Breastfeeding, Cellular Immune Activation, and Myocardial Recovery in Peripartum Cardiomyopathy

Autor: Agnes Koczo, MD, Amy Marino, MD, Arun Jeyabalan, MD, Uri Elkayam, MD, Leslie T. Cooper, MD, James Fett, MD, MPH, Joan Briller, MD, Eileen Hsich, MD, Lori Blauwet, MD, Charles McTiernan, PhD, Penelope A. Morel, MD, Karen Hanley-Yanez, BS, Dennis M. McNamara, MD, MS, Dennis M McNamara, MD, James D. Fett, MD, Jessica Pisarcik, RN, BSN, John Gorcsan, III, MD, Erik Schelbert, MD, Rami Alharethi, MD, Kismet Rasmusson, CRNP, Kim Brunisholz, Amy Butler, BS, CCRP, Deborah Budge, A.G. Kfoury, MD, Benjamin Horne, PhD, Joe Tuinei, Heather Brown, Julie Damp, MD, Allen J. Naftilan, MD, Jill Russell, RN, MSN, Darla Freehardt, LPN, BS, CCRP, Cynthia Oblak, CCRC, Greg Ewald, MD, Donna Whitehead, RN, Jean Flanagan, RN, Anne Platts, Jorge Caro, MPH, Stephanie Mullin, RN, Michael M. Givertz, MD, M. Susan Anello, RN, BS, Navin Rajagopalan, MD, David Booth, MD, Tiffany Sandlin, RN, Wendy Wijesiri, RN, Lori A. Blauwet, MD, Joann Brunner, RN, Mary Phelps, Ruth Kempf, Kalgi Modi, MD, Tracy Norwood, Decebal Sorin Griza, MD, G. Michael Felker, MD, Robb Kociol, MD, Patricia Adams, RN, Gretchen Wells, MD, Vinay Thohan, MD, Deborah Wesley-Farrington, RN, BSN, CCRC, CCA, Sandra Soots, RN, CCRC, Richard Sheppard, MD, Caroline Michel, MD, Nathalie Lapointe, RN, PhD, Heather Nathaniel, Angela Kealey, MD, Marc Semigran, MD, Maureen Daher, RN, John Boehmer, MD, David Silber, MD, Eric Popjes, MD, Patricia Frey, RN, Todd Nicklas, RN, Jeffrey Alexis, MD, Lori Caufield, RN, BSN, CCRC, John W. Thornton, III, MD, Mindy Gentry, MD, Vincent J.B. Robinson, MBBS, Gyanendra K. Sharma, MD, Joan Holloway, BS, Maria Powell, LPN, CCRC, David Markham, MD, Mark Drazner, MD, Lynn Fernandez, RN, Mark Zucker, MD, David A. Baran, MD, Martin L. Gimovsky, MD, Natalia Hochbaum, MD, Bharati Patel, RN, CCRC, Laura Adams, RN, BSN, Gautam Ramani, MD, Stephen Gottlieb, MD, Shawn Robinson, MD, Stacy Fisher, MD, Joanne Marshall, BSN, MS, Jennifer Haythe, MD, Donna Mancini, MD, Rachel Bijou, MD, Maryjane Farr, MD, Marybeth Marks, Henry Arango, Biykem Bozkurt, MD, PhD, FACC, FAHA, Mariana Bolos, Paul Mather, MD, Sharon Rubin, MD, Raphael Bonita, MD, Susan Eberwine, RN, Hal Skopicki, MD, PhD, Kathleen Stergiopoulos, MD, Ellen McCathy-Santoro, MD, Jennifer Intravaia, RN, CCRCII, Elizabeth Maas, Jordan Safirstein, MD, Audrey Kleet, RN, MS, ACNP-BC, CCRN, CCTC, Nancy Martinez, RN, Christine Corpoin, RN, Donna Hesari, RN, Sandra Chaparro, MD, Laura J. Hudson, MA, MPH, CCRC, Jalal K. Ghali, MD, Zora Injic, RN, BSc, MSA, Ilan S. Wittstein, MD

Publikováno v: JACC: Basic to Translational Science, Vol 4, Iss 3, Pp 291-300 (2019)

Summary: The etiology of peripartum cardiomyopathy remains unknown. One hypothesis is that an increase in the 16-kDa form of prolactin is pathogenic and suggests that breastfeeding may worsen peripartum cardiomyopathy by increasing prolactin, while b

Externí odkaz: https://doaj.org/article/6b537dab273b427cb490b11cb95baf93

Adrenergic Polymorphisms and Survival in African Americans With Heart Failure: Results From A-HeFT

Autor: Dennis M. McNamara, Arthur M. Feldman, Karen Hanley-Yanez, Amber E. Johnson, Clyde W. Yancy, Anne L. Taylor

Publikováno v: J Card Fail

BACKGROUND: Polymorphisms in adrenergic signaling affect the molecular function of adrenergic receptors and related proteins. The β1 adrenergic receptor (ADRB1) Arg389Gly, G-protein receptor kinase type 5 (GRK5) Gln41Leu, G-protein β-3 subunit (GNB

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99d14d47544ca87a13b3e28b056a3f14
https://doi.org/10.1016/j.cardfail.2019.04.007

