Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Karen L. Bride"'
Autor:
Karen L. Bride, Hai Hu, Anastasia Tikhonova, Tori J. Fuller, Tiffaney L. Vincent, Rawan Shraim, Marilyn M. Li, William L. Carroll, Elizabeth A. Raetz, Iannis Aifantis, David T. Teachey
Publikováno v:
Haematologica, Vol 107, Iss 8 (2021)
Despite improvements in outcomes for children with B- and T-cell acute lymphoblastic leukemia (B-ALL and T-ALL), patients with resistant or relapsed disease fare poorly. Previous studies have demonstrated the essential role of cyclin D3 in T-ALL dise
Externí odkaz:
https://doaj.org/article/5de625346f4e411da1839face46afb2f
Autor:
Phillip L Guichet, Sylwia Jasinski, Karen L Bride, Francis Andrew De Los Reyes, Laura Malaga-Dieguez, Tania Ahuja, Amish Patel
Publikováno v:
Journal of pediatric hematology/oncology. 43(4)
Renal vein thrombosis is the most common non-catheter-associated venous thromboembolism event in neonates, accounting for up to 20% of cases. Although mortality rates are lower than a variety of other forms of pediatric thrombosis, renal vein thrombi
Autor:
Wei-Che Ko, John E. Harris, Zhaozhao Jiang, Purvi Mande, Katherine A. Fitzgerald, Karen Dresser, Keyon Taravati, Michael Rosenblum, Bahar Zirak, Ann Marshak-Rothstein, Tia Bumpus Brodeur, April Deng, Karen L. Bride, Rachel Ettinger
Publikováno v:
Journal of Clinical Investigation. 128:2966-2978
Toll-like receptors TLR7 and TLR9 are both implicated in the activation of autoreactive B cells and other cell types associated with systemic lupus erythematosus (SLE) pathogenesis. However, Tlr9–/– autoimmune-prone strains paradoxically develop
Publikováno v:
Hematopoietic Stem Cell Transplantation for the Pediatric Hematologist/Oncologist ISBN: 9783319631448
The incidence of life-threatening and/or opportunistic infections in the hematopoietic stem cell transplantation (HSCT) setting varies widely. Despite improved microbial detection methods and supportive care, infection remains one of the leading caus
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::acf6cec98e45712e44bb186bc83a3118
https://doi.org/10.1007/978-3-319-63146-2_17
https://doi.org/10.1007/978-3-319-63146-2_17
Publikováno v:
Hematopoietic Stem Cell Transplantation for the Pediatric Hematologist/Oncologist ISBN: 9783319631448
Graft-versus-host disease (GvHD) results from the recognition of the hematopoietic stem cell transplantation (HSCT) recipient’s tissues as being foreign by immunocompetent donor T cells. GvHD remains a major cause of HSCT-related morbidity and mort
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3374ce8e90b5a2f05dff9678a8b957e3
https://doi.org/10.1007/978-3-319-63146-2_18
https://doi.org/10.1007/978-3-319-63146-2_18
Autor:
Karen L. Bride, Michele Paessler, Michele P. Lambert, Alicia McDonnell, Derick Lim, Char Witmer
Publikováno v:
Pediatric bloodcancer. 65(2)
Background Differentiating childhood immune thrombocytopenia (ITP) from other cause of thrombocytopenia remains a diagnosis of exclusion. Additionally factors that predict bleeding risk for those patients with ITP are currently not well understood. P
Autor:
Richard Aplenc, Tori Fuller, Brent L. Wood, Soo Yeon Im, Stuart S. Winter, Robin Carson, David T. Teachey, Tiffaney Vincent, Stephen P. Hunger, Stephan A. Grupp, Tina Glisovic-Aplenc, Kimberly P. Dunsmore, William L. Carroll, Mignon L. Loh, Terzah M. Horton, Michelle L. Hermiston, Elizabeth A. Raetz, Yunfeng Dai, Shannon L. Maude, Karen L. Bride, Meenakshi Devidas, David M. Barrett
Publikováno v:
Blood. 131(9)
As a consequence of acquired or intrinsic disease resistance, the prognosis for patients with relapsed or refractory T-cell acute lymphoblastic leukemia (T-ALL) is dismal. Novel, less toxic drugs are clearly needed. One of the most promising emerging
Autor:
Loan Hsieh, Mohamad Badawi, Omar Niss, Karen L. Bride, Jill S. Menell, Cynthia J. Rutherford, Mary Risinger, Vandy Black, Katie Giger Seu, Wenying Zhang, Theodosia A. Kalfa, Charles T. Quinn, Renee C. Prins
Publikováno v:
Blood. 132:1040-1040
Hereditary xerocytosis (HX) is a rare autosomal dominant hemolytic anemia caused by mutations in the mechanosensitive cation channel PIEZO1 or, less commonly, in the Ca2+-gated K+ channel KCNN4 (Gardos channel). It is a clinically heterogeneous condi
Autor:
Karen L. Bride, David T. Teachey
Publikováno v:
F1000Research
Autoimmune lymphoproliferative syndrome (ALPS) is an inherited syndrome characterized by abnormal lymphocyte survival caused by failure of apoptotic mechanisms to maintain lymphocyte homeostasis. This failure leads to the clinical manifestations of n
Autor:
Michele P. Lambert, Kim Smith-Whitley, James T. Casper, Tiffaney Vincent, Catherine S. Manno, Alix E. Seif, Jack J. Bleesing, Karen L. Bride, David T. Teachey, Stephan A. Grupp
Publikováno v:
Blood. 127(1)
Patients with autoimmune multilineage cytopenias are often refractory to standard therapies requiring chronic immunosuppression with medications with limited efficacy and high toxicity. We present data on 30 patients treated on a multicenter prospect