Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Karen M. Kumor"'
Autor:
Nicola G. Cascella, Daniel Walter, Karen M. Kumor, Craig T. Nagoshi, Charles Muntaner, Charles A. Haertzen
Publikováno v:
Journal of Substance Abuse. 6:355-366
Cardiovascular and subjective responses to placebo and 40-mg intravenous (iv) cocaine injections were measured in 29 male iv cocaine users: most subjects received each of these injections on two separate occasions. Most of the subjects also completed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06dc05387002707d9868d417cce79a7f
https://doi.org/10.1016/s0899-3289(94)90278-x
https://doi.org/10.1016/s0899-3289(94)90278-x
Autor:
Dennis A Noe, Karen M Kumor
Publikováno v:
Clinical Pharmacology and Therapeutics. 49:426-432
We developed a pharmacokinetic-pharmacodynamic model of the heart rate response to cocaine consisting of the sum of the baseline heart rate, a chronotropic drug effect, and a conditioned heart rate response. The conditioned response was modeled as ha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d37c482a9bd11c9f0c4e9b0530a4c2e8
https://doi.org/10.1038/clpt.1991.50
https://doi.org/10.1038/clpt.1991.50
Publikováno v:
Pharmacology Biochemistry and Behavior. 35:397-404
Profiles of the subjective and physiological effects of opioid drugs in man cannot be assigned with precision to specific opioid drug-receptor interactions. We administered a set of training doses of ketocyclacine, morphine, cyclazocine, naloxone and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d0e7c1d79851640e53db1915282404d2
https://doi.org/10.1016/0091-3057(90)90176-i
https://doi.org/10.1016/0091-3057(90)90176-i
Publikováno v:
Psychopharmacology. 105(1)
The effects of oral nifedipine pretreatment on subjective and cardiovascular responses to intravenous cocaine infusions were studied in cocaine-using volunteers. Nifedipine, 10 mg or placebo, was administered 20-25 min before placebo, 20 mg, or 40 mg
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e4b0004c5093a4cd219724a9dfd14e9
https://pubmed.ncbi.nlm.nih.gov/1745709
https://pubmed.ncbi.nlm.nih.gov/1745709
Publikováno v:
Psychiatry Research. 27:117-125
We examined the effect of the dopaminergic blocking agent, haloperidol, on the subjective and physiologic response to cocaine in cocaine-using volunteers. Five subjects received cocaine (40 mg) or placebo administered intravenously 20 min following p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a6d75c1a85a5eef075a364ba5f7fc7d4
https://doi.org/10.1016/0165-1781(89)90127-3
https://doi.org/10.1016/0165-1781(89)90127-3
Publikováno v:
Developmental Pharmacology and Therapeutics. 7:368-376
17 children with serious infections were treated for an average period of 9.5 days with 420 mg/m2/dose of amikacin every 8 h. The nephrotoxicity and ototoxicity of this 'high-dose' regimen was studied. None of the children had evidence of nephrotoxic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55633bfa0e0de9c08390299d9b83beab
https://doi.org/10.1159/000457188
https://doi.org/10.1159/000457188
Publikováno v:
Journal of Chromatography B: Biomedical Sciences and Applications. 383:158-165
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e2ae79a1c452f65301390142516f5b45
https://doi.org/10.1016/s0378-4347(00)83455-6
https://doi.org/10.1016/s0378-4347(00)83455-6
Publikováno v:
Psychopharmacology. 97:59-64
In nine experienced users of cocaine, we examined the urge to use cocaine or other drugs following a 40 mg dose of intravenous (IV) cocaine with and without oral pretreatment with 2.5 mg bromocriptine. The urge to use cocaine was assessed with a ques
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e1b577ba40c6f054e1408a9e124d307
https://doi.org/10.1007/bf00443414
https://doi.org/10.1007/bf00443414
Autor:
Jerome H. Jaffe, Ron Herning, Craig T. Nagoshi, Karen M. Kumor, Nicola G. Cascella, Carles Muntaner
Publikováno v:
Psychopharmacology. 99:282-286
Subjective and physiological responses of eight male cocaine-using research volunteers were studied after a double-blind saline infusion (placebo) was given when subjects were instructed that a cocaine infusion might be given. Cardiovascular and subj
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43819a131e83b766f7589c0d3a22dfb7
https://doi.org/10.1007/bf00442823
https://doi.org/10.1007/bf00442823
Publikováno v:
Journal of Analytical Toxicology. 11:36-38
The presence of cocaine was confirmed in the saliva of two male human subjects who had received intravenous doses of cocaine. For one subject, the saliva:plasma concentration ratios varied from 2.96 to 0.5 over time following drug administration. Cor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::51608e5e70a81ef5c562d3d2348853f8
https://doi.org/10.1093/jat/11.1.36
https://doi.org/10.1093/jat/11.1.36