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pro vyhledávání: '"Karen Ferrante"'
Autor:
Karen Ferrante, W. David Lewis, Roger L. Jenkins, Keith E. Stuart, Mark S. Huberman, Pedro M. Sanz-Altamira
Publikováno v:
Cancer. 82:2321-2325
BACKGROUND Unresectable adenocarcinoma of the biliary tree are associated with a very poor prognosis. 5-fluorouracil (5-FU) combination regimens have produced objective response rates in approximately 10-20% of patients. Leucovorin increases the sele
Publikováno v:
Cancer chemotherapy and pharmacology.
The positive impact on survival of traditional chemotherapeutic agents has renewed interest in developing newer cytotoxic agents and orally active compounds with improved therapeutic indices. In addition, new insights into the pathways of human tumor