Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Karen Geoffroy"'
Autor:
Karen Geoffroy, Bruna Araripe Saraiva, Melissa Viens, Delphine Béland, Marie-Claude Bourgeois-Daigneault
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-14 (2023)
Abstract Proteasome dependency is a feature of many cancers that can be targeted by proteasome inhibitors. For some cancer types, notably breast cancer and triple-negative breast cancer (TNBC), high mRNA expression of a modified form of the proteasom
Externí odkaz:
https://doaj.org/article/2b77bca2eb564e7e9fb4db961860dee6
Autor:
Karen Geoffroy, Patrick Laplante, Sylvie Clairefond, Feryel Azzi, Dominique Trudel, Jean-Baptiste Lattouf, John Stagg, Fred Saad, Anne-Marie Mes-Masson, Marie-Claude Bourgeois-Daigneault, Jean-François Cailhier
Publikováno v:
Cancers, Vol 14, Iss 11, p 2790 (2022)
Milk fat globule-epidermal growth factor-8 (MFG-E8) is a glycoprotein secreted by different cell types, including apoptotic cells and activated macrophages. MFG-E8 is highly expressed in a variety of cancers and is classically associated with tumor g
Externí odkaz:
https://doaj.org/article/ba5e56fdcfc34145ad808e9f927c502f
Autor:
Benoit Brilland, Patrick Laplante, Pamela Thebault, Karen Geoffroy, Marie-Joëlle Brissette, Mathieu Latour, Michaël Chassé, Shijie Qi, Marie-Josée Hébert, Héloïse Cardinal, Jean-François Cailhier
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 8, p 4094 (2022)
Transplant vasculopathy is characterized by endothelial apoptosis, which modulates the local microenvironment. Milk fat globule epidermal growth factor 8 (MFG-E8), which is released by apoptotic endothelial cells, limits tissue damage and inflammatio
Externí odkaz:
https://doaj.org/article/a0ee01e5591340dea9d5761dab471880
Autor:
Claire Franczak, Andréa Witz, Karen Geoffroy, Jessica Demange, Marie Rouyer, Marie Husson, Vincent Massard, Céline Gavoille, Aurélien Lambert, Pauline Gilson, Nicolas Gambier, Julien Scala-Bertola, Jean-Louis Merlin, Alexandre Harlé
Publikováno v:
PLoS ONE, Vol 15, Iss 1, p e0227294 (2020)
BACKGROUND:Cell-free DNA detection is becoming a surrogate assay for tumor genotyping. Biological fluids often content a very low amount of cell-free tumor DNA and assays able to detect very low allele frequency mutant with a few quantities of DNA ar
Externí odkaz:
https://doaj.org/article/2d2a0901bd524592b14f78b4b389cbf9
Autor:
Victor Mullins-Dansereau, Grégory Petrazzo, Karen Geoffroy, Delphine Béland, Marie-Claude Bourgeois-Daigneault
Publikováno v:
OncoImmunology, Vol 8, Iss 11 (2019)
Oncolytic viruses (OVs) are a novel class of cancer biotherapeutics with the ability to kill cancers and trigger anti-tumor immunity. Using murine models of cancer in pre-clinical proof-of-concept studies, we found that neoadjuvant OV administration
Externí odkaz:
https://doaj.org/article/905b9199b4cb44f3aafc5b1404ab79e3
Publikováno v:
Cytokine & Growth Factor Reviews. 56:49-58
Interferons (IFN) are potent immune stimulators that play key roles in both innate and adaptive immune responses. They are considered the first line of defense against viral pathogens and can even be used as treatments to boost the immune system. Whi
Autor:
Marie-Claude Bourgeois-Daigneault, Grégory Petrazzo, Delphine Béland, Karen Geoffroy, Victor Mullins-Dansereau
Publikováno v:
OncoImmunology
OncoImmunology, Taylor & Francis, 2019, 8 (11), pp.e1655363. ⟨10.1080/2162402X.2019.1655363⟩
Oncoimmunology
OncoImmunology, Vol 8, Iss 11 (2019)
OncoImmunology, Taylor & Francis, 2019, 8 (11), pp.e1655363. ⟨10.1080/2162402X.2019.1655363⟩
Oncoimmunology
OncoImmunology, Vol 8, Iss 11 (2019)
Oncolytic viruses (OVs) are a novel class of cancer biotherapeutics with the ability to kill cancers and trigger anti-tumor immunity. Using murine models of cancer in pre-clinical proof-of-concept studies, we found that neoadjuvant OV administration
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4ef168e4287fbde01f7961b6c140a14
https://hal.archives-ouvertes.fr/hal-02628351
https://hal.archives-ouvertes.fr/hal-02628351
Autor:
Julien Scala-Bertola, Pauline Gilson, Marie Husson, Alexandre Harlé, Vincent Massard, Céline Gavoille, Jessica Demange, Andréa Witz, Aurélien Lambert, Jean-Louis Merlin, Nicolas Gambier, Marie Rouyer, Claire Franczak, Karen Geoffroy
Publikováno v:
PLoS ONE
PLoS ONE, Public Library of Science, 2020, 15 (1), pp.e0227294. ⟨10.1371/journal.pone.0227294⟩
PLoS ONE, Vol 15, Iss 1, p e0227294 (2020)
PLoS ONE, Public Library of Science, 2020, 15 (1), pp.e0227294. ⟨10.1371/journal.pone.0227294⟩
PLoS ONE, Vol 15, Iss 1, p e0227294 (2020)
International audience; Background: Cell-free DNA detection is becoming a surrogate assay for tumor genotyping. Biological fluids often content a very low amount of cell-free tumor DNA and assays able to detect very low allele frequency mutant with a
Publikováno v:
FEBS Letters. 579:1249-1254
In this study, the effects of short-term diabetes (4 days) on rat renal glomerular cells proliferation and the potential involvement of sphingolipids in this process were investigated. Immunohistochemical analysis showed that streptozotocin (STZ)-ind
Publikováno v:
Journal of Biological Chemistry. 279:34343-34352
Advanced glycation end-products (AGE) are generated by chronic hyperglycaemia and may cause diabetic microvascular complications such as diabetic nephropathy. Many factors influence the development of diabetic nephropathy; however, dysregulation of m