Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Karen L. Zanotto"'
Autor:
Mirela Iodi Carstens, Margaret Ivanov, Jay Patrick Slack, Carolyn M. Sawyer, Stephan Furrer, Karen L. Zanotto, Susan Cheung, Amanda H. Klein, Earl Carstens, Christopher T. Simons
Publikováno v:
Journal of Neurophysiology. 105:1701-1710
Szechuan peppers contain hydroxy-α-sanshool that imparts desirable tingling, cooling, and numbing sensations. Hydroxy-α-sanshool activates a subset of sensory dorsal root ganglion (DRG) neurons by inhibiting two-pore potassium channels. We presentl
Publikováno v:
Neuroscience Letters. 430:29-33
Most cold-sensitive subnucleus caudalis (Vc) neurons are also excited by the TRPM8 agonist menthol and the TRPA1 agonist cinnamaldehyde (CA). We investigated how interactions among menthol, CA and noxious cooling and heating of the tongue affected re
Publikováno v:
Journal of Neurophysiology. 97:966-978
The recent discoveries of cold-sensitive transient receptor potential (TRP) channels prompted us to investigate the responses of neurons in trigeminal subnucleus caudalis (Vc) to intraoral cooling and agonists of TRPM8 and TRPA1. Single units respons
Autor:
Carolyn M. Sawyer, Yves Boucher, Earl Carstens, Austin W. Merrill, Mirela Iodi Carstens, Karen L. Zanotto
Publikováno v:
Neuroscience letters. 543
Many patients suffer from trigeminal neuralgia and other types of orofacial pain that are poorly treated, necessitating preclininal animal models for development of mechanisms-based therapies. The present study assessed capsaicin avoidance and other
Autor:
Amanda H. Klein, Susan Cheung, Earl Carstens, Margaret Ivanov, Karen L. Zanotto, Mirela Iodi Carstens, Carolyn M. Sawyer
Publikováno v:
Chemical senses. 36(2)
Menthol and cinnamaldehyde (CA) are plant-derived spices commonly used in oral hygiene products, chewing gum, and many other applications. However, little is known regarding their sensory interactions in the oral cavity. We used a human psychophysics
Autor:
Amanda H. Klein, Mirela Iodi Carstens, Karen L. Zanotto, Merab G. Tsagareli, Earl Carstens, G. Gurtskaia, Carolyn M. Sawyer, Nana Tsiklauri, E Abzianidze
TRPA1 agonists cinnamaldehyde (CA) and mustard oil (allyl isothiocyanate= AITC) induce heat hyperalgesia and mechanical allodynia in human skin, and sensitize responses of spinal and trigeminal dorsal horn neurons to noxious skin heating in rats. TRP
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::069e54ca7e66ad0518a9f600bf46de80
https://europepmc.org/articles/PMC2853256/
https://europepmc.org/articles/PMC2853256/
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 329(3)
Protease-activated receptor (PAR)-2 and PAR-4 are implicated in nonhistaminergic itch. We investigated dose dependence, tachyphylaxis, and cross-tachyphylaxis of itch-associated scratching elicited by intradermal injections of PAR-2 and PAR-4 agonist
Autor:
Karen L. Zanotto
Publikováno v:
Journal of Neurophysiology; Feb2007, Vol. 97 Issue 2, p966-978, 13p