Zobrazeno 1 - 10
of 160
pro vyhledávání: '"Karen K. Szumlinski"'
Publikováno v:
Frontiers in Psychiatry, Vol 15 (2024)
IntroductionRepeated exposure to methamphetamine (MA) in laboratory rodents induces a sensitization of glutamate release within the corticoaccumbens pathway that drives both the rewarding and reinforcing properties of this highly addictive drug. Such
Externí odkaz:
https://doaj.org/article/96ce42dcb86a48649ec6c687e1a6241e
Autor:
Karen K. Szumlinski, Jessica N. Herbert, Brenda Mejia Espinoza, Lauren E. Madory, Samantha L. Scudder
Publikováno v:
Addiction Neuroscience, Vol 7, Iss , Pp 100099- (2023)
Heavy drinking can induce early-onset dementia and increase the likelihood of the progression and severity of Alzheimer's Disease and related dementias (ADRD). Recently, we showed that alcohol-drinking by mature adult C57BL/6J mice induces more signs
Externí odkaz:
https://doaj.org/article/33d0b5c81b69458e964496a386b8fb45
Autor:
Christopher J. E. Denning, Lauren E. Madory, Jessica N. Herbert, Ryan A. Cabrera, Karen K. Szumlinski
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 3, p 1928 (2024)
Methamphetamine (MA) is a highly addictive drug, and MA use disorder is often comorbid with anxiety and cognitive impairment. These comorbid conditions are theorized to reflect glutamate-related neurotoxicity within the frontal cortical regions. Howe
Externí odkaz:
https://doaj.org/article/fffe02464e334e46a4a58fae725ee58c
Autor:
C. Leonardo Jimenez Chavez, Eliyana Van Doren, Gavin Scheldrup, Emely Rivera, Jose Torres-Gonzalez, Jessica N. Herbert, Christopher J. E. Denning, Sarah Khorsandi, Andrew Garcia, Marian Castro, Karen K. Szumlinski
Publikováno v:
Frontiers in Behavioral Neuroscience, Vol 17 (2023)
IntroductionAlcohol abuse is a risk factor for affective and cognitive disorders, with evidence indicating that adolescent-onset excessive drinking can result in long-term deficiencies in emotional regulation and cognition, with females more suscepti
Externí odkaz:
https://doaj.org/article/b8c02a77d95740539d4044dfb0ec2bdd
Autor:
Laura L. Huerta Sanchez, Mathangi Sankaran, Taylor L. Li, Hoa Doan, Alvin Chiu, Eleanora Shulman, Gabriella Shab, Tod E. Kippin, Karen K. Szumlinski
Publikováno v:
Frontiers in Psychiatry, Vol 13 (2023)
IntroductionIncubation of drug-craving refers to a time-dependent increase in drug cue-elicited craving that occurs during protracted withdrawal. Historically, rat models of incubated cocaine craving employed extended-access (typically 6 h/day) intra
Externí odkaz:
https://doaj.org/article/0e827c78d55243ca9b572819769fabeb
Autor:
Sierra M. Webb, Arianne D. Sacramento, Megan A. McCloskey, Melissa G. Wroten, Kyle L. Ploense, Tod E. Kippin, Osnat Ben-Shahar, Karen K. Szumlinski
Publikováno v:
Addiction Neuroscience, Vol 3, Iss , Pp 100030- (2022)
Externí odkaz:
https://doaj.org/article/dd95140dc9b9497ea24d524a966698a2
Autor:
C. Leonardo Jimenez Chavez, Eliyana Van Doren, Jacob Matalon, Nneoma Ogele, Aadithya Kharwa, Lauren Madory, Ida Kazerani, Jessica Herbert, Jose Torres-Gonzalez, Emely Rivera, Karen K. Szumlinski
Publikováno v:
Frontiers in Behavioral Neuroscience, Vol 16 (2022)
A history of heavy drinking increases vulnerability to, and the severity of, Alzheimer’s disease (AD) and related dementias, with alcohol use disorder identified as the strongest modifiable risk factor for early-onset dementia. Heavy drinking has i
Externí odkaz:
https://doaj.org/article/af9bfe3c1cf84f4da21e5ed274bc0136
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 9, p 4872 (2022)
Methamphetamine (MA) is a highly addictive psychostimulant drug, and the number of MA-related overdose deaths has reached epidemic proportions. Repeated MA exposure induces a robust and persistent neuroinflammatory response, and the evidence supports
Externí odkaz:
https://doaj.org/article/aa27db90dacc41e5807c89f5505cce3c
Autor:
Chelsea N. Brown, Elissa K. Fultz, Sami Ferdousian, Sarina Rogers, Elijah Lustig, Ariana Page, John R. Shahin, Daniel M. Flaherty, Georg Von Jonquieres, Camron D. Bryant, Tod E. Kippin, Karen K. Szumlinski
Publikováno v:
Frontiers in Psychiatry, Vol 11 (2020)
Problems associated with the abuse of amphetamine-type stimulants, including methamphetamine (MA), pose serious health and socioeconomic issues world-wide. While it is well-established that MA’s psychopharmacological effects involve interactions wi
Externí odkaz:
https://doaj.org/article/bc6c7e4790e748cc85b9c6cab48038e9
Publikováno v:
Substance Abuse: Research and Treatment, Vol 14 (2020)
Methamphetamine (MA) and alcohol use disorders exhibit a high degree of co-morbidity and sequential alcohol-MA mixing increases risk for co-abuse. Recently, we reported greater MA-conditioned reward in male C57BL/6J mice with a prior history of binge
Externí odkaz:
https://doaj.org/article/9243cf3213f0439fa67d2030e5d736bc