Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Karen L. Allendoerfer"'
Autor:
David R. Tomlinson, Jean Dominique Delcroix, Renee I. Shapiro, Rigel Ranciato, Jason D. Freshwater, Frederick R. Taylor, Monica L. Burgers, Andrew P. Mizisin, Thomas Engber, Nigel A. Calcutt, Henryk Dudek, Alicia Middlemas, Alphonse Galdes, Karen L. Allendoerfer, Lee L. Rubin, Kathy Strauch
Publikováno v:
Journal of Clinical Investigation. 111:507-514
Hedgehog proteins modulate development and patterning of the embryonic nervous system. As expression of desert hedgehog and the hedgehog receptor, patched-1, persist in the postnatal and adult peripheral nerves, the hedgehog pathway may have a role i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce4d71bb1ba3b9443143906b4eb35848
https://doi.org/10.1172/jci200315792
https://doi.org/10.1172/jci200315792
Autor:
Nagesh K. Mahanthappa, Irina Karavanova, Karen L. Allendoerfer, Kevin P. Williams, Jennifer Reilly
Publikováno v:
Molecular and Cellular Neuroscience. 19:88-96
In ventromedial cells of the developing CNS, Sonic hedgehog (Shh) has been shown to affect precursor proliferation, phenotype determination, and survival. Here we show that Shh and its receptor, Ptc-1, are expressed in the adult rat basal forebrain,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f3ccb239baa96506fd321e60055e621
https://doi.org/10.1006/mcne.2001.1063
https://doi.org/10.1006/mcne.2001.1063
Publikováno v:
Developmental Biology. 211:208-219
The Lewis-X (LeX) carbohydrate epitope, recognized by the FORSE-1 monoclonal antibody (mAb), shares expression boundaries with neural regulatory genes and may be involved in patterning the neural tube by creating domains of differential cell adhesion
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d23d114dbabf7ff28ec5e93fadd1308a
https://doi.org/10.1006/dbio.1999.9308
https://doi.org/10.1006/dbio.1999.9308
Changing Patterns of Expression and Subcellular Localization of TrkB in the Developing Visual System
Autor:
Andrew A. Welcher, Karen L. Allendoerfer, Monte J. Radeke, Robert J. Cabelli, Stuart C. Feinstein, Carla J. Shatz
Publikováno v:
The Journal of Neuroscience. 16:7965-7980
Neurotrophins play important roles in the survival, differentiation, and maintenance of CNS neurons. To begin to investigate specific roles for these factors in the mammalian visual system, we have examined the cellular localization of the neurotroph
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63f5d2dd71383825a135d96a59769ba8
https://doi.org/10.1523/jneurosci.16-24-07965.1996
https://doi.org/10.1523/jneurosci.16-24-07965.1996
Publikováno v:
The Journal of Neuroscience. 14:1795-1811
Cell division, cell death, and remodeling of connections are major features of the construction of the mammalian CNS. We have begun to address the role of neurotrophins in these events through characterization of the expression of their receptors in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ce21d71d53ea4c3dd5f4d679f3b2369
https://doi.org/10.1523/jneurosci.14-03-01795.1994
https://doi.org/10.1523/jneurosci.14-03-01795.1994
Autor:
Karen L. Allendoerfer, Susan Lindquist
Publikováno v:
Intracellular Traffic and Neurodegenerative Disorders ISBN: 9783540879404
We have developed simple cellular models of complex neurodegenerative diseases by over-expressing disease-associated human proteins in yeast. By combining the unique power of yeast genetics with the highly conserved biology of protein homeostasis in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2c51431053d86fb93b08a4063846391e
https://doi.org/10.1007/978-3-540-87941-1_4
https://doi.org/10.1007/978-3-540-87941-1_4
Publisher Summary This chapter explores yeast cells as a discovery platform for Parkinson's disease (PD) and finding genetic factors and chemical compounds that modify the toxicity of proteins that are prone to misfoldings and producing toxic gain-of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1be6e614347101df650ecbdedf729ed1
https://doi.org/10.1016/b978-0-12-374028-1.00038-5
https://doi.org/10.1016/b978-0-12-374028-1.00038-5
Autor:
Douglas W. Losordo, Roberto Pola, Marta Bosch-Marce, Young Sup Yoon, Cynthia Curry, William E. Munger, Marcy Silver, Kengo Fukushima Kusano, Takayuki Asahara, Rudolf Kirchmair, Karen L. Allendoerfer, Marianne Kearney
Publikováno v:
Arteriosclerosis, thrombosis, and vascular biology. 24(11)
Objective— The embryonic morphogen sonic hedgehog (SHh) has been shown to induce neovascularization of ischemic tissue but has not been shown to play a role in regulating vascular nerve supply. Accordingly, we investigated the hypothesis that syste
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a823a860c7a81805a93a6ca515305598
https://pubmed.ncbi.nlm.nih.gov/15358602
https://pubmed.ncbi.nlm.nih.gov/15358602
Autor:
Karen L, Allendoerfer, Henryk, Dudek
Publikováno v:
Current opinion in investigational drugs (London, England : 2000). 3(12)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::4ea6445bb8349e629eeee033134476a9
https://pubmed.ncbi.nlm.nih.gov/12528310
https://pubmed.ncbi.nlm.nih.gov/12528310
Publikováno v:
Molecular and cellular neurosciences. 6(4)
A key problem in nervous system development is how distinct subpopulations of progenitor cells give rise to different adult brain structures. The labeling pattern of the FORSE-1 antibody subdivides the neuroepithelium of the embryonic forebrain into
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6cb25ec0d28cf9828a6b6f1ec820e63e
https://pubmed.ncbi.nlm.nih.gov/8846006
https://pubmed.ncbi.nlm.nih.gov/8846006