Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Karen L. Osman"'
Autor:
David W. Cleary, Jessica Jones, Rebecca A. Gladstone, Karen L. Osman, Vanessa T. Devine, Johanna M. Jefferies, Stephen D. Bentley, Saul N. Faust, Stuart C. Clarke
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-11 (2022)
Abstract Streptococcus pneumoniae continues to cause significant disease burden. Whilst pneumococcal conjugate vaccines (PCV) have substantially reduced this burden, serotype replacement partially negates this success due to increased disease associa
Externí odkaz:
https://doaj.org/article/7f41cebd148a4f488ff778c756b319cf
Autor:
Denisa Bojkova, Philipp Reus, Leona Panosch, Marco Bechtel, Tamara Rothenburger, Joshua D. Kandler, Annika Pfeiffer, Julian U.G. Wagner, Mariana Shumliakivska, Stefanie Dimmeler, Ruth Olmer, Ulrich Martin, Florian W.R. Vondran, Tuna Toptan, Florian Rothweiler, Richard Zehner, Holger F. Rabenau, Karen L. Osman, Steven T. Pullan, Miles W. Carroll, Richard Stack, Sandra Ciesek, Mark N. Wass, Martin Michaelis, Jindrich Cinatl, Jr.
Publikováno v:
iScience, Vol 26, Iss 2, Pp 105944- (2023)
Summary: Reliable, easy-to-handle phenotypic screening platforms are needed for the identification of anti-SARS-CoV-2 compounds. Here, we present caspase 3/7 activity as a readout for monitoring the replication of SARS-CoV-2 isolates from different v
Externí odkaz:
https://doaj.org/article/4a88cf04c85349bf88133734b02945c5
Autor:
Simon G. P. Funnell, Babak Afrough, John James Baczenas, Neil Berry, Kevin R. Bewley, Rebecca Bradford, Clint Florence, Yann Le Duff, Mark Lewis, Ryan V. Moriarty, Shelby L. O. Connor, Karen L. Osman, Steven Pullan, Sujatha Rashid, Kevin S. Richards, Kimberly J. Stemple, Ivana Knezevic
Publikováno v:
npj Vaccines, Vol 6, Iss 1, Pp 1-5 (2021)
Abstract An array of SARS-CoV-2 virus variants have been isolated, propagated and used in in vitro assays, in vivo animal studies and human clinical trials. Observations of working stocks of SARS-CoV-2 suggest that sequential propagation in Vero cell
Externí odkaz:
https://doaj.org/article/d3e61c501c474ee4bce5627f7aeb9067
Autor:
Kathryn A. Ryan, Kevin R. Bewley, Susan A. Fotheringham, Gillian S. Slack, Phillip Brown, Yper Hall, Nadina I. Wand, Anthony C. Marriott, Breeze E. Cavell, Julia A. Tree, Lauren Allen, Marilyn J. Aram, Thomas J. Bean, Emily Brunt, Karen R. Buttigieg, Daniel P. Carter, Rebecca Cobb, Naomi S. Coombes, Steve J. Findlay-Wilson, Kerry J. Godwin, Karen E. Gooch, Jade Gouriet, Rachel Halkerston, Debbie J. Harris, Thomas H. Hender, Holly E. Humphries, Laura Hunter, Catherine M. K. Ho, Chelsea L. Kennard, Stephanie Leung, Stephanie Longet, Didier Ngabo, Karen L. Osman, Jemma Paterson, Elizabeth J. Penn, Steven T. Pullan, Emma Rayner, Oliver Skinner, Kimberley Steeds, Irene Taylor, Tom Tipton, Stephen Thomas, Carrie Turner, Robert J. Watson, Nathan R. Wiblin, Sue Charlton, Bassam Hallis, Julian A. Hiscox, Simon Funnell, Mike J. Dennis, Catherine J. Whittaker, Michael G. Catton, Julian Druce, Francisco J. Salguero, Miles W. Carroll
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
SARS-CoV-2 induces mild infection in ferret model. Here, Ryan et al. characterise optimal infection dosage inducing upper respiratory tract (UTR) viral shedding, progression time of viral shedding, and pathology in ferrets and finally provide evidenc
Externí odkaz:
https://doaj.org/article/a8afc90cbc2f4422be7dc5bc8923c3cf
Autor:
