Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Karen I. Fritz"'
Autor:
Anayansi Lasso Pirot, Om P. Mishra, Karen I. Fritz, Maria Delivoria-Papadopoulos, Qazi M. Ashraf
Publikováno v:
Neonatology. 91:20-27
Background: Hypocapnia occurs in the newborn infant inadvertently or as a therapeutic modality and may result in neuronal and mitochondrial alterations in the newborn brain. Since mitochondria regulate apoptosis, these alterations may initiate a casc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d101cad2b4daa05d1a442ae6c7e24fd8
https://doi.org/10.1159/000096967
https://doi.org/10.1159/000096967
Autor:
Agustin Legido, Maria Delivoria-Papadopoulos, Karen I. Fritz, Om P. Mishra, Christos D. Katsetos, Nehal A. Parikh
Publikováno v:
Neurochemical Research. 31:899-906
Cerebral hypoxia results in generation of nitric oxide (NO) free radicals by Ca++-dependent activation of neuronal nitric oxide synthase (nNOS). The present study tests the hypothesis that the hypoxia-induced increased expression of nNOS in cortical
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fbeebf1120f491cd5b7450f2ea40e2af
https://doi.org/10.1007/s11064-006-9094-y
https://doi.org/10.1007/s11064-006-9094-y
Autor:
Om P. Mishra, Nehal A. Parikh, Syed Hassan Haider, Maria Delivoria Papadopoulos, David F. Sorrentino, Karen I. Fritz
Publikováno v:
Neurochemical Research. 29:455-459
This study tested the hypothesis that cerebral hypoxia results in nitric oxide (NO)-mediated modification of the glycine-binding site of the N-methyl-D-aspartate (NMDA) receptor. Glycine binding characteristics were determined in normoxic, hypoxic, a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43ec1644a782c72cfa7ead38f3300c3f
https://doi.org/10.1023/b:nere.0000013751.17464.ee
https://doi.org/10.1023/b:nere.0000013751.17464.ee
Publikováno v:
Neonatology. 85:128-137
The present study tests the hypothesis that during graded hypoxia, N-methyl-D-aspartate (NMDA) receptor expression and phosphorylation are altered in the cerebral cortex of newborn piglets. Studies were performed in anesthetized, ventilated piglets,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ee925216b5ca058d266d49b873612bae
https://doi.org/10.1159/000074969
https://doi.org/10.1159/000074969
Publikováno v:
Neuroscience Letters. 352:211-215
The present study tests the hypothesis that a PaCO 2 of 27 mmHg for 1 hr results in increased neuronal nuclear Ca ++ /calmodulin-dependent protein kinase IV (CaM kinase IV) activity, pro-apoptotic protein expression and DNA fragmentation in the cereb
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d26e3bd80444d1a58337a5e099dd532
https://doi.org/10.1016/j.neulet.2003.08.049
https://doi.org/10.1016/j.neulet.2003.08.049
Autor:
Om P. Mishra, Qazi M. Ashraf, Alan B. Zubrow, Karen I. Fritz, Juan R. Ballesteros, Maria Delivoria-Papadopoulos
Publikováno v:
Brain Research. 954:60-67
The present study tests the hypothesis that nitric oxide mediates the hypoxia-induced increase in expression of Bax and in DNA fragmentation in the cerebral cortex of newborn piglets, and that administration of N-nitro-L-arginine (NNLA), a nitric oxi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44cb5ab3489e78b75c7ce0e4e867a4fd
https://doi.org/10.1016/s0006-8993(02)03342-5
https://doi.org/10.1016/s0006-8993(02)03342-5
Publikováno v:
Pediatric Research. 50:586-589
Previous studies have shown that severe hypocapnic ventilation [arterial carbon dioxide partial pressure (PaCO(2)) 7-10 mm Hg] in newborn animals results in decreased cerebral blood flow and decreased tissue oxidative metabolism. The present study te
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b01a2b9826f3c9c5a489fe24bc47cc30
https://doi.org/10.1203/00006450-200111000-00009
https://doi.org/10.1203/00006450-200111000-00009
Publikováno v:
Brain Research. 891:266-273
Previous studies have shown that the N -methyl- d -aspartate (NMDA) receptor is modified during hypoxia in the cerebral cortex of newborn piglets. The present study tests the hypothesis that the NMDA receptor 3-(2-carboxypiperazin-4-yl)propyl-1-phosp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7cf82ac0259fae6c9e0d9cf3e87661af
https://doi.org/10.1016/s0006-8993(00)03223-6
https://doi.org/10.1016/s0006-8993(00)03223-6
Publikováno v:
Mental Retardation and Developmental Disabilities Research Reviews. 7:249-253
The NMDA-type glutamate receptor is a predominant mediator of excitotoxicity in the immature brain due to overexpression of the receptor in the developing brain. Within the development period however, the extent of NMDA receptor mediated processes in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce6f08e344b5b52b393f3475065bc93f
https://doi.org/10.1002/mrdd.1034
https://doi.org/10.1002/mrdd.1034
Publikováno v:
Neuroscience. 92:685-692
The present study tests the hypothesis that Mg2+ modification of N-methyl-D-aspartate receptor ion channel opening is altered during hypoxia and correlates with the progressive decrease in cerebral energy metabolism induced by hypoxia. Studies were p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ad63069873b959d070e838eadeeb0f3
https://doi.org/10.1016/s0306-4522(98)00761-1
https://doi.org/10.1016/s0306-4522(98)00761-1