Zobrazeno 1 - 10
of 723
pro vyhledávání: '"Karen H. Lu"'
Autor:
Emily MacArthur, Kara Long Roche, Joseph Sakran, Sunil H. Patel, Peter Najjar, Karen H. Lu, Megan Gornet, Anja S. Frost, Meghan Walrath, Tom Bauer, Gyyoung Oh, Rebecca Stone
Publikováno v:
Gynecologic Oncology Reports, Vol 53, Iss , Pp 101368- (2024)
Given the unremitting obstacles to effectively screen for and treat ovarian cancer (OC), prevention is a necessary countermeasure. The recent discovery of the fallopian tube as the origin of the most common and deadly type of OC, high grade serous ca
Externí odkaz:
https://doaj.org/article/9b16824e591a486fa3f8fe9786bcfc48
Autor:
Carol J. Nowlen, Molly Daniels, Burak Uzunparmak, Ecaterina E. Ileana Dumbrava, Ying Yuan, Keyur P. Patel, Nadine Rayes, Jacqueline Harkenrider, Chetna Wathoo, Jennifer Veazie, Krystle A. Luna, Wanlin Wang, Chacha Horombe, Milind Javle, Jordi Rodon Ahnert, Timothy A. Yap, Banu Arun, Karen H. Lu, Funda Meric-Bernstam
Publikováno v:
Journal of Immunotherapy and Precision Oncology, Vol 7, Iss 1, Pp 7-17 (2024)
Introduction Genomic profiling is performed in patients with advanced or metastatic cancer, in order to direct cancer treatment, often sequencing tumor-only, without a matched germline comparator. However, because many of the genes analyzed on tumor
Externí odkaz:
https://doaj.org/article/1c82c80e6fbe4a119579d33a7fda0372
Autor:
Li Zhang, Chi-Lam Au-Yeung, Chunxian Huang, Tsz-Lun Yeung, Sammy Ferri-Borgogno, Barrett C. Lawson, Suet-Ying Kwan, Zheng Yin, Stephen T. Wong, Vienna Thomas, Karen H. Lu, Kay-Pong Yip, James S. K. Sham, Samuel C. Mok
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 41, Iss 1, Pp 1-20 (2022)
Abstract Background Uterine serous cancer (USC) is the most common non-endometrioid subtype of uterine cancer, and is also the most aggressive. Most patients will die of progressively chemotherapy-resistant disease, and the development of new therapi
Externí odkaz:
https://doaj.org/article/69afaa0e3959490e871f6737d58da8cb
Autor:
Jhalak Dholakia, Yeon Woo Lee, Karen H. Lu, Warner K. Huh, S. Diane Yamada, Katherine C. Fuh, Amanika S. Kumar, Margaret I. Liang, Navya Nair, Kenneth H. Kim
Publikováno v:
Gynecologic Oncology Reports, Vol 44, Iss , Pp 101097- (2022)
Background: Anti-Asian violence increased during the COVID-19 pandemic. Asian American/Pacific Islanders (AAPI) represent a diverse population experiencing a long history of stereotyping and exclusionism; however, this group is often left out of dive
Externí odkaz:
https://doaj.org/article/0ad8758acbed45c2b27fe9ce908668d7
Publikováno v:
Communications Medicine, Vol 1, Iss 1, Pp 1-3 (2021)
Bast et al. discuss the early detection of ovarian cancer in the context of the recent UKCTOCS screening trial. The authors suggest potential reasons why the trial failed to achieve a reduction in mortality and outline next steps in the development o
Externí odkaz:
https://doaj.org/article/6ee4dc197ad9433ca667e5eb53292f86
Autor:
Chi-Lam Au-Yeung, Tsz-Lun Yeung, Abhinav Achreja, Hongyun Zhao, Kay-Pong Yip, Suet-Ying Kwan, Michaela Onstad, Jianting Sheng, Ying Zhu, Dodge L. Baluya, Ngai-Na Co, Angela Rynne-Vidal, Rosemarie Schmandt, Matthew L. Anderson, Karen H. Lu, Stephen T. C. Wong, Deepak Nagrath, Samuel C. Mok
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-16 (2020)
Advanced ovarian cancer usually spreads to the omentum. Here, the authors show that circulating intelectin-1 (ITLN1) has prognostic significance in patients with advanced ovarian cancer, and that mesothelial cell-derived ITLN1 in the omental tumor mi
Externí odkaz:
https://doaj.org/article/a6dd5cbe55934dbcaae176ed33be66a7
Autor:
Adriana M. Coletta, Susan K. Peterson, Leticia A. Gatus, Kate J. Krause, Susan M. Schembre, Susan C. Gilchrist, Banu Arun, Y. Nancy You, Miguel A. Rodriguez-Bigas, Larkin L. Strong, Karen H. Lu, Karen Basen-Engquist
Publikováno v:
Hereditary Cancer in Clinical Practice, Vol 18, Iss 1, Pp 1-24 (2020)
Abstract Introduction Women with pathogenic germline gene variants in BRCA1 and/or BRCA2 are at increased risk of developing ovarian and breast cancer. While surgical and pharmacological approaches are effective for risk-reduction, it is unknown whet
Externí odkaz:
https://doaj.org/article/9f619c1be92c4cad9441c4a5b82e9db4
Autor:
Nadine Rayes, Deborah J. Bowen, Tara Coffin, Denise Nebgen, Christine Peterson, Mark F. Munsell, Kathleen Gavin, Rebecca Lechner, Jamie Crase, Deborah Polinsky, Iris Romero, Stephanie V. Blank, Douglas A. Levine, Barbara M. Norquist, Elizabeth M. Swisher, Karen H. Lu
Publikováno v:
BMC Cancer, Vol 19, Iss 1, Pp 1-8 (2019)
Abstract Background Studies have consistently indicated that the majority of individuals meeting the US Prevention Services Task Force guidelines for genetic testing have not had genetic counseling or testing. Despite increased availability and lower
Externí odkaz:
https://doaj.org/article/2de4a07221254aad8fba0ebfef4e44d2
Autor:
R. Tyler Hillman, Joseph Celestino, Christopher Terranova, Hannah C. Beird, Curtis Gumbs, Latasha Little, Tri Nguyen, Rebecca Thornton, Samantha Tippen, Jianhua Zhang, Karen H. Lu, David M. Gershenson, Kunal Rai, Russell R. Broaddus, P. Andrew Futreal
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-7 (2018)
Adult-type granulosa cell tumors of the ovary (aGCTs) are rare and recurrence is difficult to treat. Here, the authors observe in aGCT a novel recurrent somatic truncating mutation of KMT2D, more frequent in recurrent aGCT, and also non-genetic loss
Externí odkaz:
https://doaj.org/article/aaaf9455dfe54c3aac5bc54116b1802b
Autor:
Allison M. Burton-Chase, Wendy M. Parker, Kirsten M. Donato, Shannon McCormick, Ellen R. Gritz, Christopher I. Amos, Karen H. Lu, Patrick M. Lynch, Miguel A. Rodriguez-Bigas, Y. Nancy You, Susan K. Peterson
Publikováno v:
Journal of Patient-Reported Outcomes, Vol 2, Iss 1, Pp 1-6 (2018)
Abstract Purpose To compare health-related quality of life (HRQoL) in colorectal cancer (CRC) survivors with sporadic CRC to those with hereditary cancer, specifically Lynch syndrome (LS). Methods Participants completed a mailed self-administered que
Externí odkaz:
https://doaj.org/article/2e8823538f324238a462bf3b7cfa4129