Regulation of β2-adrenoceptors in brain glia: implications for neuroinflammatory and degenerative disorders

Autor: Karen M Ryan, Andrew Harkin

Publikováno v: Neural Regeneration Research, Vol 15, Iss 11, Pp 2035-2036 (2020)

Externí odkaz: https://doaj.org/article/2ae5294361644b5b92918594246728b7

Blood plasma B vitamins in depression and the therapeutic response to electroconvulsive therapy

Autor: Karen M. Ryan, Kelly A. Allers, Andrew Harkin, Declan M. McLoughlin

Publikováno v: Brain, Behavior, & Immunity - Health, Vol 4, Iss , Pp 100063- (2020)

A growing body of research has indicated a role for B vitamins in depression, with some previous studies suggesting that B vitamin status in patients with depression can impact on antidepressant response. Here we aimed to investigate B vitamin plasma

Externí odkaz: https://doaj.org/article/f5b1eaceeb474ef3a2990429f8b80a68

PARP1 and OGG1 in medicated patients with depression and the response to ECT

Autor: Karen M Ryan, Declan M McLoughlin

Publikováno v: The international journal of neuropsychopharmacology.

Background Oxidative stress and oxidation-induced DNA damage may contribute to the pathophysiology of depression. Two key mediators of base excision repair (BER) in response to oxidative damage of DNA are OGG1 and PARP1. Few studies have examined cha

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b94c694f813b6b5a306fd1a59b159d5
https://pubmed.ncbi.nlm.nih.gov/36472850

Interrogating Associations Between Polygenic Liabilities and Electroconvulsive Therapy Effectiveness

Autor: Gunter Kenis, Edwin van Dellen, Martijn Arns, Tom K. Birkenhäger, Esmée Verwijk, Bochao Lin, Iris E. C. Sommer, Metten Somers, Linda van Diermen, Bart P. F. Rutten, Dore Loef, Karen M. Ryan, Suzanne C. van Bronswijk, Bernhard T. Baune, Declan M. McLoughlin, Jasper O. Nuninga, Eric van Exel, Mardien L. Oudega, Marco P. Boks, Jurjen J. Luykx, D Rhebergen, Baer Arts, Philip van Eijndhoven, Geert Schurgers, Annemiek Dols, Didier Schrijvers, Sinan Guloksuz, Sigfried Schouws

Publikováno v: Biological Psychiatry, 91(6), 531-539. Elsevier USA
Biological Psychiatry, 91(9), S55-S55. Elsevier Science
Luykx, J J, Loef, D, Lin, B, van Diermen, L, Nuninga, J O, van Exel, E, Oudega, M L, Rhebergen, D, Schouws, S N T M, van Eijndhoven, P, Verwijk, E, Schrijvers, D, Birkenhager, T K, Ryan, K M, Arts, B, van Bronswijk, S C, Kenis, G, Schurgers, G, Baune, B T, Arns, M, van Dellen, E E, Somers, M, Sommer, I E C, Boks, M P, Gülöksüz, S, McLoughlin, D M, Dols, A & Rutten, B P F 2022, ' Interrogating Associations Between Polygenic Liabilities and Electroconvulsive Therapy Effectiveness ', Biological Psychiatry, vol. 91, no. 6, pp. 531-539 . https://doi.org/10.1016/j.biopsych.2021.10.013
Biological Psychiatry, 91, 6, pp. 531-539
Biological Psychiatry, 91(6), 531-539. Elsevier Inc.
Biological psychiatry
Biological Psychiatry, 91(6), 531-539. Elsevier Science
Biological psychiatry. Elsevier USA
Maastricht University
Biological Psychiatry, 91, 531-539
Biological Psychiatry, 91(6), 531-539. ELSEVIER SCIENCE INC
Biological Psychiatry, 91(6), 531-539. Elsevier

Background: Electroconvulsive therapy (ECT) is the most effective treatment for severe major depressive episodes (MDEs). Nonetheless, firmly established associations between ECT outcomes and biological variables are currently lacking. Polygenic risk

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12dad662e4aff1b3a838fc55b82fb838
https://pubmed.ncbi.nlm.nih.gov/34955169

Peripheral blood E2F1 mRNA in depression and following electroconvulsive therapy

Autor: Karen M. Ryan, Erik Kolshus, Declan M. McLoughlin, Claire L. McGrory

Publikováno v: Progress in Neuro-Psychopharmacology and Biological Psychiatry. 89:380-385

The E2F transcription factors are a group of proteins that bind to the promotor region of the adenovirus E2 gene. E2F1, the first family member to be cloned, is linked to functions including cell proliferation and apoptosis, DNA repair, cell senescen

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e22d61c1982eeb26f7566117b5064f2
https://doi.org/10.1016/j.pnpbp.2018.10.011