Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Karen Kwai Har Li"'
Autor:
Karen Kwai Har Li, Kam Sze Tsang, Chi Kong Li, Patrick Man Pan Yuen, Rui-Jun Su, Tai F. Fok, Mo Yang, Xiao-Bing Zhang
Publikováno v:
Bone Marrow Transplantation. 27:1075-1080
Infusion of ex vivo expanded megakaryocytic (MK) progenitor cells is a strategy for shortening the duration of thrombocytopenia after haematopoietic stem cell transplantation. The cell dose after expansion has emerged as a critical factor for achievi
Publikováno v:
Bone Marrow Transplantation. 27:133-138
The number of nucleated cells infused into the recipient of a cord blood (CB) transplant has emerged as the most important factor affecting the probability and speed of engraftment. At present, there is no international consensus on the procedure of
Autor:
Samuel S. M. Sun, Lawrence C.-M. Chiu, Karen Kwai-Har Li, Vincent E.C. Ooi, Kam Tong Leung, Paul K.S. Chan
Publikováno v:
Carcinogenesis. 29(3)
T-cell acute lymphoblastic leukemias (T-ALLs) are highly malignant tumors with 20% of patients continues to fail therapy, in part due to chemoresistance of T-ALL cells via largely unknown mechanisms. Here, we showed that lack of Bcl-2-interacting med
Autor:
Anthony E. James, Xiao-Bing Zhang, A C Lam, S M Lee, Patrick Man Pan Yuen, Karen Kwai Har Li, Tai F. Fok, Chi Kong Li
Publikováno v:
Bone marrow transplantation. 30(9)
Our prior study demonstrated that neonatal blood (NB) contained hematopoietic stem and progenitor cells that declined rapidly after birth. To validate that NB is a source of functional stem cells, we characterized this population in terms of cobblest
Autor:
Kam Sze Tsang, M. M. K. Shing, D. C. Zhao, Vincent Lee, Patrick Man Pan Yuen, D. H. Lai, Annie Wong, Karen Kwai Har Li, K. W. Chik, Chi Kong Li
Publikováno v:
Bone marrow transplantation. 25(9)
The optimal dose and schedule of G-CSF for mobilization of peripheral blood stem cells (PBSC) is not well defined. G-CSF mobilization was performed in a group of healthy donors and paediatric patients for autologous back-up before receiving allogenei
Autor:
Yum Shing Wong, Vincent E.C. Ooi, Karen Kwai Har Li, Lawrence Chi Ming Chiu, Paul K.S. Chan, Kam Tong Leung, Samuel S. M. Sun
Publikováno v:
Blood. 110:2372-2372
Despite progress in the development of effective treatments against T-cell acute lymphoblastic leukemia (T-ALL), about 20% of patients still exhibit poor response to the current chemotherapeutic regimens and the cause of treatment failure in these pa
Autor:
Linda Shiou Mei Ooi, Kam Sze Tsang, Lawrence Chi Ming Chiu, Xiao-Bing Zhang, Carmen Ka Yee Chuen, Vincent E.C. Ooi, Kathy Yuen Yee Chan, Kam Tong Leung, Karen Kwai Har Li, Audrey Carmen Lam
Publikováno v:
Blood. 110:1197-1197
Ex vivo expansion of hematopoietic stem and progenitor cells in cytokine combinations is effective in promoting differentiation and proliferation of multilineage progenitor cells, but often results in reduction of self-renewable stem cells. In this s
Autor:
Mo Yang, Pak Cheung Ng, Ai Guo Liu Liu, Tai Fai Fok, Nga Hin Pong, Chi Kong Li, Wei Zhe Huang, Karen Kwai Har Li
Publikováno v:
Blood. 106:2159-2159
To date, there is no ideal treatment for thrombocytopenia. We have proposed a possible mechanism of serotonin (5-HT) on megakaryocyte (MK) differentiation and platelet formation (Yang et al, Blood, 2003 suppl). The root of polygonum multiflorum thunb
Autor:
Nga Hin Pong, Mo Yang, Ai Guo Liu, Tai Fai Fok, Pak Cheung Ng, Karen Kwai Har Li, Xiao Jing Li, Chi Kong Li, Wei Zhe Huang
Publikováno v:
Blood. 106:2158-2158
We have reported that serotonin (5-hydroxytryptamine, 5-HT) significantly stimulates megakaryocytopoiesis. It has been known that platelet count can be increased in stress conditions and serotonin has an effect on actin re-organization and promotes n
Autor:
Mei Lian Chen, Mo Yang, Xiao Feng Li, Qing Wen Wang, Karen Kwai Har Li, Zheng Xian He, Wei Xiong
Publikováno v:
Blood. 106:3859-3859
Human cytomegalovirus (HCMV) infection can cause delayed leukocyte recovery after bone marrow transplantation and often associated with suppression of granulocyte/macrophage progenitor. Leukocyte lineage may be one of the major sites of HCMV infectio