Výsledky vyhledávání - "Karen Flatten"

Data from Drug Efflux by Breast Cancer Resistance Protein Is a Mechanism of Resistance to the Benzimidazole Insulin-Like Growth Factor Receptor/Insulin Receptor Inhibitor, BMS-536924

Autor: Paul Haluska, Scott H. Kaufmann, Charles Erlichman, Marco M. Gottardis, Douglas D. Ross, Jennifer D. Tibodeau, Takeo Nakanishi, Cynthia Ten Eyck, Yan W. Asmann, Karen Flatten, Joan M. Carboni, Fei Huang, Xiaonan Hou

Preclinical investigations have identified insulin-like growth factor (IGF) signaling as a key mechanism for cancer growth and resistance to clinically useful therapies in multiple tumor types including breast cancer. Thus, agents targeting and block

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0fbd5465fc9b4aaf920a287c41441376
https://doi.org/10.1158/1535-7163.c.6531158.v1

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Supplementary Figure 1 from Drug Efflux by Breast Cancer Resistance Protein Is a Mechanism of Resistance to the Benzimidazole Insulin-Like Growth Factor Receptor/Insulin Receptor Inhibitor, BMS-536924

Supplementary Figure 1 from Drug Efflux by Breast Cancer Resistance Protein Is a Mechanism of Resistance to the Benzimidazole Insulin-Like Growth Factor Receptor/Insulin Receptor Inhibitor, BMS-536924

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b4d25a4bed8d23420c5d7d440792c19f
https://doi.org/10.1158/1535-7163.22483487.v1

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Supplementary Figure 2B from Drug Efflux by Breast Cancer Resistance Protein Is a Mechanism of Resistance to the Benzimidazole Insulin-Like Growth Factor Receptor/Insulin Receptor Inhibitor, BMS-536924

Supplementary Figure 2A from Drug Efflux by Breast Cancer Resistance Protein Is a Mechanism of Resistance to the Benzimidazole Insulin-Like Growth Factor Receptor/Insulin Receptor Inhibitor, BMS-536924

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10da2daab2cc7cd9211b62fde0a4a109
https://doi.org/10.1158/1535-7163.22483478

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Supplementary Figure 3 from Drug Efflux by Breast Cancer Resistance Protein Is a Mechanism of Resistance to the Benzimidazole Insulin-Like Growth Factor Receptor/Insulin Receptor Inhibitor, BMS-536924

Supplementary Figure 3 from Drug Efflux by Breast Cancer Resistance Protein Is a Mechanism of Resistance to the Benzimidazole Insulin-Like Growth Factor Receptor/Insulin Receptor Inhibitor, BMS-536924

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f33a97bc95be6f189ea95696ab2ac63
https://doi.org/10.1158/1535-7163.22483475

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Supplementary Figure Legends from Drug Efflux by Breast Cancer Resistance Protein Is a Mechanism of Resistance to the Benzimidazole Insulin-Like Growth Factor Receptor/Insulin Receptor Inhibitor, BMS-536924

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c7d885e6742f7557bdf314277b02c6c
https://doi.org/10.1158/1535-7163.22483472.v1

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Mcl-1 as a buffer for proapoptotic Bcl-2 family members during TRAIL-induced apoptosis: a mechanistic basis for sorafenib (Bay 43-9006)-induced TRAIL sensitization

Autor: Xue Wei, Meng, Sun-Hee, Lee, Haiming, Dai, David, Loegering, Chunrong, Yu, Karen, Flatten, Paula, Schneider, Nga T, Dai, Shaji K, Kumar, B Douglas, Smith, Judith E, Karp, Alex A, Adjei, Scott H, Kaufmann

Publikováno v: The Journal of biological chemistry. 282(41)

Previous studies have suggested that Mcl-1, an antiapoptotic Bcl-2 homolog that does not exhibit appreciable affinity for the caspase 8-generated C-terminal Bid fragment (tBid), diminishes sensitivity to tumor necrosis factor-alpha-related apoptosis-

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::8bea174f1ac255abe1d6f236cce974e7
https://pubmed.ncbi.nlm.nih.gov/17698840

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