Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Karen Hon"'
Autor:
William Murphy, Sha Liu, Karen Hon, John Finnie, George Spyro Bouras, Sholeh Feizi, Ghais Houtak, Gohar Shaghayegh, Erich Vyskocil, Peter-John Wormald, Sarah Vreugde, Alkis J. Psaltis
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 6, p 3336 (2024)
Chronic rhinosinusitis (CRS) is characterized by sinonasal mucosal inflammation. Staphylococcus aureus (S. aureus) is associated with severe CRS phenotypes. Different animal models have been proposed to study the association of CRS and S. aureus. How
Externí odkaz:
https://doaj.org/article/759d1b6a5ece4cd6842e00b72a631083
Autor:
Shuman Huang, Karen Hon, Catherine Bennett, Hua Hu, Martha Menberu, Peter-John Wormald, Yulin Zhao, Sarah Vreugde, Sha Liu
Publikováno v:
Frontiers in Microbiology, Vol 14 (2023)
Externí odkaz:
https://doaj.org/article/e4249bf76b7449d6ba38cad3f69eb85a
Autor:
Shuman Huang, Karen Hon, Catherine Bennett, Hua Hu, Martha Menberu, Peter-John Wormald, Yulin Zhao, Sarah Vreugde, Sha Liu
Publikováno v:
Frontiers in Microbiology, Vol 13 (2022)
BackgroundCorynebacterium accolens (C. accolens) is a common nasal colonizer, whereas Staphylococcus aureus (S. aureus) is typically regarded a pathogenic organism in patients with chronic rhinosinusitis (CRS). This study aims to evaluate the interac
Externí odkaz:
https://doaj.org/article/90086cc18a774703ab179822e615e622
Autor:
Mahnaz Ramezanpour, Harrison Bolt, Karen Hon, Gohar Shaghayegh, Hadi Rastin, Kevin Aaron Fenix, James Psaltis Alkis, Peter-John Wormald, Sarah Vreugde
Publikováno v:
Biology Open, Vol 11, Iss 8 (2022)
Patient-derived organoids grown in three-dimensional cultures provide an excellent platform for phenotypic high-throughput screening and drug-response research. Organoid technology has been applied to study stem cell biology and various human patholo
Externí odkaz:
https://doaj.org/article/6e9aa9e57c034097b98765e092a7c1a4
Autor:
Sha Liu, Karen Hon, George Spyro Bouras, Alkis James Psaltis, Keith Shearwin, Peter-John Wormald, Sarah Vreugde
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 11, p 6116 (2022)
The high infection and mortality rate of methicillin-resistant Staphylococcus aureus (MRSA) necessitates the urgent development of new treatment strategies. Bacteriophages (phages) have several advantages compared to antibiotics for the treatment of
Externí odkaz:
https://doaj.org/article/926738f5c3e649cd840448cd1919d17e
Autor:
Karen Hon, Sha Liu, Sophie Camens, George Spyro Bouras, Alkis James Psaltis, Peter-John Wormald, Sarah Vreugde
Publikováno v:
Microorganisms, Vol 10, Iss 1, p 102 (2022)
Escherichia coli (E. coli) are common bacteria that colonize the human and animal gastrointestinal tract, where they help maintain a balanced microbiome. However, some E. coli strains are pathogenic and can cause serious infectious diseases and life-
Externí odkaz:
https://doaj.org/article/5825d16fc15b4a0182310a3b6cf1b1c3
Autor:
Sophie Camens, Sha Liu, Karen Hon, George Spyro Bouras, Alkis James Psaltis, Peter-John Wormald, Sarah Vreugde
Publikováno v:
Microorganisms, Vol 9, Iss 9, p 2001 (2021)
A Pseudomonas aeruginosa (P. aeruginosa) airway infection is one of the predominant causes contributing to the high morbidity and mortality rates in cystic fibrosis (CF) patients. The emergence of antibiotic resistant P. aeruginosa strains has led to
Externí odkaz:
https://doaj.org/article/648031df47304f7e8de2c2cb3a0fe2f4
Cytokine-Induced Modulation of SARS-CoV2 Receptor Expression in Primary Human Nasal Epithelial Cells
Autor:
Mahnaz Ramezanpour, Harrison Bolt, Karen Hon, George Spyro Bouras, Alkis James Psaltis, Peter-John Wormald, Sarah Vreugde
Publikováno v:
Pathogens, Vol 10, Iss 7, p 848 (2021)
Background: Viral entry of severe acute respiratory syndrome coronavirus 2 (SARS-CoV2) via the spike protein enables endocytosis into host cells using the ACE2 receptor and TMPRSS2. The frequent upper respiratory tract symptoms of COVID-19 and the lo
Externí odkaz:
https://doaj.org/article/b57e4c4c906b485a964b9e5c75182942
Publikováno v:
Inflammation Research. 72:251-262
Objective and design Staphylococcus aureus (S. aureus) is one of the leading causes of human respiratory tract infections. The function of Staphylococcal protein A (SpA), expressed on the S. aureus bacterial membrane and released in the environment,
Autor:
Jin-Ai Mary Anne Tan, Kek Heng Chua, Suat Moi Puah, Ping Chin Lee, Savithri D. Puthucheary, Fui‐Fui Ching, Ching‐Kee Karen Hon, Tien-Tien Vicky Lau
Publikováno v:
Aquaculture Research. 51:3972-3982