Zobrazeno 1 - 10
of 53
pro vyhledávání: '"Karen M. Bussard"'
Publikováno v:
Breast Cancer Research, Vol 21, Iss 1, Pp 1-30 (2019)
Abstract Introduction In a cancer-free environment in the adult, the skeleton continuously undergoes remodeling. Bone-resorbing osteoclasts excavate erosion cavities, and bone-depositing osteoblasts synthesize osteoid matrix that forms new bone, with
Externí odkaz:
https://doaj.org/article/bd65e56acfd14d24beac4740baf0a992
Autor:
Karen M. Bussard, Gilbert H. Smith
Publikováno v:
International Journal of Cell Biology, Vol 2011 (2011)
The mammary gland is a unique organ that continually undergoes postnatal developmental changes. In mice, the mammary gland is formed via signals from terminal end buds, which direct ductal growth and elongation. Intriguingly, it is likely that the en
Externí odkaz:
https://doaj.org/article/fe0f0b83f47940b8b16d223273d6a5f8
Autor:
Karen M. Bussard, Jonathan R. Brody, Gang Ning, Lebaron C. Agostini, Manish Neupane, Alison B. Shupp
Supplemental Table 1. Antibodies used for immunofluorescence Supplemental Table 2. Antibodies used for western blotting Supplemental Figure 1: EO-MCF7 sEVs decrease MCF7 proliferation. Supplemental Figure 2: Primary EO sEVs regulate MDA-MB-231 S-phas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63cd35ba7596b9517388dda9c1c10ffc
https://doi.org/10.1158/1541-7786.22527006
https://doi.org/10.1158/1541-7786.22527006
Autor:
Jonathan R. Brody, Charles J. Yeo, Karen M. Bussard, Grace McCarthy, Avinoam Nevler, Alison Shupp, Aditi Jain, Lebaron C. Agostini
Figure S3 shows IHC staining and quantification of Ki67 and phospho-h2ax
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d0a2c19185bdfebb95e3bdee6adbdb3
https://doi.org/10.1158/1541-7786.22526366
https://doi.org/10.1158/1541-7786.22526366
Autor:
Jonathan R. Brody, Charles J. Yeo, Karen M. Bussard, Grace McCarthy, Avinoam Nevler, Alison Shupp, Aditi Jain, Lebaron C. Agostini
The DNA damage response (DDR) pathway sets the stage for tumorigenesis and provides both an opportunity for drug efficacy and resistance. Therapeutic approaches to target the DDR pathway include aiming to increase the efficacy of cytotoxic chemothera
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bfbb755a0b43ace0d442549e53ecf603
https://doi.org/10.1158/1541-7786.c.6545066.v1
https://doi.org/10.1158/1541-7786.c.6545066.v1
Autor:
Karen M. Bussard, Jonathan R. Brody, Gang Ning, Lebaron C. Agostini, Manish Neupane, Alison B. Shupp
Bone is a common site of cancer metastasis, including cancers such as breast, prostate, and multiple myeloma. Disseminated tumor cells (DTC) shed from a primary tumor may travel to bone and can survive undetected for years before proliferating to for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::11457c1781993ac518c4e8aaef1bfa26
https://doi.org/10.1158/1541-7786.c.6545289.v1
https://doi.org/10.1158/1541-7786.c.6545289.v1
Supplementary Figures 1-3, Tables 1-2 from Reprogramming Human Cancer Cells in the Mouse Mammary Gland
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ad5604dff36985fa3d1112e482b3161
https://doi.org/10.1158/0008-5472.22383426
https://doi.org/10.1158/0008-5472.22383426
The tissue microenvironment directs stem/progenitor cell behavior. Cancer cells are also influenced by the microenvironment. It has been shown that, when placed into blastocysts, cancer cells respond to embryonic cues and differentiate according to t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::357c47db70dec9db052e5949710fc16d
https://doi.org/10.1158/0008-5472.c.6500535
https://doi.org/10.1158/0008-5472.c.6500535
Autor:
Avinoam Nevler, Aditi Jain, Jonathan R. Brody, Alison B. Shupp, Karen M. Bussard, Charles J. Yeo, Lebaron C. Agostini, Grace A. McCarthy
Publikováno v:
Mol Cancer Res
The DNA damage response (DDR) pathway sets the stage for tumorigenesis and provides both an opportunity for drug efficacy and resistance. Therapeutic approaches to target the DDR pathway include aiming to increase the efficacy of cytotoxic chemothera
Publikováno v:
Curr Osteoporos Rep
PURPOSE OF REVIEW: In this review, we describe the biology of extracellular vesicles (EV) and how they contribute to bone-associated cancers. RECENT FINDINGS: Crosstalk between tumor and bone have been demonstrated to promote tumor and metastatic pro