Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Karen M. Kopydlowski"'
Autor:
Afif Ben Salah, Amor Zaâtour, Nathalie Ben Messaoud, Abdelhamid Kidar, Philip L Smith, Karen M Kopydlowski, Mara Kreishman-Deitrick, Carl J Nielsen, Anne Novitt-Moreno, Janet H Ransom, Gloria Morizot, Max Grogl, Pierre A Buffet
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 8, Iss 5, p e2749 (2014)
Externí odkaz:
https://doaj.org/article/d5f13977b69541b5b4662639efcf4075
Autor:
Carmenza Spadafora, Gordon A Awandare, Karen M Kopydlowski, Jozsef Czege, J Kathleen Moch, Robert W Finberg, George C Tsokos, José A Stoute
Publikováno v:
PLoS Pathogens, Vol 6, Iss 6, p e1000968 (2010)
Plasmodium falciparum is a highly lethal malaria parasite of humans. A major portion of its life cycle is dedicated to invading and multiplying inside erythrocytes. The molecular mechanisms of erythrocyte invasion are incompletely understood. P. falc
Externí odkaz:
https://doaj.org/article/93b10422577b498c9c5fe9579b2cfaed
Autor:
José E. Calzada, William F. McCarthy, Melissa Nieto, Nestor Sosa, Mara Kreishman-Deitrick, Max Grogl, Zeuz Capitán, Charles Scott, Judith Berman, Karen M. Kopydlowski, Janet Ransom, Javier Nieto, Hector Paz, Carmenza Spadafora, Diane Ullman
Publikováno v:
The American Journal of Tropical Medicine and Hygiene
In this randomized, double-blinded Phase 2 trial, 30 patients with Leishmania panamensis cutaneous leishmaniasis were randomly allocated (1:1) to receive once daily topical treatment with WR 279,396 (15% paromomycin + 0.5% gentamicin) or Paromomycin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db6bb6b5e9d7b2154122175a40bb78e6
https://doi.org/10.4269/ajtmh.12-0736
https://doi.org/10.4269/ajtmh.12-0736
Autor:
Sergio A. Lira, Karen Thomas, M. Joshua Cody, Stefanie N. Vogel, Masayuki Fukata, Louis J. DeTolla, Karen M. Kopydlowski, Aiping Zhao, Terez Shea-Donohue
Publikováno v:
Innate Immunity. 14:117-124
The role of TLRs and MyD88 in the maintenance of gut integrity in response to dextran sodium sulfate (DSS)-induced colitis was demonstrated recently and led to the conclusion that the innate immune response to luminal commensal flora provides necessa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba2350b98279e86f8d0c6fde5af844e0
https://doi.org/10.1177/1753425908088724
https://doi.org/10.1177/1753425908088724
Publikováno v:
The Journal of Immunology. 164:5564-5574
In this study, the effect of in vitro endotoxin tolerance on LPS-induced mitogen-activated protein kinase activation, transcription factor induction, and cytokine, chemokine, and Toll-like receptor (TLR) 2 and 4 gene expression, as well as the involv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d7feb8bcb839679182e0d7ed1b639923
https://doi.org/10.4049/jimmunol.164.11.5564
https://doi.org/10.4049/jimmunol.164.11.5564
Autor:
Yuh-Jing Lin, Nestor Sosa, William R. Ravis, Alejandro Llanos-Cuentas, Carl J. Nielsen, Philip L. Smith, Kirsten S. Smith, Karen M. Kopydlowski, Mara Kreishman-Deitrick, Janet Ransom, Max Grogl
Publikováno v:
Antimicrobial agents and chemotherapy. 57(10)
This study evaluated the pharmacokinetics of topical creams containing 15% paromomycin (“paromomycin alone”) and 15% paromomycin plus 0.5% gentamicin (WR 279,396) in patients with cutaneous leishmaniasis. The investigational creams were applied t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d5867ffdffae31503acd9936968e8b63
https://pubmed.ncbi.nlm.nih.gov/23877689
https://pubmed.ncbi.nlm.nih.gov/23877689