ACTIVIN A AND POSTPARTUM HYPERTENSION IN PERIPARTUM CARDIOMYOPATHY

Autor: Agnes Koczo, Amy Marino, Karen Hanley-Yanez, Dennis M. McNamara

Publikováno v: Journal of the American College of Cardiology. 79:1966

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::88512cf05b3f8a5cea6d736203ab3eed
https://doi.org/10.1016/s0735-1097(22)02957-6

Myocardial Recovery in Patients With Systolic Heart Failure and Autoantibodies Against β 1 -Adrenergic Receptors

Autor: Yuji Nagatomo, Dennis M. McNamara, Jeffrey D. Alexis, Leslie T. Cooper, G. William Dec, Daniel F. Pauly, Richard Sheppard, Randall C. Starling, W.H. Wilson Tang, Karen Janosko, Charles McTiernan, Barry London, Karen Hanley-Yanez, John Gorcsan, Hidekazu Tanaka, Mathew Suffoletto, Cynthia Oblak, Annette McNallan, LuAnne Koenig, Paul Mather, Natalie Pierson, Sharon Rubin, Yanique Bell, Alicia Ervin, John Boehmer, Patricia Frey, Jeffrey Alexis, Janice Schrack, Pam LaDuke, Guillermo Torre-Amione, Jeannie Arredondo, Pamela C. Smith, Stephanie Fuoco, Ilan S. Wittstein, Elayne Breton, Vinay Thohan, Deborah Wesley, Diane Cocca-Spofford, David W. Markham, Lynn Fernandez, Colleen Debes, Mark J. Zucker, Laura Adams, Peter Liu, Judith Renton, Jagat Narula, Byron Allen, Elizabeth Westberg

Publikováno v: Journal of the American College of Cardiology. 69:968-977

Background Among various cardiac autoantibodies (AAbs), those recognizing the β 1 -adrenergic receptor (β 1 AR) demonstrate agonist-like effects and induce myocardial damage that can be reversed by β-blockers and immunoglobulin G3 (IgG3) immunoads

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c96e5f783e621015657fb8888963dc91
https://doi.org/10.1016/j.jacc.2016.11.067

Circulating T-Cell Subsets, Monocytes, and Natural Killer Cells in Peripartum Cardiomyopathy: Results From the Multicenter IPAC Study

Autor: Charles F. McTiernan, Penelope Morel, Leslie T. Cooper, Navin Rajagopalan, Vinay Thohan, Mark Zucker, John Boehmer, Biykem Bozkurt, Paul Mather, John Thornton, Jalal K. Ghali, Karen Hanley-Yanez, James Fett, Indrani Halder, Dennis M. McNamara, James D. Fett, Jessica Pisarcik, Charles McTiernan, John Gorcsan, Erik Schelbert, Rami Alharethi, Kismet Rasmusson, Kim Brunisholz, Amy Butler, Deborah Budge, A.G. Kfoury, Benjamin Horne, Joe Tuinei, Heather Brown, Julie Damp, Allen J. Naftilan, Jill Russell, Darla Freehardt, Eileen Hsich, Cynthia Oblak, Greg Ewald, Donna Whitehead, Jean Flanagan, Anne Platts, Uri Elkayam, Jorge Caro, Stephanie Mullin, Michael M. Givertz, M. Susan Anello, David Booth, Tiffany Sandlin, Wendy Wijesiri, Lori A. Blauwet, Joann Brunner, Mary Phelps, Ruth Kempf, Kalgi Modi, Tracy Norwood, Joan Briller, Decebal Sorin Griza, G. Michael Felker, Robb Kociol, Patricia Adams, Gretchen Wells, Deborah Wesley-Farrington, Sandra Soots, Richard Sheppard, Caroline Michel, Nathalie Lapointe, Heather Nathaniel, Angela Kealey, Marc Semigran, Maureen Daher, David Silber, Eric Popjes, Patricia Frey, Todd Nicklas, Jeffrey Alexis, Lori Caufield, John W. Thornton, Mindy Gentry, Vincent J.B. Robinson, Gyanendra K. Sharma, Joan Holloway, Maria Powell, David Markham, Mark Drazner, Lynn Fernandez, David A. Baran, Martin L. Gimovsky, Natalia Hochbaum, Bharati Patel, Laura Adams, Gautam Ramani, Stephen Gottlieb, Shawn Robinson, Stacy Fisher, Joanne Marshall, Jennifer Haythe, Donna Mancini, Rachel Bijou, Maryjane Farr, Marybeth Marks, Henry Arango, Mariana Bolos, Sharon Rubin, Raphael Bonita, Susan Eberwine, Hal Skopicki, Kathleen Stergiopoulos, Ellen McCathy-Santoro, Jennifer Intravaia, Elizabeth Maas, Jordan Safirstein, Audrey Kleet, Nancy Martinez, Christine Corpoin, Donna Hesari, Sandra Chaparro, Laura J. Hudson, Zora Injic, Ilan S. Wittstein

Publikováno v: Journal of cardiac failure. 24(1)

OBJECTIVE: The aim of this work was to evaluate the hypothesis that the distribution of circulating immune cell subsets, or their activation state, is significantly different between peripartum cardiomyopathy (PPCM) and healthy postpartum (HP) women.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cefbc444a197e0bebc8e3d74a6ec7cc0
https://pubmed.ncbi.nlm.nih.gov/29079307