Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Karen M Doody"'
Autor:
Syed-Wajahat Hassan, Karen M Doody, Serge Hardy, Noriko Uetani, Denis Cournoyer, Michel L Tremblay
Publikováno v:
PLoS ONE, Vol 5, Iss 1, p e8868 (2010)
T cell protein tyrosine phosphatase (TC-PTP/PTPN2) is an enzyme that is essential for the proper functioning of the immune system and that participates in the control of cell proliferation, and inflammation. We previously observed that TC-PTP(-/-) mi
Externí odkaz:
https://doaj.org/article/df69c264e6f24e7da18d7cfc14b32b6a
Autor:
Tiffany A. Fillier, Shrushti Shah, Karen M. Doody, Thu H. Pham, Isabelle Aubry, Michel L. Tremblay, Sukhinder K. Cheema, Jacqueline Blundell, Raymond H. Thomas
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-16 (2022)
Abstract Communication between gut microbiota and the brain is an enigma. Alterations in the gut microbial community affects enteric metabolite levels, such as short chain fatty acids (SCFAs). SCFAs have been proposed as a possible mechanism through
Externí odkaz:
https://doaj.org/article/b5d54eeb0b314ea2988f7514b326c0e7
Autor:
Muhammad Nadeem, Evan Wheeler, Melissa C. Hamilton, Raymond Thomas, Natalia P. Vidal, Thu Huong Pham, Karen M. Doody, Charles F. Manful
Publikováno v:
MethodsX, Vol 6, Iss, Pp 2686-2697 (2019)
MethodsX
MethodsX
Graphical abstract
Cooking techniques such as grilling confer several benefits to meat during food preparation including improved palatability, digestibility, preservation, and safety, as well as enhancing the sensory characteristics and net nut
Cooking techniques such as grilling confer several benefits to meat during food preparation including improved palatability, digestibility, preservation, and safety, as well as enhancing the sensory characteristics and net nut
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8765e04203c140b7073dc943e4424571
https://doi.org/10.1016/j.mex.2019.11.014
https://doi.org/10.1016/j.mex.2019.11.014
Autor:
Tiffany A, Fillier, Shrushti, Shah, Karen M, Doody, Thu H, Pham, Isabelle, Aubry, Michel L, Tremblay, Sukhinder K, Cheema, Jacqueline, Blundell, Raymond H, Thomas
Publikováno v:
Scientific reports. 12(1)
Communication between gut microbiota and the brain is an enigma. Alterations in the gut microbial community affects enteric metabolite levels, such as short chain fatty acids (SCFAs). SCFAs have been proposed as a possible mechanism through which the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::83b5352f4d39119e2d72b3244b86a86f
https://pubmed.ncbi.nlm.nih.gov/35999262
https://pubmed.ncbi.nlm.nih.gov/35999262
Autor:
Blundell J, Michel L. Tremblay, Tiffany A. Fillier, Sukhinder K. Cheema, Shah S, Thu Huong Pham, Raymond Thomas, Isabelle Aubry, Karen M. Doody
Communication between gut microbiota and the brain is an enigma. Alterations in the gut microbial community affects enteric metabolite levels, such as SCFAs. SCFAs have been proposed as a possible mechanism through which the gut microbiome modulate b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f779d3cad63fbdf419497c36ffef90bf
https://doi.org/10.1101/2021.06.01.446425
https://doi.org/10.1101/2021.06.01.446425
Autor:
Kuninobu Wakabayashi, Costantino Pitzalis, David R. Vera, Frances Humby, Martina Zoccheddu, Tsuyoshi Kasama, David L. Boyle, Gary P. Sims, Piotr Mydel, Rizi Ai, Gary S. Firestein, Shen Yang, Nunzio Bottini, Soumya Raychaudhuri, Francesco Galimi, Cristiano Sacchetti, Rebecca Hands, Anna-Karin H. Ekwall, Gyrid Nygaard, Wei Wang, Stephanie M. Stanford, Christopher V. Barback, Fumitaka Mizoguchi, Michel L. Tremblay, Kamil Slowikowski, Michael B. Brenner, Mattias Svensson, Dennis J. Wu, Christian Secchi, Eugenio Santelli, Karen M. Doody
Publikováno v:
Science Advances
eaba4353
6:eaba4353
eaba4353
6:eaba4353
PTPRS-targeted FLS-directed therapy synergizes with TNF inhibition in therapy of arthritis.