Caroline Carbonnelle, Marie Moroso, Delphine Pannetier, Sabine Godard, Stéphane Mély, Damien Thomas, Aurélie Duthey, Ophélie Jourjon, Orianne Lacroix, Béatrice Labrosse, Hervé Raoul, Karen L. Osman, Francisco J. Salguero, Yper Hall, Carol L. Sabourin, Michael J. Merchlinsky, James P. Long, Lindsay A. Parish, Daniel N. Wolfe
Publikováno v:
Vaccines, Vol 10, Iss 6, p 963 (2022)
Sudan ebolavirus (SUDV) is one of four members of the Ebolavirus genus known to cause Ebola Virus Disease (EVD) in humans, which is characterized by hemorrhagic fever and a high case fatality rate. While licensed therapeutics and vaccines are availab
Externí odkaz:
https://doaj.org/article/1816bfa814204221a31360efa99236d1
Autor:
Karen L. Osman, Ivana Knezevic, Sujatha Rashid, Kimberly J. Stemple, John J. Baczenas, Neil Berry, Steven T. Pullan, Babak Afrough, Mark G. Lewis, Clint Florence, Simon G. P. Funnell, Rebecca Bradford, Yann Le Duff, Kevin S. Richards, Kevin R. Bewley, Ryan V. Moriarty, Shelby L. O. Connor
Publikováno v:
npj Vaccines, Vol 6, Iss 1, Pp 1-5 (2021)
NPJ Vaccines
NPJ Vaccines
An array of SARS-CoV-2 virus variants have been isolated, propagated and used in in vitro assays, in vivo animal studies and human clinical trials. Observations of working stocks of SARS-CoV-2 suggest that sequential propagation in Vero cells leads t
Autor:
Kathryn A. Ryan, Kevin R. Bewley, Robert J. Watson, Christopher Burton, Oliver Carnell, Breeze E. Cavell, Amy Challis, Naomi S. Coombes, Elizabeth R. Davies, Jack Edun-Huges, Kirsty Emery, Rachel Fell, Susan A. Fotheringham, Karen E. Gooch, Kathryn Gowan, Alastair Handley, Debbie J. Harris, Richard Hesp, Laura Hunter, Richard Humphreys, Rachel Johnson, Chelsea Kennard, Daniel Knott, Sian Lister, Daniel Morley, Didier Ngabo, Karen L. Osman, Jemma Paterson, Elizabeth J. Penn, Steven T. Pullan, Kevin S. Richards, Sian Summers, Stephen R. Thomas, Thomas Weldon, Nathan R. Wiblin, Emma L. Rayner, Richard T. Vipond, Bassam Hallis, Francisco J. Salguero, Simon G. P. Funnell, Yper Hall
Publikováno v:
PLOS Pathogens. 19:e1011293
The mutation profile of the SARS-CoV-2 Omicron (lineage BA.1) variant posed a concern for naturally acquired and vaccine-induced immunity. We investigated the ability of prior infection with an early SARS-CoV-2 ancestral isolate (Australia/VIC01/2020
Publikováno v:
Microbial genomics. 8(5)
Autor:
Caroline, Carbonnelle, Marie, Moroso, Delphine, Pannetier, Sabine, Godard, Stéphane, Mély, Damien, Thomas, Aurélie, Duthey, Ophélie, Jourjon, Orianne, Lacroix, Béatrice, Labrosse, Hervé, Raoul, Karen L, Osman, Francisco J, Salguero, Yper, Hall, Carol L, Sabourin, Michael J, Merchlinsky, James P, Long, Lindsay A, Parish, Daniel N, Wolfe
Publikováno v:
Vaccines. 10(6)
Autor:
Kathryn A. Ryan, Robert J. Watson, Kevin R. Bewley, Christopher Burton, Oliver Carnell, Breeze E. Cavell, Amy Challis, Naomi S. Coombes, Kirsty Emery, Rachel Fell, Susan A. Fotheringham, Karen E. Gooch, Kathryn Gowan, Alastair Handley, Debbie J. Harris, Richard Humphreys, Rachel Johnson, Daniel Knott, Sian Lister, Daniel Morley, Didier Ngabo, Karen L. Osman, Jemma Paterson, Elizabeth J. Penn, Steven T. Pullan, Kevin S. Richards, Imam Shaik, Sian Summers, Stephen R. Thomas, Thomas Weldon, Nathan R. Wiblin, Richard Vipond, Bassam Hallis, Simon G. P. Funnell, Yper Hall
The mutation profile of the SARS-CoV-2 Omicron variant poses a concern for naturally acquired and vaccine-induced immunity. We investigated the ability of prior infection with an early SARS-CoV-2, 99.99% identical to Wuhan-Hu-1, to protect against di
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cc142a0855eea8d783ac8d7353547ed8
https://doi.org/10.1101/2021.12.24.474081
https://doi.org/10.1101/2021.12.24.474081