Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Karen J. Knox"'
In vivo tumour imaging employing regional delivery of novel gallium radiolabelled polymer composites
Autor:
Ross W. Stephens, Gregory D. Tredwell, Jessica L. Bell, Karen J. Knox, Lee A. Philip, Tim J. Senden, Michael J. Tapner, Stephanie A. Bickley, Marcel R. Tanudji, Stephen K. Jones
Publikováno v:
Biomaterials Research, Vol 25, Iss 1, Pp 1-9 (2021)
Abstract Background Understanding the regional vascular delivery of particles to tumour sites is a prerequisite for developing new diagnostic and therapeutic composites for treatment of oncology patients. We describe a novel imageable 67Ga-radiolabel
Externí odkaz:
https://doaj.org/article/6604bce6ff884428b4aa04740f8ffd1a
Autor:
Lee Andrew Philip, Gregory David Tredwell, Kelly M. Debono, Ross W. Stephens, Michael J. Tapner, Marcel R. Tanudji, Stephanie A. Bickley, Jessica L. Bell, Karen J. Knox, Timothy Senden, Stephen K. Jones, Jillean G. Winter, David Wallace King
Publikováno v:
International Journal of Nanomedicine. 14:889-900
Purpose Selective internal radiation therapy (SIRT) is an effective treatment option for liver tumors, using Y-90-loaded polymer microspheres that are delivered via catheterization of the hepatic artery. Since Y-90 is a beta emitter and not convenien
In vivo tumour imaging employing regional delivery of novel gallium radiolabelled polymer composites
Autor:
Jessica L. Bell, Marcel R. Tanudji, Stephen K. Jones, Michael J. Tapner, Gregory David Tredwell, Ross W. Stephens, Karen J. Knox, Lee Andrew Philip, Stephanie A. Bickley, Timothy Senden
Publikováno v:
Biomaterials Research
Biomaterials Research, Vol 25, Iss 1, Pp 1-9 (2021)
Biomaterials Research, Vol 25, Iss 1, Pp 1-9 (2021)
Background Understanding the regional vascular delivery of particles to tumour sites is a prerequisite for developing new diagnostic and therapeutic composites for treatment of oncology patients. We describe a novel imageable 67Ga-radiolabelled polym
Publikováno v:
Biomaterials. 34:1732-1738
Diagnostic imaging of the blood perfusion of the lungs is currently performed using particles of macro-aggregated albumin, which are mechanically arrested at limiting diameters of the capillary bed. While the proportion of blood flow obstructed is ty
Autor:
Ross W. Stephens, Jessica L. Bell, Marcel R. Tanudji, Stephen K. Jones, Timothy Senden, Jian H. Pang, Karen J. Knox, Jillean G. Winter, David Wallace King, Lee Andrew Philip, Christopher R. Parish, Michael J. Tapner, Kelly M. Debono, Stephanie A. Bickley
Publikováno v:
Biomaterials. 39
Delivery of chemotherapeutic drugs to tumours by reformulation as nanoparticles has often been proposed as a means of facilitating increased selective uptake, exploiting the increased permeability of the tumour vasculature. However realisation of thi
Autor:
Jessica L. Blackmore, David Wallace King, Karen J. Knox, Timothy Senden, Ross W. Stephens, Craig Freeman, Sergei Lobov, Christopher R. Parish
Publikováno v:
Biomaterials. 34(22)
Recent findings on the role of circulating histone proteins in mediating acute lung injury prompted us to investigate whether there is a specific mechanism for accumulation of histones in the lungs. Binding sites for polycations are already known in