Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Karen L. Davis Bruno"'
Autor:
Xilin Li, Xiaobo He, Yuan Le, Xiaoqing Guo, Matthew S. Bryant, Aisar H. Atrakchi, Timothy J. McGovern, Karen L. Davis-Bruno, David A. Keire, Robert H. Heflich, Nan Mei
Publikováno v:
Archives of Toxicology. 96:3077-3089
Autor:
Xilin Li, Yuan Le, Ji-Eun Seo, Xiaoqing Guo, Yuxi Li, Si Chen, Roberta A. Mittelstaedt, Nyosha Moore, Sharon Guerrero, Audrey Sims, Sruthi T. King, Aisar H. Atrakchi, Timothy J. McGovern, Karen L. Davis-Bruno, David A. Keire, Rosalie K. Elespuru, Robert H. Heflich, Nan Mei
Publikováno v:
Regulatory Toxicology and Pharmacology. 141:105410
Autor:
Xilin, Li, Xiaobo, He, Yuan, Le, Xiaoqing, Guo, Matthew S, Bryant, Aisar H, Atrakchi, Timothy J, McGovern, Karen L, Davis-Bruno, David A, Keire, Robert H, Heflich, Nan, Mei
Publikováno v:
Archives of toxicology. 96(11)
Many nitrosamines are recognized as mutagens and potent rodent carcinogens. Over the past few years, nitrosamine impurities have been detected in various drugs leading to drug recalls. Although nitrosamines are included in a 'cohort of concern' becau
Autor:
Amy M. Avila, David B. Carlson, Jill C. Merrill, Jia Yao, Paul Brown, Emily Place, Todd Bourcier, Shwu-Luan Lee, Wafa Harrouk, Ronald L. Wange, Ilona Bebenek, Muriel Saulnier, Karen L. Davis Bruno, Ikram Elayan, Donna L. Mendrick, Dong Zhao, John Dubinion, Jackye Peretz, Jessica A. Bonzo
Publikováno v:
Regulatory Toxicology and Pharmacology. 114:104662
Nonclinical testing of human pharmaceuticals is conducted to assess the safety of compounds to be studied in human clinical trials and for marketing of new drugs. Although there is no exact number and type of nonclinical studies required for safety a
Autor:
GRAHAM P. ALLAWAY, KAREN L. DAVIS-BRUNO, GARY A. BEAUDRY, ELISA B. GARCIA, EMILY L. WONG, ANDREW M. RYDER, KARL W. HASEL, MARIE-CLAIRE GAUDUIN, RICHARD A. KOUP, J. STEVEN McDOUGAL, PAUL J. MADDON
Publikováno v:
AIDS research and human retroviruses. 11(5)
CD4-IgG2 is a novel fusion protein comprising human IgG2 in which the Fv portions of both heavy and light chains have been replaced by the V1 and V2 domains of human CD4. This tetrameric protein is being developed as an immunoprophylactic agent to re