Autor:
Diane Ullman, Aicha Boukthir, Nabil Belhadj Hamida, Ryan C. Adams, Kirsten S. Smith, Mourad Mokni, Jihene Bettaieb, Zaher El Ahmadi, Philip L. Smith, Adel Gharbi, Robert M. Rice, George D. Thorne, Nissaf Ben Alaya, A. Zaatour, Carl J. Nielsen, Jeanne A. Norwood, Max Grogl, Hechmi Louzir, Sadok Chlif, Gloria Morizot, William F. McCarthy, Alan J. Magill, Afif Ben Salah, Mara Kreishman-Deitrick, Karen M. Kopydlowski, Janet Ransom, Judith Berman, Pierre Buffet, Nathalie Ben Messaoud, Kidar Abdelhamid, Evelyn Guedri, Douglas B. Tang
Publikováno v:
New England Journal of Medicine
New England Journal of Medicine, Massachusetts Medical Society, 2013, 368 (6), pp.524-32. ⟨10.1056/NEJMoa1202657⟩
New England Journal of Medicine, 2013, 368 (6), pp.524-32. ⟨10.1056/NEJMoa1202657⟩
New England Journal of Medicine, Massachusetts Medical Society, 2013, 368 (6), pp.524-32. ⟨10.1056/NEJMoa1202657⟩
New England Journal of Medicine, 2013, 368 (6), pp.524-32. ⟨10.1056/NEJMoa1202657⟩
International audience; BACKGROUND: There is a need for a simple and efficacious treatment for cutaneous leishmaniasis with an acceptable side-effect profile. METHODS: We conducted a randomized, vehicle-controlled phase 3 trial of topical treatments
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7048bbfb40ab6d667daf8f05bd432e4
https://hal-riip.archives-ouvertes.fr/pasteur-00793585/file/Topical_Paromomycin_with_or_without_Gentamicin_for_Cutaneous_Leishmaniasis.pdf
https://hal-riip.archives-ouvertes.fr/pasteur-00793585/file/Topical_Paromomycin_with_or_without_Gentamicin_for_Cutaneous_Leishmaniasis.pdf
Publikováno v:
Malaria Journal
Malaria Journal, Vol 10, Iss 1, p 96 (2011)
Malaria Journal, Vol 10, Iss 1, p 96 (2011)
Background Percoll gradient centrifugation is often used for synchronization, enrichment, or isolation of a particular stage of Plasmodium falciparum. However, Percoll, a hyperosmotic agent, may have harmful effects on the parasites. Magnetic bead co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a62e420b06ad6de319d5cbc2ce64dbb
https://pubmed.ncbi.nlm.nih.gov/21501476
https://pubmed.ncbi.nlm.nih.gov/21501476
Autor:
José A. Stoute, Karen M. Kopydlowski, Gordon A. Awandare, J. Kathleen Moch, Carmenza Spadafora, Robert W. Finberg, George C. Tsokos, Jozsef Czege
Publikováno v:
PLoS Pathogens, Vol 6, Iss 6, p e1000968 (2010)
PLoS Pathogens
PLoS Pathogens
Plasmodium falciparum is a highly lethal malaria parasite of humans. A major portion of its life cycle is dedicated to invading and multiplying inside erythrocytes. The molecular mechanisms of erythrocyte invasion are incompletely understood. P. falc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b298cb1941f8d3347f0d4b62003d46f
http://europepmc.org/articles/PMC2887475?pdf=render
http://europepmc.org/articles/PMC2887475?pdf=render
Autor:
Zhiyu Li, Patrice Sellers, Sean T. Prigge, Jill T Ferlan, Malcolm J. Gardner, Shamira J. Shallom, Norman C. Waters, Cassandra L. Woodard, Lan Wei, Karen M. Kopydlowski, Patricia J. Lee, Tadeusz Guszczynski
Publikováno v:
Molecular and biochemical parasitology. 123(2)
The genome of the malaria parasite, Plasmodium falciparum, appears to contain the proteins necessary for a Type II dissociated fatty acid biosynthetic system. Here we report the functional characterization of two proteins from this system. Purified r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c25d6107d6ed4c8646724804116e032
https://pubmed.ncbi.nlm.nih.gov/12270624
https://pubmed.ncbi.nlm.nih.gov/12270624