Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Karen M. Kennedy-Wilson"'
Autor:
Anastasia Wyce, Gopinath Ganji, Kimberly N Smitheman, Chun-Wa Chung, Susan Korenchuk, Yuchen Bai, Olena Barbash, BaoChau Le, Peter D Craggs, Michael T McCabe, Karen M Kennedy-Wilson, Lydia V Sanchez, Romain L Gosmini, Nigel Parr, Charles F McHugh, Dashyant Dhanak, Rab K Prinjha, Kurt R Auger, Peter J Tummino
Publikováno v:
PLoS ONE, Vol 8, Iss 8, p e72967 (2013)
BET family proteins are epigenetic regulators known to control expression of genes involved in cell growth and oncogenesis. Selective inhibitors of BET proteins exhibit potent anti-proliferative activity in a number of hematologic cancer models, in p
Externí odkaz:
https://doaj.org/article/edc29a7e49b54f8688b20ca3340035d5
Autor:
Gustavo Arruda Bezerra, Elena Dobrovetsky, Aiping Dong, Almagul Seitova, Lissete Crombett, Lisa M Shewchuk, Annie M Hassell, Sharon M Sweitzer, Thomas D Sweitzer, Patrick J McDevitt, Kyung O Johanson, Karen M Kennedy-Wilson, Doug Cossar, Alexey Bochkarev, Karl Gruber, Sirano Dhe-Paganon
Publikováno v:
PLoS ONE, Vol 7, Iss 8, p e43019 (2012)
Proline-specific dipeptidyl peptidases (DPPs) are emerging targets for drug development. DPP4 inhibitors are approved in many countries, and other dipeptidyl peptidases are often referred to as DPP4 activity- and/or structure-homologues (DASH). Membe
Externí odkaz:
https://doaj.org/article/9376f8c95b9b47d38a60f33aab898172
A coding polymorphism in the CYSLT2 receptor with reduced affinity to LTD4 is associated with asthma
Autor:
Mathias Chiano, Michael J. Wagner, Henry M. Sarau, Wayne H. Anderson, Mary E. Fling, Louise Hosking, Peter T. Buckley, Catherine S. Sprankle, Karen M. Kennedy-Wilson, Andrew Green, Dulcie B. Schmidt, William E. Wixted, Ashley A. Barnes, Lee-Ann Cameron, Diane M. Ignar, Sreekumar G. Pillai, Diane Joan Cousens, Jørgen Vestbo, James J. Foley, Malcolm N. Blumenthal
Publikováno v:
Pharmacogenetics. 14:627-633
Cysteinyl leukotrienes (CYSLTR) are potent biological mediators in the pathophysiology of asthma for which two receptors have been characterized, CYSLTR1 and CYSLTR2. The leukotriene modifying agents currently used to control bronchoconstriction and
Autor:
Dashyant Dhanak, Romain Luc Marie Gosmini, Olena Barbash, Rab K. Prinjha, BaoChau Le, Gopinath Ganji, Kimberly N. Smitheman, Chun-wa Chung, Karen M. Kennedy-Wilson, Nigel J. Parr, Peter D. Craggs, Charles F. McHugh, Lydia V. Sanchez, Peter J. Tummino, Yuchen Bai, Anastasia Wyce, Susan Korenchuk, Kurt R. Auger, Michael T. McCabe
Publikováno v:
PLoS ONE, Vol 8, Iss 8, p e72967 (2013)
PLoS ONE
PLoS ONE
BET family proteins are epigenetic regulators known to control expression of genes involved in cell growth and oncogenesis. Selective inhibitors of BET proteins exhibit potent anti-proliferative activity in a number of hematologic cancer models, in p
Autor:
Annie M. Hassell, Lisa M. Shewchuk, Patrick McDevitt, Elena Dobrovetsky, Lissete Crombett, Thomas D. Sweitzer, Doug Cossar, Aiping Dong, Karen M. Kennedy-Wilson, Sirano Dhe-Paganon, Almagul Seitova, Alexey Bochkarev, Sharon Sweitzer, Karl Gruber, Gustavo Arruda Bezerra, Kyung O. Johanson
Publikováno v:
PLoS ONE
PLoS ONE, Vol 7, Iss 8, p e43019 (2012)
PLoS ONE, Vol 7, Iss 8, p e43019 (2012)
Proline-specific dipeptidyl peptidases (DPPs) are emerging targets for drug development. DPP4 inhibitors are approved in many countries, and other dipeptidyl peptidases are often referred to as DPP4 activity- and/or structure-homologues (DASH). Membe
Autor:
Andrew D. Rhodes, Phil Hardwicke, Sharon Sweitzer, Sundip Modha, Huizhen J. Zhao, Karen M. Kennedy-Wilson, Steve L. Martin, Martin J. Scott, Neil Broadway
Publikováno v:
Protein expression and purification. 52(1)
Baculovirus vectors engineered to contain mammalian cell-active promoter elements have been described as an efficient method for transduction of a broad spectrum of human cell lines at high frequency. In the first large-scale comparative study of sec