Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Karen M Ashe"'
Autor:
Karen M Ashe, Dinesh Bangari, Lingyun Li, Mario A Cabrera-Salazar, Scott D Bercury, Jennifer B Nietupski, Christopher G F Cooper, Johannes M F G Aerts, Edward R Lee, Diane P Copeland, Seng H Cheng, Ronald K Scheule, John Marshall
Publikováno v:
PLoS ONE, Vol 6, Iss 6, p e21758 (2011)
The neuropathic glycosphingolipidoses are a subgroup of lysosomal storage disorders for which there are no effective therapies. A potential approach is substrate reduction therapy using inhibitors of glucosylceramide synthase (GCS) to decrease the sy
Externí odkaz:
https://doaj.org/article/cd3e8f6aa28047d9b5d2eaa2ee1c6e5d
Autor:
John Marshall, Karen M Ashe, Dinesh Bangari, KerryAnne McEachern, Wei-Lien Chuang, Joshua Pacheco, Diane P Copeland, Robert J Desnick, James A Shayman, Ronald K Scheule, Seng H Cheng
Publikováno v:
PLoS ONE, Vol 5, Iss 11, p e15033 (2010)
Fabry disease is an X-linked glycosphingolipid storage disorder caused by a deficiency in the activity of the lysosomal hydrolase α-galactosidase A (α-gal). This deficiency results in accumulation of the glycosphingolipid globotriaosylceramide (GL-
Externí odkaz:
https://doaj.org/article/055bbfe4fb664b8e9074473425ff3afe
Autor:
Marian L. Fitzgibbon, Judith K. Ockene, Akilah Dulin, Kenneth S. Peterson, Joanna Buscemi, Karen M. Ashe
Publikováno v:
Translational Behavioral Medicine
We recommend training primary care clinicians in the management of obesity and overweight and referrals. Psychologists and dieticians should be included in training and adequate reimbursement provided.
Obesity is a serious chronic disease whose
Obesity is a serious chronic disease whose
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f3d120078d90ea40174f5974ab35997b
http://europepmc.org/articles/PMC7963292
http://europepmc.org/articles/PMC7963292
Autor:
Christine F. Frisard, Melissa A. Clark, Jyothi A. Pendharkar, Jamie M Faro, Judith K. Ockene, Cassie A. Eno, Karen M. Ashe, Alan C. Geller, Sybil L. Crawford, Lori Pbert
Publikováno v:
Am J Prev Med
Introduction Clinical guidelines support physician intervention consistent with the Ask, Advise, Assess, Assist, Arrange framework for adults who have obesity. However, weight management counseling curricula vary across medical schools. It is unknown
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a6a1517797492b18e2e7ecb756a0c0ac
https://europepmc.org/articles/PMC8068621/
https://europepmc.org/articles/PMC8068621/
Autor:
Kate L. Lapane, Karen M. Ashe
Publikováno v:
Journal of Women's Health. 27:651-658
Women are disproportionately affected by both obesity and food insecurity. Food insecurity occurs when there is limited ability to acquire adequate foods. It is unknown whether social support can reduce the effect of food insecurity on increased obes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de0add9c35c0773f0dc47dca08f03c28
https://doi.org/10.1089/jwh.2017.6454
https://doi.org/10.1089/jwh.2017.6454
Autor:
Sybil L. Crawford, Judith K. Ockene, Lori Pbert, Melissa A. Clark, Tom Guck, Karen M. Ashe, Monica Ann Shaw
OBJECTIVES: The United States Preventive Services Task Force (USPSTF) 2018 guideline for the management of adults with obesity continues to support screening and offering or referring patients with obesity to intensive multi-component behavioral inte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::493b810bcf637b7104e396a0836b1535
https://europepmc.org/articles/PMC6574476/
https://europepmc.org/articles/PMC6574476/
Autor:
Mukti Kulkarni, Lori Pbert, Sybil L. Crawford, Katherine M. White, Judith K. Ockene, Karen M. Ashe, Christine F. Frisard, Alan C. Geller, M. Ann Shaw, Linda C. Churchill, Catherine A. Okuliar
Publikováno v:
American journal of preventive medicine. 55(5)
Introduction Primary care providers, using brief counseling, can help patients increase motivation to initiate or maintain weight loss, improve diet, and increase physical activity. However, no prior studies have examined the degree to which primary
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b2d7d3d2c8c866f310f021648d7e0ae
https://pubmed.ncbi.nlm.nih.gov/30342638
https://pubmed.ncbi.nlm.nih.gov/30342638
Autor:
Eva Budman, Dinesh S. Bangari, Peter A. Piepenhagen, Seng H. Cheng, Karen M. Ashe, Robert J. Desnick, John P. Leonard, John Lydon, Colleen Maloney, John Marshall, Beth L. Thurberg
Publikováno v:
The American Journal of Pathology. 185:651-665
Fabry disease is an X-linked lysosomal storage disease caused by deficient activity of α-galactosidase A and the resultant systemic accumulation of globotrioasylceramide (GL-3) and related glycolipids. α-Galactosidase A gene knockout (Gla KO) mice
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fcf2dc3610fad5999226b65e80b1a290
https://doi.org/10.1016/j.ajpath.2014.11.004
https://doi.org/10.1016/j.ajpath.2014.11.004
Autor:
Sybil L. Crawford, Barbara C. Olendzki, Maria Theresa G. Basco, Monica Ann Shaw, Judith K. Ockene, Taraneh Soleymani, Katherine Margo, Diane D. Stadler, Kristi J. Ferguson, Catherine A. Okuliar, Lori Pbert, Sarita Warrier, Linda C. Churchill, Thomas P. Guck, Karen M. Ashe, Jyothi A. Pendharkar, Denise G. Jolicoeur, Rashelle B. Hayes, Alan C. Geller
Physicians have an important role addressing the obesity epidemic. Lack of adequate teaching to provide weight management counseling (WMC) is cited as a reason for limited treatment. National guidelines have not been translated into an evidence-suppo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be76840ba07c0f424419846b7ebc7430
https://europepmc.org/articles/PMC5745008/
https://europepmc.org/articles/PMC5745008/
Autor:
Karen M. Ashe, Jie Bu, Marco A. Passini, Edward H. Schuchman, John Bringas, John Marshall, John Forsayeth, James Dodge, Seng H. Cheng, Lamya S. Shihabuddin, Krystof S. Bankiewicz, Mario A. Cabrera-Salazar
Publikováno v:
Molecular therapy : the journal of the American Society of Gene Therapy, vol 20, iss 10
Niemann-Pick disease Type A (NPA) is a neuronopathic lysosomal storage disease (LSD) caused by the loss of acid sphingomyelinase (ASM). The goals of the current study are to ascertain the levels of human ASM that are efficacious in ASM knockout (ASMK
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5fbc94f7174d6e5e0cc2fccf581f584f
https://doi.org/10.1038/mt.2012.118
https://doi.org/10.1038/mt.2012.118