Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Karen Mochoruk"'
Autor:
Landon Pastushok, Shrutii Sarda, Karen Mochoruk, Wayne Hill, Loni T. Pickle, Michelle Toro, Carolina Gonzalez, Stephanie Ostresh, Timothy J. Looney, Chenchen Yang, Julie Stakiw, Mark J. Bosch, Hadi Goubran, C. Ronald Geyer, Geoffrey M. Lowman, John F. DeCoteau
Publikováno v:
Journal of Molecular Pathology, Vol 5, Iss 1, Pp 45-65 (2024)
B-cell neoplasms possess clonal B-cell receptor rearrangements (BCR clonotype lineages) that can be identified by sequencing the B-cell repertoire for use in diagnostics, risk stratification, and high-sensitivity monitoring. BCR somatic hypermutation
Externí odkaz:
https://doaj.org/article/da7a5fbbb6434fb9a56fc2e46e4e3bc9
Autor:
Kimberly A. Jett, Zakery N. Baker, Amzad Hossain, Aren Boulet, Paul A. Cobine, Sagnika Ghosh, Philip Ng, Orhan Yilmaz, Kris Barreto, John DeCoteau, Karen Mochoruk, George N. Ioannou, Christopher Savard, Sai Yuan, Osama H.M.H. Abdalla, Christopher Lowden, Byung-Eun Kim, Hai-Ying Mary Cheng, Brendan J. Battersby, Vishal M. Gohil, Scot C. Leary
Publikováno v:
The Journal of Clinical Investigation, Vol 133, Iss 1 (2023)
Signaling circuits crucial to systemic physiology are widespread, yet uncovering their molecular underpinnings remains a barrier to understanding the etiology of many metabolic disorders. Here, we identified a copper-linked signaling circuit activate
Externí odkaz:
https://doaj.org/article/018c1e9c28eb4a92a02a5abcb7afd106
Autor:
Geoffrey Marc Lowman, Landon Pastushok, Karen Mochoruk, Wayne Hill, Michelle Toro, Loni Pickle, Carolina Gonzalez, Stephanie Ostresh, Shrutii Sarda, Chenchen Yang, Julie Stakiw, Mark Bosch, Hadi Goubran, Ron Geyer, John DeCoteau
Publikováno v:
Cancer Research. 82:2293-2293
Introduction: B cell repertoire analysis by next-generation sequencing (NGS) is at the forefront of leukemia and lymphoma research. Some advantages provided by NGS-based techniques include a lower limit-of-detection and simpler paths to standardizati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::146d7364280d983c52ee121eb8c3b74c
https://doi.org/10.1158/1538-7445.am2022-2293
https://doi.org/10.1158/1538-7445.am2022-2293
Autor:
Ronald Geyer, Shrutii Sarda, Wayne Hill, Stephanie Ostresh, Julie Stakiw, Carolina Gonzalez, Mark Bosch, Geoffrey Lowman, John F. DeCoteau, Landon Pastushok, Loni Pickle, Hadi Goubran, Michelle Toro, Karen Mochoruk, Chenchen Yang
Publikováno v:
Blood. 138:1881-1881
Introduction B cell repertoire analysis by next-generation sequencing (NGS) is at the forefront of leukemia and lymphoma research. Some advantages provided by NGS-based techniques include a lower limit-of-detection and simpler paths to standardizatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bfb70552f553e17d8997c31b1dbc3df7
https://doi.org/10.1182/blood-2021-152987
https://doi.org/10.1182/blood-2021-152987
Publikováno v:
Blood. 124:4519-4519
Chronic myelogenous leukemia (CML) is maintained by a minor population of leukemic stem cells (LSCs) that exhibit innate resistance to tyrosine kinase inhibitors (TKIs) targeting BCR-ABL. Innate resistance can be induced by cytokines and growth facto
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4347ce2a1936d814f3730ac1e6a07a37
https://doi.org/10.1182/blood.v124.21.4519.4519
https://doi.org/10.1182/blood.v124.21.4519.4519
Publikováno v:
Blood. 124:4517-4517
Chronic myelogenous leukemia (CML) is maintained by a minor population of leukemic stem cells (LSCs) that exhibit innate resistance to tyrosine kinase inhibitors (TKIs) targeting BCR-ABL. Innate resistance can be induced by cytokines and growth facto
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f66b781b1f9f35f7f8159ad46aeeceae
https://doi.org/10.1182/blood.v124.21.4517.4517
https://doi.org/10.1182/blood.v124.21.4517.4517