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pro vyhledávání: '"Karen L. Kachel"'
Publikováno v:
Molecular Carcinogenesis. 47:538-553
Endocytic pathways have been implicated in polyamine transport in mammalian cells, but specific mechanisms have not been described. We have shown that expression of a dominant negative (DN) form of the GTPase Dynamin, but not Eps15, diminished polyam
Autor:
Natalia A, Ignatenko, Hagit F, Yerushalmi, Ritu, Pandey, Karen L, Kachel, David E, Stringer, Laurence J, Marton, Eugene W, Gerner
Publikováno v:
Cancer genomicsproteomics. 6(3)
The conformationally restricted polyamine analog PG-11047 has significant growth inhibitory activity against prostate and lung cancer cell lines and is currently under evaluation in several clinical trials, both alone and in combination with other dr