Zobrazeno 1 - 10
of 48
pro vyhledávání: '"Karen J. Colley"'
Publikováno v:
Encyclopedia of Biological Chemistry III ISBN: 9780128220405
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::58af7c9b2e92c996513a75b93f156520
https://doi.org/10.1016/b978-0-12-819460-7.00255-3
https://doi.org/10.1016/b978-0-12-819460-7.00255-3
Autor:
Helena L. Palka-Hamblin, Karen J. Colley, Hao Jui Hsu, Michael Cheong, Seungpyo Hong, Gaurang P. Bhide, Ja Hye Myung
Publikováno v:
Analytical Chemistry. 90:3670-3675
Enumeration of circulating tumor cells (CTCs) of small-cell lung cancer (SCLC) patients has been shown to predict the disease progress and long-term survival. Most CTC detection methods rely on epithelial surface markers, such as epithelial cell adhe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c2cb29659be28d0c5214d543dafc135
https://doi.org/10.1021/acs.analchem.8b00427
https://doi.org/10.1021/acs.analchem.8b00427
Publikováno v:
Journal of Biological Chemistry. 293:701-716
Polysialic acid (polySia) is a large glycan polymer that is added to some glycoproteins by two polysialyltransferases (polySTs), ST8Sia-II and ST8Sia-IV. As polySia modulates cell adhesion and signaling, immune cell function, and tumor metastasis, it
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::616561f3d7a32103a974715fa226eaee
https://doi.org/10.1074/jbc.ra117.000401
https://doi.org/10.1074/jbc.ra117.000401
Autor:
Karen J. Colley, Gaurang P. Bhide
Publikováno v:
Histochemistry and Cell Biology
Sialylated N-glycans play essential roles in the immune system, pathogen recognition and cancer. This review approaches the sialylation of N-glycans from three perspectives. The first section focuses on the sialyltransferases that add sialic acid to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb57f69e94d3941971a90bfbd91d5bce
http://europepmc.org/articles/PMC7088086
http://europepmc.org/articles/PMC7088086
Polysialic acid (polySia) is a unique post-translational modification found on a small set of mammalian glycoproteins. Composed of long chains of α2,8-linked sialic acid, this large, negatively charged polymer attenuates protein and cell adhesion an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b44adc8ec4471301f9ff3a6bc4fafbb4
https://europepmc.org/articles/PMC5577389/
https://europepmc.org/articles/PMC5577389/
Publikováno v:
Critical Reviews in Biochemistry and Molecular Biology. 49:498-532
As an anti-adhesive, a reservoir for key biological molecules, and a modulator of signaling, polysialic acid (polySia) is critical for nervous system development and maintenance, promotes cancer metastasis, tissue regeneration and repair, and is impl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61e0ea4d397addcec568e3f31904c0f5
https://doi.org/10.3109/10409238.2014.976606
https://doi.org/10.3109/10409238.2014.976606
Publikováno v:
Journal of Biological Chemistry. 288:7282-7293
The neural cell adhesion molecule (NCAM) is the major substrate for the polysialyltransferases (polySTs), ST8SiaII/STX and ST8SiaIV/PST. The polysialylation of NCAM N-glycans decreases cell adhesion and alters signaling. Previous work demonstrated th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64f5c2391427045c92775af17a59fe29
https://doi.org/10.1074/jbc.m112.438374
https://doi.org/10.1074/jbc.m112.438374
Sequence Requirements for Neuropilin-2 Recognition by ST8SiaIV and Polysialylation of Its O-Glycans*
Polysialic acid is an oncofetal glycopolymer, added to the glycans of a small group of substrates, that controls cell adhesion and signaling. One of these substrates, neuropilin-2, is a VEGF and semaphorin co-receptor that is polysialylated on its O-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ad863f4609df076c9d96b6214a1f5b7
https://europepmc.org/articles/PMC4850285/
https://europepmc.org/articles/PMC4850285/
Publikováno v:
Journal of Biological Chemistry. 286:4525-4534
Polysialic acid is an anti-adhesive glycan that modifies a select group of mammalian proteins. The primary substrate of the polysialyltransferases (polySTs) is the neural cell adhesion molecule (NCAM). Polysialic acid negatively regulates cell adhesi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86ae9c23f0cdd9bccc210a0953746c50
https://doi.org/10.1074/jbc.m110.200386
https://doi.org/10.1074/jbc.m110.200386
Autor:
Matthew G. Thompson, Kristin G. Swartzentruber, Deirdre A. Foley, Karen J. Colley, Shalu Shiv Mendiratta
Publikováno v:
Journal of Biological Chemistry. 285:35056-35067
Polysialic acid is a developmentally regulated, anti-adhesive polymer that is added to N-glycans on the fifth immunoglobulin domain (Ig5) of the neural cell adhesion molecule (NCAM). We found that the first fibronectin type III repeat (FN1) of NCAM i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::96d7163125082ace2aa2a400124bc71b
https://doi.org/10.1074/jbc.m110.170209
https://doi.org/10.1074/jbc.m110.170209