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Environmental enrichment, administered after establishment of cocaine self-administration, reduces lever pressing in extinction and during a cocaine context renewal test

Autor: Karen Kest, Priscila Hachimine-Semprebom, Robert Ranaldi, Margaret R. Zellner

Publikováno v: Behavioural Pharmacology. 22:347-353

The objective of this study was to test the hypothesis that environmental enrichment (EE) administered to rats previously trained to self-administer cocaine would reduce responding in extinction and in a cocaine-context renewal test. Long-Evans male

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c35eed70b1b24f1cfbd6f0e34ce608c0
https://doi.org/10.1097/fbp.0b013e3283487365

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The effects of VTA NMDA receptor antagonism on reward-related learning and associated c-fos expression in forebrain

Autor: Yvonne Cruz, Jonathan Muller, Karen Kest, Margaret R. Zellner, Daniel Lubelski, Michelle Saliba, Robert Ranaldi

Publikováno v: Behavioural Brain Research. 216:424-432

The mechanisms whereby reward-associated stimuli come to function as conditioned stimuli and acquire the capacity to activate the same neural regions activated by primary rewards (i.e., dopamine terminal regions) is not fully understood. We hypothesi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00cdd64fce6564d98534a90ca48665f0
https://doi.org/10.1016/j.bbr.2010.08.026

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A food-associated CS activates c-Fos in VTA DA neurons and elicits conditioned approach

Autor: Robert Ranaldi, Ivonne Cruz, Karen Kest, Dan Hong Chen, Ewa Galaj

Publikováno v: Behavioural brain research. 235(2)

Neutral stimuli associated with unconditioned stimuli (USs) acquire the ability to act as conditioned stimuli (CSs), which can elicit behaviors similar to the US with which they are associated. The neural mechanisms by which this occurs are not fully

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1554ded18db4fc8b520eff223fd25d21
https://pubmed.ncbi.nlm.nih.gov/22963991

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Repeated heroin in rats produces locomotor sensitization and enhances appetitive Pavlovian and instrumental learning involving food reward

Autor: Matthew Fein, Andrew R. Delamater, Karen Kest, Jonathan Egan, Robert Ranaldi

Publikováno v: Pharmacology, biochemistry, and behavior. 91(3)

We tested the hypothesis that sensitization to heroin enhances appetitive motivational processes involving food reward. In Experiment 1, sixteen rats were exposed to positive pairings of a light stimulus and food for 4 consecutive daily sessions. The

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dfe7b32678c862fa0fa9fb66483dc17e
https://pubmed.ncbi.nlm.nih.gov/18755208

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