Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Karen Lettieri"'
Autor:
Lydia Daboussi, Giancarlo Costaguta, Miriam Gullo, Nicole Jasinski, Veronica Pessino, Brendan O’Leary, Karen Lettieri, Shawn Driscoll, Samuel L. Pfaff
Publikováno v:
Cell Reports, Vol 42, Iss 11, Pp 113282- (2023)
Summary: Schwann cells respond to acute axon damage by transiently transdifferentiating into specialized repair cells that restore sensorimotor function. However, the molecular systems controlling repair cell formation and function are not well defin
Externí odkaz:
https://doaj.org/article/6cfe1dba7eb04f18adfa9d368ab31218
Autor:
Lydia Daboussi, Giancarlo Costaguta, Miriam Gullo, Nicole Jasinski, Veronica Pessino, Brendan O’Leary, Karen Lettieri, Shawn Driscoll, Samuel L. Pfaff
SummarySchwann cells respond to acute axon damage by transiently transdifferentiating into specialized repair cells that restore sensorimotor function. However, the molecular systems controlling repair cell formation and function are not well defined
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a15da461325894e2415b1edf67a3ee77
https://doi.org/10.1101/2022.09.25.509350
https://doi.org/10.1101/2022.09.25.509350
Autor:
Dario Bonanomi, Karen Lettieri, Matthew J. Sternfeld, Miriam Gullo, Samuel L. Pfaff, Joseph W. Lewcock, Shawn P. Driscoll, Aurora Badaloni, Fabiola Valenza, Aaron Aslanian, Tony Hunter, Onanong Chivatakarn
Publikováno v:
Neuron. 102:602-620.e9
Summary The rich functional diversity of the nervous system is founded in the specific connectivity of the underlying neural circuitry. Neurons are often preprogrammed to respond to multiple axon guidance signals because they use sequential guidepost
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e42092dfe78da5d4b5daa468c691777a
https://doi.org/10.1016/j.neuron.2019.02.034
https://doi.org/10.1016/j.neuron.2019.02.034
Autor:
Karen Lettieri, Ge Bai, Dario Bonanomi, Brian A. Pierchala, Till Marquardt, Samuel L. Pfaff, Houari Abdesselem, Onanong Chivatakarn
Publikováno v:
Cell. 148:568-582
SummaryGrowing axons encounter multiple guidance cues, but it is unclear how separate signals are resolved and integrated into coherent instructions for growth cone navigation. We report that glycosylphosphatidylinositol (GPI)-anchored ephrin-As func
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d7ec4fd9c5273303ba4aae372b2678b7
https://doi.org/10.1016/j.cell.2012.01.024
https://doi.org/10.1016/j.cell.2012.01.024
Autor:
Karen Lettieri, Amy L. Firth, Helen M. Rowe, Dario Bonanomi, Wesley D. Gifford, Shawn P. Driscoll, Todd S. Macfarlan, Samuel L. Pfaff, Didier Trono, Oded Singer
Publikováno v:
Nature
Summary Embryonic stem (ES) cells are derived from blastocyst stage embryos and are believed to be functionally equivalent to the inner cell mass, which lacks the ability to produce all extraembryonic tissues. Here we report the identification of a r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::281e3ae247056f596e7e8d60ee39859f
http://europepmc.org/articles/PMC3395470
http://europepmc.org/articles/PMC3395470
Autor:
Wesley D. Gifford, Jianxun Wang, Todd S. Macfarlan, Samuel L. Pfaff, Bing Ren, Karen Lettieri, Saurabh Agarwal, Laura Franco, Shawn P. Driscoll, Michael G. Rosenfeld, Shane E. Andrews
Publikováno v:
Genes & Development. 25:594-607
Endogenous retroviruses (ERVs) constitute a substantial portion of mammalian genomes, and their retrotransposition activity helped to drive genetic variation, yet their expression is tightly regulated to prevent unchecked amplification. We generated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d53120fe10b305695aa2d8206aa79990
https://doi.org/10.1101/gad.2008511
https://doi.org/10.1101/gad.2008511
Autor:
Ge Bai, Joseph W. Lewcock, Caihong Xia, Dario Bonanomi, Karen Lettieri, Elke Stein, Onanong Chivatakarn, Laura Franco, Le Ma, Samuel L. Pfaff
Publikováno v:
Cell. 144:106-118
SummaryThe Alzheimer's disease-linked gene presenilin is required for intramembrane proteolysis of amyloid-β precursor protein, contributing to the pathogenesis of neurodegeneration that is characterized by loss of neuronal connections, but the role
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1be8cfa3388920f254483b52340a2ede
https://doi.org/10.1016/j.cell.2010.11.053
https://doi.org/10.1016/j.cell.2010.11.053
Autor:
Na Wei, Albena Jordanova, Ge Bai, Xiang-Lei Yang, Robert W. Burgess, Weiwei He, Huaqing Liu, Karen Lettieri, Yi Shi, Velina Guergueltcheva, Calin Dan Dumitru, Huihao Zhou, Samuel L. Pfaff, Janelle L. Lauer, Nicholas M. White, Veronica I. Shubayev, Patrick R. Griffin
Publikováno v:
Nature
Selective neuronal loss is a hallmark of neurodegenerative diseases, which, counterintuitively, are often caused by mutations in widely expressed genes'. Charcot-Marie-Tooth (CMT) diseases are the most common hereditary peripheral neuropathies, for w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0405df90c5e949752e9d112bca59183e
https://hdl.handle.net/10067/1294910151162165141
https://hdl.handle.net/10067/1294910151162165141
Publikováno v:
Nature. 406:515-519
Many lines of evidence indicate that genetically distinct subtypes of motor neurons are specified during development, with each type having characteristic properties of axon guidance and cell-body migration. Motor neuron subtypes express unique combi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e3b8bd733c50404757eb5d6f05c40487
https://doi.org/10.1038/35020078
https://doi.org/10.1038/35020078
Autor:
John H. Kehrl, Kathleen Harrison, Joshua P. Thaler, Karen Lettieri, Samuel L. Pfaff, Kamal Sharma
Publikováno v:
Neuron. 23:675-687
Sonic hedgehog (Shh) specifies the identity of both motor neurons (MNs) and interneurons with morphogen-like activity. Here, we present evidence that the homeodomain factor HB9 is critical for distinguishing MN and interneuron identity in the mouse.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a66e977a707eb01d36999f681a989bd4
https://doi.org/10.1016/s0896-6273(01)80027-1
https://doi.org/10.1016/s0896-6273(01)80027-1