Fibroblast-like synoviocytes (FLS) are joint-lining cells that promote rheumatoid arthritis (RA) pathology. Current disease-modifying antirheumatic agent
Fibroblast-like synoviocytes (FLS) are joint-lining cells that promote rheumatoid arthritis (RA) pathology. Current disease-modifying antirheumatic agent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c766be8a0788def9ddf9944aad5b6c2e
https://ruj.uj.edu.pl/xmlui/handle/item/265835
https://ruj.uj.edu.pl/xmlui/handle/item/265835
Autor:
Natalia P. Vidal, Muhammad Nadeem, Evan Wheeler, Karen M. Doody, Charles F. Manful, Thu Huong Pham, Melissa C. Hamilton, Raymond Thomas
Publikováno v:
Data in Brief, Vol 27, Iss, Pp-(2019)
Data in Brief
Data in Brief
Objective of this data isn brief article is to present the associated data set regarding the revised article entitled “Unfiltered beer based marinades reduced exposure to carcinogens and suppressed conjugated fatty acid oxidation in grilled meats
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27de11a03731e0616c58f8aa8b0e4d1a
http://www.sciencedirect.com/science/article/pii/S2352340919311564
http://www.sciencedirect.com/science/article/pii/S2352340919311564
Autor:
Dennis J. Wu, Costantino Pitzalis, Deepa Hammaker, Yeesim Khew-Goodall, Nunzio Bottini, Michelle Le Roux, Maripat Corr, Gary S. Firestein, Cristiano Sacchetti, Angel Bottini, Beatrix Bartok, Ana Lonic, Stephanie M. Stanford, Myles Lewis, David L. Boyle, Michele Bombardieri, Karen M. Doody, Wei Wang, Rizi Ai, Martina Zoccheddu, Xiaochun Li, Vida Zhang, Tzu-Ching Meng, Lin Liu
Publikováno v:
Annals of the rheumatic diseases, vol 78, iss 5
ObjectiveWe aimed to understand the role of the tyrosine phosphatase PTPN14—which in cancer cells modulates the Hippo pathway by retaining YAP in the cytosol—in fibroblast-like synoviocytes (FLS) from patients with rheumatoid arthritis (RA).Metho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b879a37fc3299bb40290aa5975776599
https://escholarship.org/uc/item/52p5k25k
https://escholarship.org/uc/item/52p5k25k
Autor:
Tiffany A. Fillier, Charles F. Manful, Natalia P. Vidal, Karen M. Doody, Thu Huong Pham, Raymond Thomas, Ryley P. Pumphrey
Publikováno v:
Molecules
Volume 24
Issue 2
Molecules, Vol 24, Iss 2, p 232 (2019)
Volume 24
Issue 2
Molecules, Vol 24, Iss 2, p 232 (2019)
Fatty acid esters of hydroxy fatty acids (FAHFA), diglycerides (DG) and monoacetyldiglycerides (MAcDG) are gaining interest as functional lipids in pharmaceuticals and functional food formulations for managing and treating metabolic or inflammatory d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4a1b986a171567ef15eb5a241ccc205
Autor:
Cristiano Sacchetti, Ravindra Gujar, Michel L. Tremblay, Bharat Panwar, Pandurangan Vijayanand, Benjamin J Schmiedel, Gisen Kim, Mitchell Kronenberg, Grégory Seumois, Eugenio Santelli, Shen Yang, Piotr Mydel, Florian Wiede, Ferhat Ay, Tony Tiganis, Mattias Svensson, Dennis J. Wu, Shimon Sakaguchi, Isabelle Aubry, Sourya Bhattacharyya, Karen M. Doody, Nunzio Bottini, William B. Kiosses
Genetic variants at the PTPN2 locus, which encodes the tyrosine phosphatase PTPN2, cause reduced gene expression and are linked to rheumatoid arthritis (RA) and other autoimmune diseases. PTPN2 inhibits signaling through the T cell and cytokine recep
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e15a74c8b376bffee589ab1c7529c2bd
https://eprints.soton.ac.uk/428014/
https://eprints.soton.ac.uk/428014/