Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Karen Louise Mossman"'
Publikováno v:
OncoImmunology, Vol 8, Iss 6 (2019)
Oncolytic viruses (OVs) preferentially target and kill cancer cells without affecting healthy cells through a multi-modal mechanism of action. While historically the direct killing activity of OVs was considered the primary mode of action, initiation
Externí odkaz:
https://doaj.org/article/ff37b203c1a243ccad99f1b45f323134
Autor:
Chadi Zakaria, Polen Sean, Huy-Dung Hoang, Louis-Phillipe Leroux, Margaret Watson, Samuel Tekeste Workenhe, Jaclyn Hearnden, Dana Pearl, Vinh Tai Truong, Nathaniel Robichaud, Akiko Yanagiya, Soroush Tahmasebi, Seyed Mehdi Jafarnejad, Jian-Jun Jia, Adrian Pelin, Jean-Simon Diallo, Fabrice Le Boeuf, John Cameron Bell, Karen Louise Mossman, Tyson Ernst Graber, Maritza Jaramillo, Nahum Sonenberg, Tommy Alain
Publikováno v:
PLoS Pathogens, Vol 14, Iss 8, p e1007264 (2018)
Herpes Simplex Virus 1 (HSV1) is amongst the most clinically advanced oncolytic virus platforms. However, efficient and sustained viral replication within tumours is limiting. Rapamycin can stimulate HSV1 replication in cancer cells, but active-site
Externí odkaz:
https://doaj.org/article/513a554b6c4d453d9e82ff6357c01efc
Autor:
Maria Eugenia, Davola, Alyssa, Vito, Jiarun, Wei, Nader, El-Sayes, Samuel, Workenhe, Karen Louise, Mossman
Publikováno v:
Methods in enzymology. 635
Among the many immunotherapies being developed and tested both preclinically and clinically, oncolytic viruses (OVs) are gaining traction as a forerunner in the search for potent new therapeutic agents, with a genetically engineered herpes simplex vi