Zobrazeno 1 - 10
of 202
pro vyhledávání: '"Karen McLean"'
Autor:
Julien Leuenberger, Sanjeev Kumar Sharma, Karen McLean, Roland Pellé, Aurélie Bérard, Marie-Laure Lesage, Danièle Porhel, Marie-Ange Dantec, Jean-Eric Chauvin, Glenn J. Bryan, Marie-Laure Pilet-Nayel, Marie-Claire Kerlan, Florence Esnault
Publikováno v:
Frontiers in Plant Science, Vol 15 (2024)
Externí odkaz:
https://doaj.org/article/b4868ae386594a2da6162227d570e7aa
Publikováno v:
Gynecologic Oncology Reports, Vol 48, Iss , Pp 101217- (2023)
Externí odkaz:
https://doaj.org/article/8735f674857245a49038c9c6bbc7ef46
Autor:
Minh Tung Phung, Pham Le An, Nguyen Nhu Vinh, Hong H T C Le, Karen McLean, Rafael Meza, Bhramar Mukherjee, Alice W Lee, Celeste Leigh Pearce
Publikováno v:
PLOS Global Public Health, Vol 3, Iss 6, p e0001817 (2023)
Cervical cancer is the second most common gynecologic cancer in Vietnam but based on the literature, only ~25% of Vietnamese women reported ever being screened for cervical cancer. To inform strategies to reduce the cervical cancer burden in Southern
Externí odkaz:
https://doaj.org/article/3cdef82ab2f945c6b91df01f8d0f961c
Autor:
Lan G. Coffman, Taylor J. Orellana, Tianshi Liu, Leonard G. Frisbie, Daniel Normolle, Kent Griffith, Shitanshu Uppal, Karen McLean, Jessica Berger, Michelle Boisen, Madeleine Courtney-Brooks, Robert P. Edwards, Jamie Lesnock, Haider Mahdi, Alexander Olawaiye, Paniti Sukumvanich, Sarah E. Taylor, Ronald Buckanovich
Publikováno v:
JCI Insight, Vol 7, Iss 18 (2022)
BACKGROUND New therapeutic combinations to improve outcomes of patients with ovarian cancer are clearly needed. Preclinical studies with ribociclib (LEE-011), a CDK4/6 cell cycle checkpoint inhibitor, demonstrate a synergistic effect with platinum ch
Externí odkaz:
https://doaj.org/article/0e91eac13b934298960720568bddbce7
Autor:
Caitlin A. Schonewolf, MD, MSCTS, Elizabeth M. Jaworski, MD, Steven G. Allen, MD, PhD, Karen McLean, MD, Christopher D. Lao, MD, Lynn M. Schuchter, MD, Janos Tanyi, MD, PhD, Neil K. Taunk, MD, MSCTS
Publikováno v:
Advances in Radiation Oncology, Vol 7, Iss 2, Pp 100839- (2022)
Externí odkaz:
https://doaj.org/article/ee581f623dc4407fa1f8f67bd9f2e6e0
Autor:
James J. Newham, Karen McLean, Samuel Ginja, Lisa Hurt, Carly Molloy, Raghu Lingam, Sharon Goldfeld
Publikováno v:
BMC Public Health, Vol 20, Iss 1, Pp 1-16 (2020)
Abstract Background Universal child health services (UCHS) provide an important pragmatic platform for the delivery of universal and targeted interventions to support families and optimize child health outcomes. We aimed to identify brief, evidence-b
Externí odkaz:
https://doaj.org/article/beb2b3ea10ca4a8aa89c492708797014
Autor:
Lijun Tan, Katelyn Tondo-Steele, Caroline Foster, Carrie McIlwain, Danielle E. Bolland, Howard C. Crawford, Andrew Sciallis, Karen McLean
Publikováno v:
Cancers, Vol 14, Iss 19, p 4675 (2022)
Antiestrogen therapy (AET) is an alternative to cytotoxic chemotherapy for recurrent ovarian cancer, yet the often short duration of response suggests mechanisms of resistance. We previously demonstrated that tumor microenvironment interleukin-6/leuk
Externí odkaz:
https://doaj.org/article/d5eca5c87b274408a21398e310e91040
Autor:
Katelyn Tondo-Steele, Karen McLean
Publikováno v:
Cancers, Vol 14, Iss 19, p 4696 (2022)
The objective of this review is to explore the metabolomic environment of epithelial ovarian cancer that contributes to chemoresistance and to use this knowledge to identify possible targets for therapeutic intervention. The Warburg effect describes
Externí odkaz:
https://doaj.org/article/bd18137cc9b84e8baed024791e1234ad
Autor:
Kari E Hacker, Danielle E Bolland, Lijun Tan, Anjan K Saha, Yashar S Niknafs, David M Markovitz, Karen McLean
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 20, Iss 12, Pp 1209-1218 (2018)
DNA damage repair alterations play a critical role in ovarian cancer tumorigenesis. Mechanistic drivers of the DNA damage response consequently present opportunities for therapeutic targeting. The chromatin-binding DEK oncoprotein functions in DNA do
Externí odkaz:
https://doaj.org/article/32897ee09bdf49fea7db06aafbb9c0bc
Linkage Disequilibrium and Evaluation of Genome-Wide Association Mapping Models in Tetraploid Potato
Autor:
Sanjeev Kumar Sharma, Katrin MacKenzie, Karen McLean, Finlay Dale, Steve Daniels, Glenn J. Bryan
Publikováno v:
G3: Genes, Genomes, Genetics, Vol 8, Iss 10, Pp 3185-3202 (2018)
Genome-wide association studies (GWAS) have become a powerful tool for analyzing complex traits in crop plants. The current study evaluates the efficacy of various GWAS models and methods for elucidating population structure in potato. The presence o
Externí odkaz:
https://doaj.org/article/9da4c50f777e4a4986d9a77227ab94b8