Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Karen F. McGregor"'
Publikováno v:
PLoS Computational Biology, Vol 3, Iss 1, p e14 (2007)
Many microorganisms exhibit high levels of intragenic recombination following horizontal gene transfer events. Furthermore, many microbial genes are subject to strong diversifying selection as part of the pathogenic process. A multiple sequence align
Externí odkaz:
https://doaj.org/article/f705880e4a4d48629fdb067fd88fa9fe
Autor:
Bernard Beall, Alicia Bennett, Debra E. Bessen, Brian G. Spratt, Nicole Bilek, Awdhesh Kalia, Karen F. McGregor
Publikováno v:
Journal of Bacteriology. 186:4285-4294
A long-term goal is to characterize the full range of genetic diversity withinStreptococcus pyogenesas it exists in the world today. Since theemmlocus is subject to strong diversifying selection,emmtype was used as a guide for identifying a genetical
Autor:
Shiranee Sriskandan, Frances Davies, Brian G. Spratt, Karen F. McGregor, Claire E. Turner, Deborah L. W. Chong, Bruno Pichon, Leili Farzaneh, Mary Sommerlad, Matthew T. G. Holden, Androulla Efstratiou
Publikováno v:
PLoS ONE, Vol 7, Iss 10, p e46376 (2012)
PLoS ONE
PLoS ONE
Streptococcus pyogenes M/emm3 strains have been epidemiologically linked with enhanced infection severity and risk of streptococcal toxic shock syndrome (STSS), a syndrome triggered by superantigenic stimulation of T cells. Comparison of S. pyogenes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c10ce6ed24db2ecd0263a657c6a9ce0
Autor:
Jonathan R. Carapetis, Rebecca J. Towers, Steven Y. C. Tong, Bart J. Currie, Peter K. Fagan, Leisha J. Richardson, Flavia Huygens, Philip M. Giffard, Karen F. McGregor
Publikováno v:
Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases. 17(9)
The major limitation of current typing methods for Streptococcus pyogenes , such as emm sequence typing and T typing, is that these are based on regions subject to considerable selective pressure. Multilocus sequence typing (MLST) is a better indicat
Publikováno v:
BMC Microbiology, Vol 8, Iss 1, p 59 (2008)
BMC Microbiology
BMC Microbiology
Background The M type-specific surface protein antigens encoded by the 5' end of emm genes are targets of protective host immunity and attractive vaccine candidates against infection by Streptococcus pyogenes, a global human pathogen. A history of ge
Publikováno v:
PLoS Computational Biology
PLoS Computational Biology, Vol 3, Iss 1, p e14 (2007)
PLoS Computational Biology, Vol 3, Iss 1, p e14 (2007)
Many microorganisms exhibit high levels of intragenic recombination following horizontal gene transfer events. Furthermore, many microbial genes are subject to strong diversifying selection as part of the pathogenic process. A multiple sequence align
Autor:
Karen F. McGregor, Brian G. Spratt
Publikováno v:
Journal of clinical microbiology. 43(4)
Between July and October 2003, 121 clinical isolates of group A streptococci (GAS) were collected from a London hospital and characterized by multilocus sequence typing (MLST) to determine the identity and prevalence of clones circulating within this
Autor:
Nicole Bilek, Brian G. Spratt, Alicia Bennett, Jonathan R. Carapetis, Debra E. Bessen, Bart J. Currie, Awdhesh Kalia, Karen F. McGregor, Kadaba S. Sriprakash, Bernard Beall
Publikováno v:
The Journal of infectious diseases. 189(4)
Group A streptococci (GAS) cause several human diseases that differentially affect distinct host populations. Genotypes were defined by multilocus sequence typing and emm typing for 137 organisms collected from individuals in a remote aboriginal isla
Publikováno v:
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America. 37(9)
Surveillance of group A streptococcus (GAS) infections in Sweden during 1996-1997 indicated that T28 isolates were dominant, whereas T1M1 infections were uncommon. Circulating T28 isolates were nearly all emm28, MLST52, and these clones had also been
Autor:
Luke Tysall, Neil Woodford, Marie-France I. Palepou, Hilary-Kay Young, Carla Nolan, Karen F. McGregor
A total of 204 vanB enterococcal isolates, isolated between 1989 and 1999 from patients in 59 different hospitals in England, Wales, and Scotland and from a single hospital in the Republic of Ireland, were examined. Nucleotide sequencing and HhaI dig
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aad76ac42f01e73193424942c6b0c785
https://repository.uwl.ac.uk/id/eprint/94/1/Antimicrob-Agents-Chemother-2001-McGregor.pdf
https://repository.uwl.ac.uk/id/eprint/94/1/Antimicrob-Agents-Chemother-2001-McGregor.pdf