Zobrazeno 1 - 10
of 93
pro vyhledávání: '"Karen M. Vernau"'
Autor:
Anna M. Massie, Katherine Skorupski, William Vernau, Ehren McLarty, Rachel V. Brady, Karen M. Vernau
Publikováno v:
Journal of Veterinary Internal Medicine, Vol 37, Iss 6, Pp 2492-2497 (2023)
Abstract A 3‐year‐old male pit bull terrier was presented for a 4‐day history of progressive tetraparesis and cervical pain. Magnetic resonance imaging confirmed an extradural mass within the left lateral vertebral canal extending from caudal C
Externí odkaz:
https://doaj.org/article/5b567bb5c6594bb28ccae55eb2550cf6
Autor:
Danielle M. Zwueste, Karen M. Vernau, William Vernau, Bruno H. Pypendop, Heather K. Knych, Carlos A. Rodrigues, Amir Kol, Maria Questa, Peter J. Dickinson
Publikováno v:
Journal of Veterinary Internal Medicine, Vol 37, Iss 6, Pp 2429-2442 (2023)
Abstract Background Cytosine arabinoside (Ara‐C) is a nucleoside analog prodrug utilized for immunomodulatory effects mediated by its active metabolite Ara‐CTP. Optimal dosing protocols for immunomodulation in dogs have not been defined. Cytarabi
Externí odkaz:
https://doaj.org/article/79a62cc71e4141b481770e15f2321627
Autor:
Ryan G. Toedebusch, Ning-Wei Wei, Kulani T. Simafranca, Jennie A. Furth-Jacobus, Ingrid Brust-Mascher, Susan L. Stewart, Peter J. Dickinson, Kevin D. Woolard, Chai-Fei Li, Karen M. Vernau, Frederick J. Meyers, Christine M. Toedebusch
Publikováno v:
Veterinary Sciences, Vol 10, Iss 6, p 403 (2023)
The goal of this study was to define the glioma-associated microglia/macrophage (GAM) response and associated molecular landscape in canine oligodendrogliomas. Here, we quantified the intratumoral GAM density of low- and high-grade oligodendrogliomas
Externí odkaz:
https://doaj.org/article/97c566617d9141369779ee58f885c55f
Autor:
Yu Ueda, Ronald H. L. Li, Nghi Nguyen, Eric S. Ontiveros, Samantha L. Kovacs, Maureen S. Oldach, Karen M. Vernau, Michael H. Court, Joshua A. Stern
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Abstract Clopidogrel is converted to its active metabolite by cytochrome P450 isoenzymes and irreversibly inhibits platelet activation by antagonizing the adenosine-diphosphate (ADP) receptor. It is frequently used in cats with hypertrophic cardiomyo
Externí odkaz:
https://doaj.org/article/ddb2a51e34504216b33792c1c628f25d
Autor:
Alana R. Rodney, Reuben M. Buckley, Robert S. Fulton, Catrina Fronick, Todd Richmond, Christopher R. Helps, Peter Pantke, Dianne J. Trent, Karen M. Vernau, John S. Munday, Andrew C. Lewin, Rondo Middleton, Leslie A. Lyons, Wesley C. Warren
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Abstract Over 94 million domestic cats are susceptible to cancers and other common and rare diseases. Whole exome sequencing (WES) is a proven strategy to study these disease-causing variants. Presented is a 35.7 Mb exome capture design based on the
Externí odkaz:
https://doaj.org/article/e18ff08359a64385b50b033630e617e2
Autor:
Kayla M. Fowler, Timothy A. Bolton, John H. Rossmeisl, Avril U. Arendse, Karen M. Vernau, Ronald H. L. Li, Rell L. Parker
Publikováno v:
Frontiers in Veterinary Science, Vol 9 (2022)
Three juvenile dogs presented with an acute onset of paraspinal hyperesthesia and/or neurologic deficits. These dogs underwent anesthesia for MRI and additional diagnostics. The thoracolumbar MRI in Dog 1 revealed an accumulation of T2-weighted (T2W)
Externí odkaz:
https://doaj.org/article/22356ddc4dad481196b735ed22664baf
Autor:
Peter J. Dickinson, Michael Bannasch, Sara M. Thomasy, Vishal D. Murthy, Karen M. Vernau, Molly Liepnieks, Elizabeth Montgomery, Kelly E. Knickelbein, Brian Murphy, Niels C. Pedersen
Publikováno v:
Journal of Veterinary Internal Medicine, Vol 34, Iss 4, Pp 1587-1593 (2020)
Abstract Feline infectious peritonitis (FIP) is caused by a mutant biotype of the feline enteric coronavirus. The resulting FIP virus (FIPV) commonly causes central nervous system (CNS) and ocular pathology in cases of noneffusive disease. Over 95% o
Externí odkaz:
https://doaj.org/article/da216336e1b044758875a91d5f2c82f1
Autor:
Izumi Toyoda, William Vernau, Beverly K. Sturges, Karen M. Vernau, John Rossmeisl, Kurt Zimmerman, Chelsea M. Crowe, Kevin Woolard, Michelle Giuffrida, Robert J. Higgins, Peter J. Dickinson
Publikováno v:
Journal of Veterinary Internal Medicine, Vol 34, Iss 2, Pp 828-837 (2020)
Abstract Background Histiocytic sarcoma affecting the central nervous system (CNS HS) in dogs may present as primary or disseminated disease, often characterized by inflammation. Prognosis is poor, and imaging differentiation from other CNS tumors ca
Externí odkaz:
https://doaj.org/article/7048d89df2ce4245aec3c14ff549b82a
Autor:
Kate L. Tsai, Karen M. Vernau, Kathryn Winger, Danielle M. Zwueste, Beverly K. Sturges, Marguerite Knipe, D. Colette Williams, Kendall J. Anderson, Jacquelyn M. Evans, Ling T. Guo, Leigh Anne Clark, G. Diane Shelton
Publikováno v:
Journal of Veterinary Internal Medicine, Vol 34, Iss 1, Pp 258-265 (2020)
Abstract Background Congenital myasthenic syndromes (CMSs) are a group of inherited disorders of neuromuscular transmission that may be presynaptic, synaptic, or postsynaptic. Causative mutations have been identified in 4 breeds including the Labrado
Externí odkaz:
https://doaj.org/article/056a302811af4ded8f6e77fc3ea79e06
Autor:
Toedebusch, Ryan G. Toedebusch, Ning-Wei Wei, Kulani T. Simafranca, Jennie A. Furth-Jacobus, Ingrid Brust-Mascher, Susan L. Stewart, Peter J. Dickinson, Kevin D. Woolard, Chai-Fei Li, Karen M. Vernau, Frederick J. Meyers, Christine M.
Publikováno v:
Veterinary Sciences; Volume 10; Issue 6; Pages: 403
The goal of this study was to define the glioma-associated microglia/macrophage (GAM) response and associated molecular landscape in canine oligodendrogliomas. Here, we quantified the intratumoral GAM density of low- and high-grade oligodendrogliomas