madison Arthur, Brenda Noarbe, Amandine Jullienne, Margret Krkasharyan, Richard P. Tobin, Aleksandr Pereverzev, Samantha Beevers, Lavanya Venkatasamy, Karienn A. Souza, Daniel C. Jupiter, Alan Dabney, Andre Obenaus, M. Karen Newell-Rogers, Lee A. Shapiro
Publikováno v:
Journal of Neuroinflammation, Vol 21, Iss 1, Pp 1-24 (2024)
Abstract Background Traumatic brain injury (TBI) is a significant risk factor for Alzheimer’s disease (AD), and accumulating evidence supports a role for adaptive immune B and T cells in both TBI and AD pathogenesis. We previously identified B cell
Externí odkaz:
https://doaj.org/article/7fbfabe044294bf4bcec2f591179eada
Autor:
Ali Divan, Timothy Casselli, S Anand Narayanan, Sanjib Mukherjee, David C Zawieja, John A Watt, Catherine A Brissette, M Karen Newell-Rogers
Publikováno v:
PLoS ONE, Vol 13, Iss 5, p e0196893 (2018)
Borrelia burgdorferi, the causative agent of Lyme disease, is a vector-borne bacterial infection that is transmitted through the bite of an infected tick. If not treated with antibiotics during the early stages of infection, disseminated infection ca
Externí odkaz:
https://doaj.org/article/af9db701189d4e6eb01083ae2b578e1e
Publikováno v:
Alzheimer's & Dementia. 18
Autor:
M. Karen Newell-Rogers, Amanda Duong, Rizwan Nazarali, Richard P. Tobin, Susannah K. Rogers, Lee A. Shapiro
Publikováno v:
International journal of molecular sciences. 23(17)
TBI induces splenic B and T cell expansion that contributes to neuroinflammation and neurodegeneration. The vagus nerve, the longest of the cranial nerves, is the predominant parasympathetic pathway allowing the central nervous system (CNS) control o
Autor:
Omar K. Danner, Leslie R. Matthews, Sharon Francis, Veena N. Rao, Cassie P. Harvey, Richard P. Tobin, Ken L. Wilson, Ernest Alema-Mensah, M. Karen Newell Rogers, Ed W. Childs
Publikováno v:
Journal of Nutrition and Metabolism, Vol 2016 (2016)
Class II invariant chain peptide (CLIP) expression has been demonstrated to play a pivotal role in the regulation of B cell function after nonspecific polyclonal expansion. Several studies have shown vitamin D3 helps regulate the immune response. We
Externí odkaz:
https://doaj.org/article/cbc3c09f9ab841e881656ce680930446
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 2 (2015)
The maternal innate immune system plays an important role both in normal pregnancy as well as hypertensive disorders of pregnancy including preeclampsia (PE). We propose 4 pathways that involve excessive innate immunity that lead to most forms of PE.
Externí odkaz:
https://doaj.org/article/87b13e02a78d4023b66da1ff14365a59
Autor:
Ekokobe Fonkem, Karen newell Rogers, Richard Tobin, Mita Das, Sara Bowen, Ramya Tadipatri, Debbie Healey, Christopher Quarles, John Clark
Publikováno v:
Neuro-Oncology. 24:vii95-vii95
Hurdles to effective treatments for glioblastoma multiforme (GBM), the most aggressive form of brain cancer, are resistance to chemotherapy, radiation, and immune checkpoint inhibitors. GBMs, like other “difficult to treat” tumors, often over-uti
Autor:
Ottis Scrivner, Long Dao, M Karen Newell-Rogers, Babbak Shahandeh, Frank L Meyskens, Susan Kurumi Kozawa, Feng Liu-Smith, Germán Plascencia-Villa, Miguel José-Yacamán, Shang Jia, Christopher J Chang, Patrick J Farmer
Publikováno v:
Metallomics
Metallomics : integrated biometal science, vol 14, iss 1
Metallomics : integrated biometal science, vol 14, iss 1
In this report, we investigate the toxicity of the ionophore thiomaltol (Htma) and Cu salts to melanoma. Divalent metal complexes of thiomaltol display toxicity against A375 melanoma cell culture resulting in a distinct apoptotic response at submicro
Autor:
Olalekan Olanipekun, M Karen Newell Rogers, Janice Oh, Ekokobe Fonkem, Solomon Ambe, Nduma N Basil, Kristopher A. Lyon
Publikováno v:
Cureus
Background Differences among the top five races in Texas will be explored to determine if racial, geographic, and healthcare disparities exist in patients undergoing treatment for a primary malignant brain tumor. Methods Data were obtained from the T
Autor:
Ekokobe Fonkem, M. Karen Newell-Rogers, Richard Tobin, Debbie Healey, Mita Das, Sara Bowen, Chad Quarles, John Clark
Publikováno v:
Cancer Research. 82:LB136-LB136
The purpose of this study was to test the effects of a novel small molecule inhibitor of phosphatidylinositol-3 kinase (PI3K) for the treatment of glioblastoma multiforme (GBM). The key hurdles to effective treatment for GBM, the “most deadly” fo