Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Karen L. Novik"'
Autor:
Vardhman K Rakyan, Thomas Hildmann, Karen L Novik, Jörn Lewin, Jörg Tost, Antony V Cox, T Dan Andrews, Kevin L Howe, Thomas Otto, Alexander Olek, Judith Fischer, Ivo G Gut, Kurt Berlin, Stephan Beck
Publikováno v:
PLoS Biology, Vol 2, Iss 12, p e405 (2004)
The Human Epigenome Project aims to identify, catalogue, and interpret genome-wide DNA methylation phenomena. Occurring naturally on cytosine bases at cytosine-guanine dinucleotides, DNA methylation is intimately involved in diverse biological proces
Externí odkaz:
https://doaj.org/article/2cf00ba41d244a9caba9210bb644349d
Autor:
Payal Sipahimalani, John J. Spinelli, Randy D. Gascoyne, Karey Shumansky, Agnes S. Lai, Karen L. Novik, Amy C. MacArthur, Joseph M. Connors, Angela Brooks-Wilson, Stephen Leach, Richard P. Gallagher
Publikováno v:
Cancer Epidemiology, Biomarkers & Prevention. 16:1098-1106
Non–Hodgkin lymphoma (NHL) comprises a group of lymphoid tumors that have in common somatic translocations. H2AFX encodes a key histone involved in the detection of the DNA double-stranded breaks that can lead to translocations. H2afx is a dosage-d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a556d4ad0c0653d9f9785c9ebe1ecf2f
https://doi.org/10.1158/1055-9965.epi-06-0639
https://doi.org/10.1158/1055-9965.epi-06-0639
Autor:
Douglas F. Easton, Xiaoqing Chen, Karen L. Novik, Paul D.P. Pharoah, Georgia Chenevix-Trench, Adèle C. Green, Karen Redman, Annika Auranen, Amanda B. Spurdle, John L. Hopper, David M. Purdie, Alison M. Dunning, Catherine S. Healey, Bruce A.J. Ponder, Julian Lipscombe
Publikováno v:
International Journal of Cancer. 103:427-430
The BRCA2 372 HH genotype defined by the BRCA2 N372H nonconservative amino acid substitution polymorphism was recently reported to be associated with a small increased risk of breast cancer. We investigated whether this polymorphism was associated wi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b39ee9df2a9ddb0393e36e64bd0ab157
https://doi.org/10.1002/ijc.10814
https://doi.org/10.1002/ijc.10814
Autor:
Douglas F. Easton, Antonis C. Antoniou, Bruce A.J. Ponder, Paul D.P. Pharoah, Alison M. Dunning, Julian Lipscombe, Karen L. Novik, Bettina Kuschel, Nicholas E. Day, Simon McBride, Annika Auranen
Publikováno v:
Human Molecular Genetics. 11:1399-1407
We performed genetic association studies in a population-based breast cancer case–control study analysing polymorphisms in genes involved in homologous recombination (NBS1, RAD52, RAD51, XRCC2 and XRCC3) and non-homologous end-joining (KU70/80 and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4d765d2d229d839daa2b3710e782a0c
https://doi.org/10.1093/hmg/11.12.1399
https://doi.org/10.1093/hmg/11.12.1399
Autor:
Karen L. Novik, Angela Brooks-Wilson
Publikováno v:
Encyclopedia of Genetics, Genomics, Proteomics and Bioinformatics
Complex diseases affect a substantial proportion of the human population and are caused by multiple genetic and environmental effects. The association study is a means of identifying genetic variation that may be involved in complex disease etiology.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::13f1479859f13b4a6ecf6e74cbffc739
https://doi.org/10.1002/047001153x.g202305
https://doi.org/10.1002/047001153x.g202305
Autor:
Christy Waterfall, Annika Auranen, Richard A. DiCioccio, Claus Høgdall, Douglas F. Easton, Paul D.P. Pharoah, Bruce A.J. Ponder, Alison M. Dunning, Alice S. Whittemore, Susanne K. Kjaer, Karen L. Novik, John F. Stratton, Bettina Kuschel, Estrid Høgdall, SA Gayther, Honglin Song
Publikováno v:
International journal of cancer. 117(4)
DNA repair gene polymorphisms and mutations are known to influence cancer risk. We studied whether polymorphisms in DNA double strand break (DSB) repair genes are associated with epithelial ovarian cancer (EOC) risk. Up to 1,600 cases and 4,241 contr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::984c8e5fcaac0634bf57c211b991a9ab
https://pubmed.ncbi.nlm.nih.gov/15924337
https://pubmed.ncbi.nlm.nih.gov/15924337
Autor:
Alison M. Dunning, Louise Tee, Nicholas E. Day, Mitch Dowsett, Douglas F. Easton, Livia Kelemen, Paul D.P. Pharoah, Saeko Ogata, Bruce A.J. Ponder, Karen L. Novik, Robert Luben, Elizabeth Folkerd, Catherine S. Healey
Publikováno v:
Journal of the National Cancer Institute. 96(12)
Polymorphisms associated with circulating sex hormone levels in postmenopausal women Background: Reports suggest a relationship between circulating sex hormone levels and breast cancer risk, but genetic association studies have been inconclusive. We
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16be131b23113b3e5b5eb3e65d2ac1ae
https://pubmed.ncbi.nlm.nih.gov/15657347
https://pubmed.ncbi.nlm.nih.gov/15657347
Autor:
Paul D.P. Pharoah, Karen L. Novik, Louise Tee, Doug Easton, Bettina Kuschel, F. Durocher, Alison M. Dunning, B. A. J. Ponder, Annika Auranen, Julian Lipscombe
Publikováno v:
International Journal of Gynecologic Cancer. 13:7.1-7
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::baf8112458d7109ba30c557cac3a2d54
https://doi.org/10.1136/ijgc-00009577-200303001-00021
https://doi.org/10.1136/ijgc-00009577-200303001-00021