Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Karen J. Light-Wahl"'
Autor:
Paul L. Richardson, Alanna Schepartz, Margaret L. Gross, Richard D. Smith, Karen J. Light-Wahl
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 4:2133-2138
We describe an efficient, four-step synthesis of an N 4 -modified cytidine phosphoramidite reagent ( 1 ) that permits nonnative functionality to be introduced into a synthetic oligoribonucleotide. This reagent was used to prepare a 377-nt E. coli M1
Publikováno v:
Journal of the American Chemical Society. 116:5271-5278
The noncovalent tetrameric active forms of avidin, concanavalin A (Con A), and adult human hemoglobin (HbA[sub 0]) can be observed intact in the gas phase by electrospray ionization mass spectrometry (ESI-MS). The atmosphere-vacuum ESI interface cond
Publikováno v:
Journal of the American Society for Mass Spectrometry. 5:201-204
Intact avidin-biotin and avidin-biotin maleimide noncovalent complexes have been observed by electrospray ionization mass spectrometry (ESI-MS) by using an extended mass range quadrupole mass spectrometer. By utilizing mild ESI interface conditions,
Autor:
Karen J. Light-Wahl, Richard D. Smith
Publikováno v:
Biological Mass Spectrometry. 22:493-501
Autor:
Chuen-Shang C. Wu, Richard D. Smith, Charles G. Edmonds, Joseph A. Loo, Karen J. Light-Wahl, H. Ewa Witkowska, Cedric H.L. Shackleton
Publikováno v:
Biological Mass Spectrometry. 22:112-120
Electrospray ionization collisionally activated dissociation (CAD) mass spectra of multiply charged human hemoglobin beta-chain variant proteins (146 amino acid residues, 15.9 kDa), generated in the atmospheric pressure/vacuum interface and in the co
Publikováno v:
Journal of the American Society for Mass Spectrometry. 3:624-630
Investigations of gas-phase proton transfer reactions have been performed on protein molecular ions generated by electrospray ionization (ESI). Their reactions were studied in a heated capillary inlet/reactor prior to expansion into a quadrupole mass
Publikováno v:
Organic Mass Spectrometry. 27:811-821
The ‘softness’ of the electrospray ionization (ESI) method provides a direct link between solution chemistry and the inherent gas-phase environment of mass Spectrometry. Available results related to the preservation of non-covalent associations i
Publikováno v:
Journal of toxicology and environmental health. 40(2-3)
In this article, we briefly highlight the use of capillary electrophoresis for sampling, manipulating, and separating extremely small sample sizes. The extraordinary sensitivity that can be obtained by combined capillary electrophoresis-mass spectrom
Publikováno v:
Journal of the American Chemical Society. 116:6027-6028
We have observed by ESI-MS the noncovalent complex formed between a minor groove binding molecule and a 12 base pair self-complementary oligonucleotide. When the ratio of Distamycin Dm to oligonucleotide was varied, oligonucleotide duplex, 1:1 Dm/oli
Publikováno v:
Journal of the American Chemical Society. 115:5869-5870
In this communication, we report the successful ionization and dethection of the dimeric and tetrameric forms of concanavalin A (Con A) by ESI/MS. Concanavalin A, the jack bean lectin, has been the subject of many biochemical studies. Results show th