Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Karen Gottwald"'
Autor:
Hendrik Hessefort, Elisabeth Rozanski, Carlo Unverzagt, Sascha Weidler, Karen Gottwald, Lukas Perkams, Tanja Kirsch, Simone Seeleithner, Markus Hessefort, Klaus Ole Bundgaard, Angelina Gross, David Rau, Christopher Günther Franz Graf
Publikováno v:
Angewandte Chemie (International ed. in English). 60(49)
Recombinant human erythropoietin (EPO) is the main therapeutic glycoprotein for the treatment of anemia in cancer and kidney patients. The in-vivo activity of EPO is carbohydrate-dependent with the number of sialic acid residues regulating its circul
Autor:
Carlo Unverzagt, Irene Boos, Karen Gottwald, Marina Schmälzlein, Claudia Pöhner, Sebastian Siebenhaar, Stefan Rose-John, Andrea Tröster, Carolin Lechner, Phanindra Velisetty, Andreas Reif, Volker Schubert
Publikováno v:
Angewandte Chemie (International ed. in English). 53(45)
Human interleukin 6 (IL-6) is a potent cytokine with immunomodulatory properties. As the influence of N-glycosylation on the in vivo activities of IL-6 could not be elucidated so far, a semisynthesis of homogeneous glycoforms of IL-6 was established