Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Karen M. Ricketts"'
Autor:
Richard E. Sweeney, Michael C. Babin, Robyn B. Lee, Karen M. Ricketts, Michele Y. Gazaway, John J. Brozetti
Publikováno v:
Journal of Toxicology: Cutaneous and Ocular Toxicology. 23:65-75
The eye is considered to be one of the most sensitive organs to sulfur mustard [bis(2‐chloroethyl) sulfide (SM)], with injuries ranging from mild conjunctivitis to advanced corneal disease. Even mild ocular involvement from sulfur mustard exposure
Autor:
Aharon Levy, M. Ross, Michael C. Babin, J. Brozetti, J. Turetz, Adina Amir, T. Logan, Karen M. Ricketts, Shira Chapman, Tamar Kadar
Publikováno v:
Journal of Toxicology: Cutaneous and Ocular Toxicology. 22:201-214
Sulfur mustard (2,2‐dichlorodiethyl sulfide; HD), is a potent alkylating agent which in liquid or vapor form is capable of causing severe injuries to skin and respiratory tract, and was shown to cause short‐ and long‐term ocular injuries. N‐A
Autor:
Michael Shutz, Thomas P. Logan, Roy Railer, Robert P. Casillas, Susan M. Schulz, Karen M. Ricketts
Publikováno v:
Toxicology Mechanisms and Methods. 12:293-300
The CD1-haired mouse and the SKH-hairless mouse are two animal models that have been used to evaluate sulfur mustard (HD) exposure and protection in our laboratory. In a recent study we observed that a substance P inhibitor protected the haired mouse
Autor:
Larry W. Mitcheltree, Robert P. Casillas, M. Y. Gazaway, Michael C. Babin, Karen M. Ricketts, J. P. Skvorak
Publikováno v:
Journal of Applied Toxicology. 20:S141-S144
The mouse ear vesicant model (MEVM) provides a quantitative edema response as well as histopathological and biochemical endpoints as measurements of inflammation and tissue damage following exposure to the chemical warfare agent sulfur mustard (HD).
Publikováno v:
Journal of Applied Toxicology. 20:S177-S182
Tissue homogenates from mouse ear skin exposed to sulfur mustard (HD, which is a military designation and probably originated from a World War I slang term 'Hun Stuff') were assayed for serine and cysteine protease activities. Enzyme activity was mea
Autor:
James A. Blank, Robert P. Casillas, Larry W. Mitcheltree, Al W. Singer, Karen M. Ricketts, Jean A. Truxall, Robyn C. Kiser, Nancy A. Niemuth, Lilia R. Castrejon, Shawn M. Shumaker
Publikováno v:
Journal of Applied Toxicology. 20:S145-S151
The mouse ear edema model is recognized for its usefulness in studying skin responses and damage following exposure to chemical irritants, and for evaluating pharmacological agents against chemically induced skin injury. We recently modified the mous
Autor:
Carol L. K. Sabourin, Robert P. Casillas, Jamie L. Martin, Michael C. Babin, Mindy K. Stonerock, James V. Rogers, Stacy L. Casbohm, Karen M. Ricketts-Kaminsky
Publikováno v:
Toxicology. 204(2-3)
Sulfur mustard [bis(2-chloroethyl)sulfide; SM] is a chemical warfare agent that produces edema and blister formation with a severe inflammatory reaction. The mouse ear vesicant model for SM injury has been used to evaluate pharmacological agents for