Zobrazeno 1 - 10
of 220
pro vyhledávání: '"Karen M Henkels"'
Publikováno v:
PLoS ONE, Vol 11, Iss 11, p e0166553 (2016)
Phospholipase D-2 (PLD2) has a key role in breast cancer formation and metastasis formation with PLD small inhibitors reducing primary tumor growth. This study aimed to evaluate the importance of targeting PLD on the tumor microenvironment. We provid
Externí odkaz:
https://doaj.org/article/b8c4742784584fe48c8640ff35447bdd
Publikováno v:
Frontiers in Molecular Biosciences, Vol 8 (2021)
Ras proteins are membrane-bound small GTPases that promote cell proliferation, differentiation, and apoptosis. Consistent with this key regulatory role, activating mutations of Ras are present in ∼19% of new cancer cases in the United States per ye
Externí odkaz:
https://doaj.org/article/bcdbbb8babb14afd849d9081a3a4bf54
Autor:
Ericson John V. Torralba, Shikshita Singh, Robert F. Short, Christine M. Rapp, Karen M. Henkels, Ravi P. Sahu, Jeffrey B. Travers
Publikováno v:
Skin Research and Technology. 29
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e22b283a09a93fe6726eeb2be7d7c24d
https://doi.org/10.1111/srt.13332
https://doi.org/10.1111/srt.13332
Autor:
Hong Liang, Kristen M. Rehl, Yong Zhou, Karen M. Henkels, Jordan U. Gutterman, Christian M. Garrido, Kwang-Jin Cho
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-18 (2020)
Scientific Reports
Scientific Reports
K-Ras must interact primarily with the plasma membrane (PM) for its biological activity. Therefore, disrupting K-Ras PM interaction is a tractable approach to block oncogenic K-Ras activity. Here, we found that avicin G, a family of natural plant-der
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fda751f8a01b9601fda15878fc696495
http://link.springer.com/article/10.1038/s41598-020-65882-5
http://link.springer.com/article/10.1038/s41598-020-65882-5
Autor:
Charles N. Serhan, Nagarjuna R. Cheemarla, Xavier de la Rosa, Julian Gomez-Cambronero, Ramya Ganesan, Krushangi N. Shah, Karen M. Henkels, Stephania Libreros
Publikováno v:
FASEB J
A successful acute inflammatory response results in the elimination of infectious agents by neutrophils and monocytes, followed by resolution and repair through tissue-resident and recruited macrophages. Resolvins (D-series and E-series) are pro-reso
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b2630a229f5b415e70687282d7bf9fa3
https://pubmed.ncbi.nlm.nih.gov/33047359
https://pubmed.ncbi.nlm.nih.gov/33047359
Autor:
Ramya Ganesan, Julian Gomez-Cambronero, Karen M. Henkels, Michael A. Frohman, Yasunori Kanaho, Lucile E. Wrenshall, Gilbert Di Paolo
Publikováno v:
Journal of Leukocyte Biology. 103:867-883
The uptake of cholesterol carried by low-density lipoprotein (LDL) is tightly controlled in the body. Macrophages are not well suited to counteract the cellular consequences of excess cholesterol leading to their transformation into “foam cells,”
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce6a2056228a7cb78fcc5b747ea0c176
https://doi.org/10.1002/jlb.2a1017-407rr
https://doi.org/10.1002/jlb.2a1017-407rr
Autor:
Charles N. Serhan, Krushangi N. Shah, Ramya Ganesan, Karen M. Henkels, Julian Gomez-Cambronero, Nagarjuna R. Cheemarla, Xavier de la Rosa, Stephania Libreros
A successful acute inflammatory response results in the elimination of infectious agents by neutrophils and monocytes, followed by resolution and repair by tissue-resident and recruited macrophages. D-series resolvins are pro-resolving mediators invo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ec60b9976c1d429b85107c0715cff60
Autor:
Karen M. Henkels, Ramya Ganesan, Julian Gomez-Cambronero, Taylor E. Miller, Kristen Fite, Brandon A. Wilkins
Publikováno v:
Oncotarget
// Karen M. Henkels 2 , Taylor E. Miller 2 , Ramya Ganesan 2 , Brandon A. Wilkins 2 , Kristen Fite 2 and Julian Gomez-Cambronero 1,2 1 Center for Experimental Therapeutics and Reperfusion Injury, Brigham and Women Hospital and Harvard Medical School,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52afa211bfaf3df83a5bc34aaf27e2fc
https://doi.org/10.18632/oncotarget.9685
https://doi.org/10.18632/oncotarget.9685
Autor:
Rebecca M. Baron, Taylor E. Miller, David N. Douda, Julian Gomez-Cambronero, Alexander H. Tavares, Bruce D. Levy, Judie A. Howrylak, Raja-Elie E. Abdulnour, Karen M. Henkels, Laura E. Fredenburgh
Publikováno v:
Journal of leukocyte biology. 103(5)
Phospholipase D (PLD) plays important roles in cellular responses to tissue injury that are critical to acute inflammatory diseases, such as the acute respiratory distress syndrome (ARDS). We investigated the expression of PLD isoforms and related ph
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9fb6989d5ba9a15dbca2b8c7bf01b3e9
https://pubmed.ncbi.nlm.nih.gov/29437245
https://pubmed.ncbi.nlm.nih.gov/29437245