Zobrazeno 1 - 10
of 192
pro vyhledávání: '"Karen M Lyons"'
Publikováno v:
PLoS Genetics, Vol 12, Iss 10, p e1006352 (2016)
TGFβs act through canonical and non-canonical pathways, and canonical signals are transduced via Smad2 and Smad3. However, the contribution of canonical vs. non-canonical pathways in cartilage is unknown because the role of Smad2 in chondrogenesis h
Externí odkaz:
https://doaj.org/article/bdeab3825787456cb29d7db0f9e072b5
Autor:
Jennifer Zieba, Kimberly Nicole Forlenza, Jagteshwar Singh Khatra, Anna Sarukhanov, Ivan Duran, Diana Rigueur, Karen M Lyons, Daniel H Cohn, Amy E Merrill, Deborah Krakow
Publikováno v:
PLoS Genetics, Vol 12, Iss 3, p e1005936 (2016)
Spondylocarpotarsal synostosis (SCT) is an autosomal recessive disorder characterized by progressive vertebral fusions and caused by loss of function mutations in Filamin B (FLNB). FLNB acts as a signaling scaffold by linking the actin cytoskleteon t
Externí odkaz:
https://doaj.org/article/da40369062c3426fb7af100e7c21aaf7
Autor:
Faith Hall-Glenn, R Andrea De Young, Bau-Lin Huang, Ben van Handel, Jennifer J Hofmann, Tom T Chen, Aaron Choi, Jessica R Ong, Paul D Benya, Hanna Mikkola, M Luisa Iruela-Arispe, Karen M Lyons
Publikováno v:
PLoS ONE, Vol 7, Iss 2, p e30562 (2012)
CCN2/Connective Tissue Growth Factor (CTGF) is a matricellular protein that regulates cell adhesion, migration, and survival. CCN2 is best known for its ability to promote fibrosis by mediating the ability of transforming growth factor β (TGFβ) to
Externí odkaz:
https://doaj.org/article/c9188197a81f442bb161d3ab4a6bcd26
Autor:
Brendan Y. Shi, Varun Sriram, Shannon Y. Wu, Dave Huang, Alexis Cheney, Melodie F. Metzger, Oskar Sundberg, Karen M. Lyons, Charles E. McKenna, Ichiro Nishimura, Thomas J. Kremen
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 12 (2024)
Background: Osteoadsorptive fluorogenic sentinel 3 (OFS-3) is a recently described compound that contains a bone-targeting bisphosphonate (BP) and cathepsin K (Ctsk)-triggered fluorescence signal. A prior study in a murine Achilles repair model demon
Externí odkaz:
https://doaj.org/article/a4ab903c667d429f834a03dd11eeb2a1
Autor:
Thomas J. Kremen, Brendan Y. Shi, Shannon Y. Wu, Oskar Sundberg, Varun Sriram, Won Kim, Dmitriy Sheyn, Karen M. Lyons, Weiguang Wang, Charles E. McKenna, Ichiro Nishimura
Publikováno v:
Journal of Orthopaedic Research.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::83b9233429bb4d6c704c64ecddda2495
https://doi.org/10.1002/jor.25579
https://doi.org/10.1002/jor.25579
Autor:
Viktoria Xega, Mahvash Zakikhani, Noah Lopez, Marzieh Eskandari Shahraki, Karen M Lyons, Jun-Li Liu
Publikováno v:
Journal of the Endocrine Society. 6:A360-A361
CCN5/WISP2 is a matricellular protein, the expression of which is under the regulation of Wnt signaling and IGF-1. Our initial characterization supports the notion that CCN5 promotes the proliferation and survival of pancreatic β-cells leading to me
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::58612883fd0234aa458f4f9e7b97b778
https://doi.org/10.1210/jendso/bvac150.749
https://doi.org/10.1210/jendso/bvac150.749
Autor:
Yucheng Lin, Jinxiu Lu, Frank A. Petrigliano, Ruzanna Shkhyan, Nancy Q. Liu, Noah Lopez, Zorica Buser, Denis Evseenko, Jiankang Zhang, Arijita Sarkar, Liming Wang, Liangliang Li, Jade Tassey, Dawei Geng, Tea Jashashvili, Jenny Magallanes, Ben Van Handel, Karen M. Lyons
Growth of long bones and vertebrae is maintained postnatally by a long-lasting pool of progenitor cells. Little is known about the molecular mechanisms that regulate the output and maintenance of the cells that give rise to mature cartilage. Here we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::827e4e8440f09ae4d85ef5c4c3c3dae0
https://doi.org/10.1101/2021.10.12.464120
https://doi.org/10.1101/2021.10.12.464120
Autor:
Justin Ross, Ghiath Alnouri, Dylan Vance, Robert T. Sataloff, Ashley P. O'Connell Ferster, Karissa Russell, Asyia Ahmad, Karen M. Lyons, Jin Park, Ralph R Turner, Srihari Daggumati, Wei Wu
Publikováno v:
Journal of Voice.
The purpose of this study was to compare the diagnostic utility of pH monitoring using 24-hour esophageal pH-Impedance (HEMII-pH) testing versus pharyngeal pH (Restech) testing (Respiratory Technology Corporation, Houston, Texas) for diagnosing laryn
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9424c15f87bf53f0b9e5d89191254409
https://doi.org/10.1016/j.jvoice.2021.04.002
https://doi.org/10.1016/j.jvoice.2021.04.002
Autor:
Laurence C. Cheung, Deborah H. Strickland, Meegan Howlett, Jette Ford, Adrian K. Charles, Karen M. Lyons, David R. Brigstock, Roel Goldschmeding, Catherine H. Cole, Warren S. Alexander, Ursula R. Kees
Publikováno v:
Haematologica, Vol 99, Iss 7 (2014)
Hematopoiesis occurs in a complex bone marrow microenvironment in which bone marrow stromal cells provide critical support to the process through direct cell contact and indirectly through the secretion of cytokines and growth factors. We report that
Externí odkaz:
https://doaj.org/article/69074d34281e41a8860bb989935e774c
Determining normal values for lower trachea and bronchi size in children by computed tomography (CT)
Autor:
Stewart Bruce Greenberg, Nayanatara Swamy, Uday Kumar Chalwadi, Amit Agarwal, Karen M. Lyons, Clinton Heath Gauss
Publikováno v:
Pediatric pulmonologyREFERENCES. 56(9)
Background Normative data for central airway dimensions are a prerequisite to objectively assess large airway pathologies. Studies with computed tomography (CT) measurements of normal trachea and bronchi size in children are scarce. Objective The pur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e1980891e1a484d127d8244d81218643
https://pubmed.ncbi.nlm.nih.gov/34133085
https://pubmed.ncbi.nlm.nih.gov/34133085