Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Karen Fernie"'
Autor:
Ben C. Maddison, Karen Fernie, Nora Hunter, Allister Smith, Robert A. Somerville, Keith Bishop, Kevin C. Gough
Publikováno v:
Archives of Virology
Somerville, R A, Fernie, K, Smith, A, Bishop, K, Maddison, B C, Gough, K C & Hunter, N 2019, ' BSE infectivity survives burial for five years with only limited spread ', Archives of Virology . https://doi.org/10.1007/s00705-019-04154-8
Somerville, R A, Fernie, K, Smith, A, Bishop, K, Maddison, B C, Gough, K C & Hunter, N 2019, ' BSE infectivity survives burial for five years with only limited spread ', Archives of Virology . https://doi.org/10.1007/s00705-019-04154-8
The carcasses of animals infected with bovine spongiform encephalopathy (BSE), scrapie or chronic wasting disease (CWD) that remain in the environment (exposed or buried) may continue to act as reservoirs of infectivity. We conducted two experiments
Publikováno v:
Journal of Hospital Infection. 80:46-51
Summary Background The transmission of bovine spongiform encephalopathy (BSE) to humans as variant Creutzfeldt–Jakob Disease (vCJD) raised concerns about potential secondary transmissions due to the resistance of the agents causing transmissible sp
Publikováno v:
Journal of Hospital Infection. 66:52-58
Summary Iatrogenic transmission of transmissible spongiform encephalopathies (TSEs) has been demonstrated via surgical instruments and there is concern over the efficacy of conventional decontamination techniques used to reprocess reusable instrument
Autor:
Cindy M. Cooke, Robert A Somerville, Karen Fernie, Joanne Rodger, George Shaw, Allister Smith
Publikováno v:
Environmental Science & Technology. 41:811-817
The transmissible spongiform encephalopathies (TSEs) are caused by infectious agents whose structures have not been fully characterized but include abnormal forms of the host protein PrP, designated PrP(Sc), which are deposited in infected tissues. T
Publikováno v:
Journal of General Virology. 86:241-246
Transmissible spongiform encephalopathies (TSEs), sometimes known as prion diseases, are caused by an infectious agent whose molecular properties have not been determined. Traditionally, different strains of TSE diseases are characterized by a series
Publikováno v:
Journal of General Virology. 83:3199-3204
Five experimentally maintained strains of scrapie and BSE agents have been passaged in two PrP genotypes of mice. Brain macerates were autoclaved at 126 °C and the levels of surviving infectivity were measured by titration. There was a large differe
Autor:
Erick Schmidt, Robert A. Somerville, D M Taylor, Allister Smith, Randall Andrews, Karen Fernie
Publikováno v:
Process Biochemistry. 44:1060-1062
The infectious agents causing transmissible spongiform encephalopathies (TSEs), sometimes called prions, are notoriously difficult to completely inactivate or destroy. Here we tested a thermal hydrolysis system which combines saturated steam heating
Publikováno v:
Veterinary Record. 143:6-9
The study was designed to determine the effect on bovine spongiform encephalopathy (BSE) and scrapie agents of the solvent extraction processes used in the past by British renderers. The raw material was mouse spleen infected with either the 22A stra
Publikováno v:
Veterinary Microbiology. 58:167-174
Brain-tissue infected with scrapie-like agents remains infectious after histological fixation, and represents a source of occupational exposure. Infectivity titres in formol or paraformaldehyde-lysine-periodate (PLP)-fixed mouse-brains infected with
Publikováno v:
Biotechnology and applied biochemistry. 47(Pt 4)
The causal infectious agents of TSEs (transmissible spongiform encephalopathies or prion diseases) are renowned for their resistance to complete inactivation. Survival of TSE infectivity after autoclaving potentially compromises many procedures where