Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Karen K. Kuropatwinski"'
Autor:
Karen K. Kuropatwinski, Olga V. Chernova, Bryan Gillard, Anatoli S. Gleiberman, Michael T. Moser, Michelle Wrobel, Ilia Toshkov, Ellen Karasik, Andrei V. Gudkov, Ekaterina L. Andrianova, Barbara A. Foster, Marina P. Antoch
Publikováno v:
Oncotarget
// Marina P. Antoch 1 , Michelle Wrobel 2 , Bryan Gillard 1 , Karen K. Kuropatwinski 1 , Ilia Toshkov 2 , Anatoli S. Gleiberman 2 , Ellen Karasik 1 , Michael T. Moser 1 , Barbara A. Foster 1 , Ekaterina L. Andrianova 2 , Olga V. Chernova 2 and Andrei
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b172ce04a3f86af6a0bf8cffd338b8b1
http://europepmc.org/articles/PMC7170500
http://europepmc.org/articles/PMC7170500
Autor:
Olga B. Chernova, Mikhail V. Blagosklonny, Karen K. Kuropatwinski, Marina P. Antoch, Alexander Polinsky, Ilia Toshkov, Andrei V. Gudkov, Maria Comas
Publikováno v:
Aging (Albany NY)
The nutrient-sensing mTOR (mammalian Target of Rapamycin) pathway regulates cellular metabolism, growth functions, and proliferation and is involved in age-related diseases including cancer, type 2 diabetes, neurodegeneration and cardiovascular disea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d1f7879fdb3d878930f6310256ffaa2
https://doi.org/10.18632/aging.100496
https://doi.org/10.18632/aging.100496
Publikováno v:
Cell Cycle. 8:4138-4146
The circadian clock regulates biological processes from gene expression to organism behavior in a precise, sustained rhythm that is generated at the unicellular level by coordinated function of interlocked transcriptional feedback loops and post-tran
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2469f6701a7df0a90b8d5a9e4cdfd5e
https://doi.org/10.4161/cc.8.24.10273
https://doi.org/10.4161/cc.8.24.10273
Autor:
Xiao-Ning Guo, Rebecca Rose, Ashwani Rajput, Alexander Beko, Karen K. Kuropatwinski, Jing Wang, Michael G. Brattain, Jennie Hauser, Charles LeVea, Robert M. Hoffman
Publikováno v:
Cancer Research. 67:5851-5858
Mutations in the PIK3CA gene are common in human cancers, including colon cancer. We compared two pairs of colon cancer cells (HCT116 and DLD1) bearing only the wild-type (WT) or mutant (MUT) PIK3CA allele for their survival capacity under stress con
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a73e11bc0042f637eda192ceab01164
https://doi.org/10.1158/0008-5472.can-07-0049
https://doi.org/10.1158/0008-5472.can-07-0049
Autor:
Julie L.C. Kan, Neil W. Gibson, Karen K. Kuropatwinski, Jing Wang, Yunfei Zhou, Michael R. Rossi, Alexis Conway, John K. Cowell, James K V Willson, Michael G. Brattain, Jennie Hauser
Publikováno v:
Molecular Cancer Therapeutics. 6:1143-1150
PIK3CA, encoding the p110α catalytic subunit of phosphatidylinositol 3-kinase (PI3K), is mutated in a variety of human cancers. We screened the colon cancer cell lines previously established in our laboratory for PIK3CA mutations and found that four
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d16eb4e77a07cb97c0dad3fc54aa9f3f
https://doi.org/10.1158/1535-7163.mct-06-0555
https://doi.org/10.1158/1535-7163.mct-06-0555
Publikováno v:
Journal of Biological Chemistry. 272:4065-4071
The leptin receptor (OB-R) mediates the weight regulatory effects of the adipocyte secreted hormone leptin (OB). Previously we have shown that the long form of OB-R, expressed predominantly in the hypothalamus, can mediate ligand-induced activation o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c983dc8e34badbbf0cba26f3869d3a0f
https://doi.org/10.1074/jbc.272.7.4065
https://doi.org/10.1074/jbc.272.7.4065
Publikováno v:
Cell cycle (Georgetown, Tex.). 12(23)
There is a growing body of evidence that components of the circadian clock are involved in modulation of numerous signaling pathways, and that clock deregulation due to environmental or genetic factors contributes to the development of various pathol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eef2a344a51dbdc348e9019b37a30c5f
https://pubmed.ncbi.nlm.nih.gov/24496331
https://pubmed.ncbi.nlm.nih.gov/24496331
Autor:
Anatoli S. Gleiberman, Krysta A. Deluca, Andrei V. Gudkov, Alexander V. Gasparian, Mary L. Spengler, Karen K. Kuropatwinski, Marina P. Antoch, Natalia Fedtsova, Natalia M. Artemicheva, Maria Comas, Ilya Gitlin
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 109(37)
The circadian clock controls many physiological parameters including immune response to infectious agents, which is mediated by activation of the transcription factor NF-κB. It is widely accepted that circadian regulation is based on periodic change
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f761627220704cfb08cc5179fb45fa3
https://pubmed.ncbi.nlm.nih.gov/22895791
https://pubmed.ncbi.nlm.nih.gov/22895791
Autor:
Marilyn Jackson, Karen K. Kuropatwinski, Anatoly S. Gleiberman, Natalia Fedtsova, Mikhail V. Chernov, Youcef M. Rustum, Mary L. Spengler, Yan Hu, Maria Comas, Andrei V. Gudkov, Marina P. Antoch
Publikováno v:
Oncotarget
Yan Hu 1 , Mary L. Spengler 1 , Karen K. Kuropatwinski 1 , Maria Comas-Soberats 1 , Marilyn Jackson 1 , Mikhail V. Chernov 2,3 , Anatoly S. Gleiberman 4 , Natalia Fedtsova 2 , Youcef M. Rustum 5 , Andrei V. Gudkov 2 , and Marina P. Antoch 1 1 Departm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45953a8a2f1ef3959f206c562ffaa4b6
https://pubmed.ncbi.nlm.nih.gov/22249125
https://pubmed.ncbi.nlm.nih.gov/22249125
Autor:
Jennie Hauser, Rebecca Rose, Alexander Beko, Feng-Lei Sun, Xiao-Qiong Liu, Charles LeVea, Elizabeth Sharratt, Julie L.C. Kan, Neil W. Gibson, Karen K. Kuropatwinski, Michael G. Brattain, Jing Wang, Lisa E. Brattain, David M. Keane, Ivan Dominquez, Ashwani Rajput
Publikováno v:
The Journal of biological chemistry. 284(16)
Abnormal accumulation and activation of receptor tyrosine kinase Ron (recepteur d'origine nantais) has been demonstrated in a variety of primary human cancers. We show that RNA interference-mediated knockdown of Ron kinase in a highly tumorigenic col
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63f74a8f4abd24bfe49872803e850476
https://pubmed.ncbi.nlm.nih.gov/19224914
https://pubmed.ncbi.nlm.nih.gov/19224914