Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Karen J Kieser"'
Autor:
Catherine Baranowski, Michael A Welsh, Lok-To Sham, Haig A Eskandarian, Hoong Chuin Lim, Karen J Kieser, Jeffrey C Wagner, John D McKinney, Georg E Fantner, Thomas R Ioerger, Suzanne Walker, Thomas G Bernhardt, Eric J Rubin, E Hesper Rego
Publikováno v:
eLife, Vol 7 (2018)
In most well-studied rod-shaped bacteria, peptidoglycan is primarily crosslinked by penicillin-binding proteins (PBPs). However, in mycobacteria, crosslinks formed by L,D-transpeptidases (LDTs) are highly abundant. To elucidate the role of these unus
Externí odkaz:
https://doaj.org/article/6695fdf7fa9f4cceb2741307353a71cf
Autor:
Karen J Kieser, Cara C Boutte, Jemila C Kester, Christina E Baer, Amy K Barczak, Xavier Meniche, Michael C Chao, E Hesper Rego, Christopher M Sassetti, Sarah M Fortune, Eric J Rubin
Publikováno v:
PLoS Pathogens, Vol 11, Iss 6, p e1005010 (2015)
Cell growth and division are required for the progression of bacterial infections. Most rod-shaped bacteria grow by inserting new cell wall along their mid-section. However, mycobacteria, including the human pathogen Mycobacterium tuberculosis, produ
Externí odkaz:
https://doaj.org/article/765fe55a1c6d4311bb94f15f6f51c4b4
Autor:
Michael C Chao, Karen J Kieser, Shoko Minami, Daniela Mavrici, Bree B Aldridge, Sarah M Fortune, Tom Alber, Eric J Rubin
Publikováno v:
PLoS Pathogens, Vol 9, Iss 2, p e1003197 (2013)
Peptidoglycan hydrolases are a double-edged sword. They are required for normal cell division, but when dysregulated can become autolysins lethal to bacteria. How bacteria ensure that peptidoglycan hydrolases function only in the correct spatial and
Externí odkaz:
https://doaj.org/article/30ff609cce2e49018fc57f5688d1a709
Autor:
Landys Lopez Quezada, Alexa P. Harnagel, Sae Woong Park, Julien Vaubourgeix, Julia Roberts, Carl Nathan, Catherine Baranowski, Sabine Ehrt, Karen J. Kieser, Brock Nelson, Allison Fay, Eric Rubin, Amy Yang, Tania J. Lupoli, Xiuju Jiang
Publikováno v:
Mol Microbiol
Bacterial chaperones ClpB and DnaK, homologs of the respective eukaryotic heat shock proteins Hsp104 and Hsp70, are essential in the reactivation of toxic protein aggregates that occur during translation or periods of stress. In the pathogen Mycobact
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec3a0bf69c0aa6f427c60648e34ac242
https://europepmc.org/articles/PMC9007595/
https://europepmc.org/articles/PMC9007595/
Autor:
Eric J. Rubin, Chi Hao Luan, Karen J. Kieser, Zdzislaw Wawrzak, Ekaterina V. Filippova, Olga Kiryukhina, Wayne F. Anderson
Publikováno v:
The Febs Journal
UNLABELLED Mycobacterium tuberculosis is a human respiratory pathogen that causes the deadly disease tuberculosis. The rapid global spread of antibiotic-resistant M. tuberculosis makes tuberculosis infections difficult to treat. To overcome this prob
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::010f185841a593c7c776a80910f1cf65
http://europepmc.org/articles/PMC5245116
http://europepmc.org/articles/PMC5245116
Autor:
Thomas G. Bernhardt, Catherine Baranowski, Karen J. Kieser, Thomas R. Ioerger, Michael Welsh, Haig A. Eskandarian, E. Hesper Rego, Jeffrey C Wagner, Hoong Chuin Lim, Lok-To Sham, John D. McKinney, Eric J. Rubin, Suzanne Walker, Georg E. Fantner
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::52e51a3d17143205f297543fce61a455
https://doi.org/10.7554/elife.37516.042
https://doi.org/10.7554/elife.37516.042
Autor:
Catherine, Baranowski, Michael A, Welsh, Lok-To, Sham, Haig A, Eskandarian, Hoong Chuin, Lim, Karen J, Kieser, Jeffrey C, Wagner, John D, McKinney, Georg E, Fantner, Thomas R, Ioerger, Suzanne, Walker, Thomas G, Bernhardt, Eric J, Rubin, E Hesper, Rego
Publikováno v:
eLife
In most well-studied rod-shaped bacteria, peptidoglycan is primarily crosslinked by penicillin-binding proteins (PBPs). However, in mycobacteria, crosslinks formed by L,D-transpeptidases (LDTs) are highly abundant. To elucidate the role of these unus
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::bfd26830cb325bef14377511b90a9500
https://pubmed.ncbi.nlm.nih.gov/30355443
https://pubmed.ncbi.nlm.nih.gov/30355443
Autor:
Welsh Ma, Thomas R. Ioerger, Catherine Baranowski, Karen J. Kieser, Thomas G. Bernhardt, Hoong Chuin Lim, Lok-To Sham, John D. McKinney, Haig A. Eskandarian, Eric J. Rubin, Rego Eh, Suzanne Walker, Georg E. Fantner, Jeffrey C Wagner
In most well studied rod-shaped bacteria, peptidoglycan is primarily crosslinked by penicillin binding proteins (PBPs). However, in mycobacteria, L,D-transpeptidase (LDT)-mediated crosslinks are highly abundant. To elucidate the role of these unusual
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cff79ebea4b4a603f6f7d48da47f59bb
https://doi.org/10.1101/291823
https://doi.org/10.1101/291823
Autor:
Jonathan C. Kagan, Karen J. Kieser
The receptors of the innate immune system detect specific microbial ligands to promote effective inflammatory and adaptive immune responses. Although this idea is well appreciated, studies in recent years have highlighted the complexity of innate imm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::caf800a8712aa3cfc8bb75604c8f2423
https://europepmc.org/articles/PMC6698371/
https://europepmc.org/articles/PMC6698371/
Autor:
Sebastien Gagneux, Bruce W. Birren, Bhavana Muddukrishna, Robin M. Warren, Jennifer L. Gardy, B. Jesse Shapiro, Eric J. Rubin, Devinder Kaur, Midori Kato-Maeda, Megan Murray, Jamie E. Posey, Natalia Kurepina, Maha R. Farhat, Alistair Calver, Pardis C. Sabeti, Patrick Tang, Bonnie B. Plikaytis, Eric S. Lander, Alexander Sloutsky, Razvan Sultana, Mark L. Borowsky, Elizabeth M. Streicher, Thomas C. Victor, Karen R. Jacobson, Mabel Rodrigues, James C. Johnston, Karen J. Kieser, James E. Galagan, Barry N. Kreiswirth, Marco R. Oggioni
Publikováno v:
Nature genetics
PMC
PMC
M. tuberculosis is evolving antibiotic resistance, threatening attempts at tuberculosis epidemic control. Mechanisms of resistance, including genetic changes favored by selection in resistant isolates, are incompletely understood. Using 116 newly seq
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83d5e35bf9f9ea754f834c6c4aef038f
http://europepmc.org/articles/PMC3887553
http://europepmc.org/articles/PMC3887553