Výsledky vyhledávání - "Karen Gheesling Mullis"

A Phase 1/2 Dose-Escalation and Dose-Expansion Study of the Safety and Efficacy of Anti-CD7 Allogeneic CAR-T Cells (WU-CART-007) in Patients with Relapsed or Refractory T-Cell Acute Lymphoblastic Leukemia (T-ALL)/ Lymphoblastic Lymphoma (LBL)

Autor: Ayman Kabakibi, Matthew L. Cooper, Tom Leedom, Armin Ghobadi, Ibrahim Aldoss, Alexander S. Hamil, Deepa Bhojwani, Jan K Davidson-Moncada, Eileen McNulty, Frederick L. Locke, Preeta Dasgupta, Karen Gheesling Mullis, Ryan J. Mattison, Kenneth M Chrobak, Shannon L. Maude, John F. DiPersio

Publikováno v: Blood. 138:4829-4829

Background T-ALL/LBL represent a class of devastating hematologic cancers with high rates of relapse and mortality in both children and adults. Despite intensive multi-agent chemotherapy regimens, fewer than 50% of adults and 85% of children with T-A

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::21114a2df6a0ac4b4aea29a05e65f94c
https://doi.org/10.1182/blood-2021-146841

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Sequence Analysis of theCandida albicans ADE2 Gene and Physical Separation of the Two Functionally Distinct Domains of the Phosphoribosylaminoimidazole Carboxylase

Autor: Jon J. Schmuke, Stanton B. Dotson, Sheri L. Bonar, Karen Gheesling Mullis, V. Jo Davisson

Publikováno v: Yeast. 13:769-776

An ADE2 genomic clone from the pathogenic fungus, Candida albicans, was isolated by complementation of an Escherichia coli purK mutant and the gene was analysed by DNA sequencing. A 1707 bp open reading frame was identified encoding a polypeptide of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::1f189af5fce390833c58e2b29c58fd46
https://doi.org/10.1002/(sici)1097-0061(19970630)13:8<769::aid-yea133>3.0.co

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The synthesis of substrates and two assays for the detection of N-acetylglucosamine-1-phosphodiester α-N-acetylglucosaminidase (uncovering enzyme)

Autor: Karen Gheesling Mullis, Catherine M. Ketcham

Publikováno v: Analytical Biochemistry. 205:200-207

A method for the synthesis and purification of large quantities of four radiolabeled substrates for quantitation of uncovering enzyme is described. Four substrates, [3H]GlcNAc-alpha-P-Man alpha Me, [3H]GlcNAc-alpha-P-uteroferrin, [3H]GlcNAc alpha-P-M

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25f6ba37056421a7818fbc6015e87b18
https://doi.org/10.1016/0003-2697(92)90424-6

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Relative accessibility of N-acetylglucosamine in trimers of the adenovirus types 2 and 5 fiber proteins

Autor: Richard B. Marchase, Gerald W. Hart, Robert S. Haltiwanger, Jeffrey A. Engler, Karen Gheesling Mullis

Publikováno v: Journal of Virology. 64:5317-5323

Fiber is an adenovirus capsid protein responsible for virus attachment to the cell surface and contains O-linked N-acetylglucosamine (GlcNAc). Results of both amino acid analysis and Dionex chromatography indicated that 3 to 4 and 1.7 to 2.5 mol of G

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ea73dc22f27db84dd99dbf0f6df26dd
https://doi.org/10.1128/jvi.64.11.5317-5323.1990

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